Prof. Assaf Friedler

Prof. Assaf Friedler

Hebrew University of Jerusalem

H-index: 43

Asia-Israel

About Prof. Assaf Friedler

Prof. Assaf Friedler, With an exceptional h-index of 43 and a recent h-index of 19 (since 2020), a distinguished researcher at Hebrew University of Jerusalem, specializes in the field of peptides, protein interactions, medicinal chemistry, biophysical chemistry, intrinsically disordered proteins.

His recent articles reflect a diverse array of research interests and contributions to the field:

Molecular Mechanism of STIL Coiled-Coil Domain Oligomerization

A combination of a cell penetrating peptide and a protein translation inhibitor kills metastatic breast cancer cells

Visualization of Molecular Permeation into a Multi-compartment Phospholipid Vesicle

Amyloid Aggregation Is Potently Slowed Down by Osmolytes Due to Compaction of Partially Folded State

The oligomerization domains of the APC protein mediate liquid-liquid phase separation that is phosphorylation controlled

Fibril Paint to detect Amyloids and determine Fibril Length

Peptide permeation across a phosphocholine membrane: An atomically detailed mechanism determined through simulations and supported by experimentation

Using a Single Peptide to Electrochemically Sense Multiple Kinases

Prof. Assaf Friedler Information

University

Position

Institute of Chemistry The

Citations(all)

6011

Citations(since 2020)

1597

Cited By

5048

hIndex(all)

43

hIndex(since 2020)

19

i10Index(all)

108

i10Index(since 2020)

53

Email

University Profile Page

Hebrew University of Jerusalem

Google Scholar

View Google Scholar Profile

Prof. Assaf Friedler Skills & Research Interests

peptides

protein interactions

medicinal chemistry

biophysical chemistry

intrinsically disordered proteins

Top articles of Prof. Assaf Friedler

Title

Journal

Author(s)

Publication Date

Molecular Mechanism of STIL Coiled-Coil Domain Oligomerization

International Journal of Molecular Sciences

Mai Shamir

Freddie JO Martin

Derek N Woolfson

Assaf Friedler

2023/9/27

A combination of a cell penetrating peptide and a protein translation inhibitor kills metastatic breast cancer cells

Cell Death Discovery

Linda Rowland

Henri-Baptiste Marjault

Ola Karmi

DeAna Grant

Lauren J Webb

...

2023/8/31

Visualization of Molecular Permeation into a Multi-compartment Phospholipid Vesicle

The Journal of Physical Chemistry Letters

Ehud Neumann

Yang Sung Sohn

Sydney C Povilaitis

Alfredo E Cardenas

Ron Mittler

...

2023/7/7

Amyloid Aggregation Is Potently Slowed Down by Osmolytes Due to Compaction of Partially Folded State

Journal of Molecular Biology

Tommaso Garfagnini

Francesco Bemporad

Daniel Harries

Fabrizio Chiti

Assaf Friedler

2023/11/15

The oligomerization domains of the APC protein mediate liquid-liquid phase separation that is phosphorylation controlled

International Journal of Molecular Sciences

Shachar G Bressler

Amit Mitrany

Alon Wenger

Inke Näthke

Assaf Friedler

2023/3/30

Fibril Paint to detect Amyloids and determine Fibril Length

FA Dekker

T Garfagnini

G Mayer

MB Koopman

M Bergmeijer

...

2023/10/13

Peptide permeation across a phosphocholine membrane: An atomically detailed mechanism determined through simulations and supported by experimentation

The Journal of Physical Chemistry B

Alfredo E Cardenas

Chad I Drexler

Rachel Nechushtai

Ron Mittler

Assaf Friedler

...

2022/4/7

Using a Single Peptide to Electrochemically Sense Multiple Kinases

Biochemistry

Ohad Solomon

Israel Alshanski

Ariel Shitrit

Yu-Ju Chen

Assaf Friedler

...

2022/10/14

Front Cover: Kinase Sensing Based on Protein Interactions at the Catalytic Site (Chem. Eur. J. 17/2022)

Chemistry–A European Journal

Ohad Solomon

Hannah Sapir

Evgeniy Mervinetsky

Yu‐Ju Chen

Assaf Friedler

...

2022/3/22

Peptide‐Based Inhibitors that Target the Docking Site of ERK2

Israel Journal of Chemistry

Ohad Solomon

Zohar Shpilt

Hannah Sapir

Shir Marom

Shai Bibas

...

2022/10

Kinase Sensing Based on Protein Interactions at the Catalytic Site

Chemistry–A European Journal

Ohad Solomon

Hannah Sapir

Evgeniy Mervinetsky

Yu‐Ju Chen

Assaf Friedler

...

2022/3/22

Accelerated Multiphosphorylated Peptide Synthesis

Dana Grunhaus

Estefanía Rossich Molina

Roni Cohen

Tamar Stein

Assaf Friedler

...

2022/7/12

A peptide-derived strategy for specifically targeting the mitochondria and ER of cancer cells: a new approach in fighting cancer

Chemical Science

Yang Sung Sohn

Alfredo E Cardenas

Ola Karmi

Merav Darash Yahana

Tal Gruman

...

2022

Electrochemical biosensors based on peptide-kinase interactions at the kinase docking site

Biosensors and Bioelectronics

Pralhad Namdev Joshi

Evgeniy Mervinetsky

Ohad Solomon

Yu-Ju Chen

Shlomo Yitzchaik

...

2022/7/1

Targeting Protein Interaction Hotspots Using Structured and Disordered Chimeric Peptide Inhibitors

ACS Chemical Biology

Guy Mayer

Zohar Shpilt

Hadar Kowalski

Edit Y Tshuva

Assaf Friedler

2022/6/27

A peptide strategy for inhibiting different protein aggregation pathways in disease

bioRxiv

Tommaso Garfagnini

Luca Ferrari

Margreet B Koopman

Sem Halters

Eline Van Kappel

...

2022/10/22

Towards molecular understanding of the pH dependence characterizing NhaA of which structural fold is shared by other transporters

Journal of Molecular Biology

R Mondal

A Rimon

G Masrati

N Ben-Tal

A Friedler

...

2021/9/17

Osmolytes and crowders regulate aggregation of the cancer-related L106R mutant of the Axin protein

Biophysical Journal

Tommaso Garfagnini

Yael Levi-Kalisman

Daniel Harries

Assaf Friedler

2021/8/17

Automated synthesis of heavily phosphorylated peptides

European Journal of Organic Chemistry

Dana Grunhaus

Assaf Friedler

Mattan Hurevich

2021/7/15

Integrating site-specific peptide reporters and targeted mass spectrometry enables rapid substrate-specific kinase assay at the nanogram cell level

Analytica Chimica Acta

Aaron James F Reyes

Reta Birhanu Kitata

Mira Anne C dela Rosa

Yi-Ting Wang

Pei-Yi Lin

...

2021/4/22

See List of Professors in Prof. Assaf Friedler University(Hebrew University of Jerusalem)

Co-Authors

H-index: 160
Alan Fersht

Alan Fersht

University of Cambridge

H-index: 97
Hermona Soreq

Hermona Soreq

Hebrew University of Jerusalem

H-index: 57
Patricia A. Jennings

Patricia A. Jennings

University of California, San Diego

H-index: 54
Rachel Nechushtai

Rachel Nechushtai

Hebrew University of Jerusalem

H-index: 50
Eric J Sundberg

Eric J Sundberg

Emory & Henry College

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