Philippe Froguel

Philippe Froguel

Imperial College London

H-index: 186

Europe-United Kingdom

About Philippe Froguel

Philippe Froguel, With an exceptional h-index of 186 and a recent h-index of 103 (since 2020), a distinguished researcher at Imperial College London, specializes in the field of Diabetes, Obesity, Genetics, Genomics, Precision Medicine.

His recent articles reflect a diverse array of research interests and contributions to the field:

Role of the Unfolded Protein Response in Cell Compensation and Failure during Diabetes

Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics

Dominant PDX1 deficiency causes highly penetrant diabetes at different ages, associated with obesity and exocrine pancreatic deficiency: Lessons for precision medicine

Pathogenic, Total Loss-of-Function DYRK1B Variants Cause Monogenic Obesity Associated With Type 2 Diabetes

Pathogenic monoallelic variants in GLIS3 increase type 2 diabetes risk and identify a subgroup of patients sensitive to sulfonylureas

Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD

The Gut Microbiome Strongly Mediates the impact of Lifestyle combined variables on Cardiometabolic Phenotypes

A framework for conducting time-varying genome-wide association studies: An application to body mass index across childhood in six multiethnic cohorts

Philippe Froguel Information

University

Position

and CNRS-Lille univ

Citations(all)

161383

Citations(since 2020)

45857

Cited By

136178

hIndex(all)

186

hIndex(since 2020)

103

i10Index(all)

671

i10Index(since 2020)

455

Email

University Profile Page

Imperial College London

Google Scholar

View Google Scholar Profile

Philippe Froguel Skills & Research Interests

Diabetes

Obesity

Genetics

Genomics

Precision Medicine

Top articles of Philippe Froguel

Title

Journal

Author(s)

Publication Date

Role of the Unfolded Protein Response in Cell Compensation and Failure during Diabetes

Nabil Rabhi

Elisabet Salas

Philippe Froguel

Jean-Sébastien Annicotte

2030

Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics

Molecular metabolism

Arnaud Dance

Justine Fernandes

Bénédicte Toussaint

Emmanuel Vaillant

Raphaël Boutry

...

2024/1/1

Dominant PDX1 deficiency causes highly penetrant diabetes at different ages, associated with obesity and exocrine pancreatic deficiency: Lessons for precision medicine

Diabetes & Metabolism

Youssef Kouidrat

Lauriane Le Collen

Martine Vaxillaire

Aurélie Dechaume

Bénédicte Toussaint

...

2024/1/1

Pathogenic, Total Loss-of-Function DYRK1B Variants Cause Monogenic Obesity Associated With Type 2 Diabetes

Diabetes Care

Lise Folon

Morgane Baron

Victoria Scherrer

Bénédicte Toussaint

Emmanuel Vaillant

...

2024/3/1

Pathogenic monoallelic variants in GLIS3 increase type 2 diabetes risk and identify a subgroup of patients sensitive to sulfonylureas

Diabetologia

Sarah Meulebrouck

Victoria Scherrer

Raphaël Boutry

Bénédicte Toussaint

Emmanuel Vaillant

...

2024/2

Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD

JHEP Reports

Manuel Johanns

Joel T Haas

Violetta Raverdy

Jimmy Vandel

Julie Chevalier-Dubois

...

2024/1/1

The Gut Microbiome Strongly Mediates the impact of Lifestyle combined variables on Cardiometabolic Phenotypes

medRxiv

Solia Adriouch

Eugeni Belda

Timothy D Swartz

Sofia Forslund

Tiphaine Le Roy

...

2024/1/13

A framework for conducting time-varying genome-wide association studies: An application to body mass index across childhood in six multiethnic cohorts

medRxiv

Kimberley Burrows

Anni Heiskala

Jonathan P Bradfield

Zhanna Balkhiyarova

Lijiao Ning

...

2024

High morbidity and mortality in children with untreated congenital deficiency of leptin or its receptor

Cell Reports Medicine

Sadia Saeed

Roohia Khanam

Qasim M Janjua

Jaida Manzoor

Lijiao Ning

...

2023/9/19

Et si l’espace de soins devenait un espace de réconciliation pour le patient? Une étude de patients en situation de vulnérabilité

Lynn Abou Jaoudé

Hélène Gorge

Coralie Berthier

Antonia Gasch-Illescas

Matthias Vandesquille

...

2023/11/16

Identification of biomarkers for glycaemic deterioration in type 2 diabetes

Nature communications

Roderick C Slieker

Louise A Donnelly

Elina Akalestou

Livia Lopez-Noriega

Rana Melhem

...

2023/5/3

Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming

Iscience

Frédérik Oger

Maeva Moreno

Mehdi Derhourhi

Bryan Thiroux

Lionel Berberian

...

2023/7/21

Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials

The Lancet Diabetes & Endocrinology

Adem Y Dawed

Andrea Mari

Andrew Brown

Timothy J McDonald

Lin Li

...

2023/1/1

Genetic insights into resting heart rate and its role in cardiovascular disease

Nature communications

Yordi J van de Vegte

Ruben N Eppinga

M Yldau van der Ende

Yanick P Hagemeijer

Yuvaraj Mahendran

...

2023/8/2

High-throughput quantitative screening of glucose-stimulated insulin secretion and insulin content using automated MALDI-TOF mass spectrometry

Cells

Clément Philippe Delannoy

Egon Heuson

Adrien Herledan

Frederik Oger

Bryan Thiroux

...

2023/3/9

Identification of myokines susceptible to improve glucose homeostasis after bariatric surgery

European Journal of Endocrinology

Laura Orioli

Mickaël Canouil

Kiswendsida Sawadogo

Lijiao Ning

Louise Deldicque

...

2023/9

Time-of-day-dependent variation of the hepatic transcriptome and metabolome is disrupted in non-alcoholic fatty liver disease patients

bioRxiv

Manuel Johanns

Joel T Haas

Violetta Raverdy

Jimmy Vandel

Julie Chevalier-Dubois

...

2023/4/6

Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci

Molecular psychiatry

Lisa de Las Fuentes

Yun Ju Sung

Raymond Noordam

Thomas Winkler

Mary F Feitosa

...

2021/6

Heterozygous pathogenic variants in POMC are not responsible for monogenic obesity: Implication for MC4R agonist use

Genetics in Medicine

Lauriane Le Collen

Brigitte Delemer

Christine Poitou

Martine Vaxillaire

Bénédicte Toussaint

...

2023/7/1

β-Cell–Specific E2f1 Deficiency Impairs Glucose Homeostasis, β-Cell Identity, and Insulin Secretion

Diabetes

Frédérik Oger

Cyril Bourouh

Marika Elsa Friano

Emilie Courty

Laure Rolland

...

2023/8/1

See List of Professors in Philippe Froguel University(Imperial College London)