Philip C. Biggin
University of Oxford
H-index: 49
Europe-United Kingdom
Top articles of Philip C. Biggin
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Computational characterization of the binding of allosteric potentiators to the α4-α4 interface of the α4β2 LS nicotinic acetylcholine receptor | Biophysical Journal | Franco Viscarra Philip C Biggin Isabel Bermudez | 2024/2/8 |
Selective Potentiation of the (α4)3(β2)2 Nicotinic Acetylcholine Receptor Response by NS9283 Analogues | ACS Chemical Neuroscience | Rebecca Appiani Franco Viscarra Philip C Biggin Isabel Bermudez Alessandro Giraudo | 2024/3/21 |
Understanding transport processes with simulation | Biophysical Journal | Philip Biggin | 2024/2/8 |
Recovery from desensitization in GluA2 AMPA receptors is affected by a single mutation in the N-terminal domain interface | Journal of Biological Chemistry | Andreas Haahr Larsen Amanda M Perozzo Philip C Biggin Derek Bowie Jette Sandholm Kastrup | 2024/3/1 |
Cryo-EM structures of nanodisc reconstituted ligand-gated ion channel GLIC in various conformations reveal state-dependent protein-lipid interactions and gating mechanism | Biophysical Journal | Nikhil Bharambe Zhuowen Li David Seiferth Asha Manikkoth Balakrishna Philip C Biggin | 2024/2/8 |
Efficient large-scale exploration of fragment hit progression by exploiting binding-site purification of actives (B-SPA) through combining multi-step array synthesis and HT … | Harold Grosjean Anthony Aimon Storm Hassell-Hart Warren Thompson Lizbé Koekemoer | 2024/2/9 | |
The mechanism of mammalian proton-coupled peptide transporters | bioRxiv | Simon M Lichtinger Joanne L Parker Simon Newstead Philip Biggin | 2024 |
The mechanism of mammalian peptide transporters | Biophysical Journal | Simon M Lichtinger Simon Newstead Philip C Biggin | 2024/2/8 |
Exploring the Influence of Pore Shape on Conductance and Permeation | bioRxiv | David Seiferth Philip C Biggin | 2024 |
Physiological and pharmacological modulation of alpha3 glycine receptors | Biophysical Journal | Kayla J Kindig Eric Gibbs Seiferth David Philip C Biggin Sudha Chakrapani | 2024/2/8 |
Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment | Nature Communications | Nikhil Bharambe Zhuowen Li David Seiferth Asha Manikkoth Balakrishna Philip C Biggin | 2024/4/5 |
Conformational transitions and allosteric modulation in a heteromeric glycine receptor | Nature Communications | Eric Gibbs Emily Klemm David Seiferth Arvind Kumar Serban L Ilca | 2023/3/13 |
Small‐molecule positive allosteric modulation of homomeric kainate receptors GluK1‐3: development of screening assays and insight into GluK3 structure | The FEBS Journal | Yasmin Bay Raminta Venskutonytė Stine M Frantsen Thor S Thorsen Maria Musgaard | 2023/12/25 |
The role of loop dynamics in the prediction of ligand–protein binding enthalpy | Chemical Science | Süleyman Selim Çınaroğlu Philip C Biggin | 2023 |
Modelling solution structures of cyclic peptides-How good are we? | Biophysical Journal | Daniel Crusius Jason R Schnell Flaviu Cipcigan Philip C Biggin | 2023/2/10 |
Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs | Biophysical Journal | Arvind Kumar Kayla J Kindig Shanlin Rao Afroditi-Maria Zaki Sandip Basak | 2023/2/10 |
Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation | ACS Chemical Biology | Adam M Thomas Marta Serafini Emma K Grant Edward AJ Coombs Joseph P Bluck | 2023/10/24 |
Novel methods for the acceleration of protein simulation | Biophysical Journal | William Rochira Philip C Biggin | 2023/2/10 |
Exploring conformational transitions in membrane proteins with memento | Biophysical Journal | Simon Lichtinger Simon Newstead Philip C Biggin | 2023/2/10 |
Computed Protein–Protein Enthalpy Signatures as a Tool for Identifying Conformation Sampling Problems | Journal of Chemical Information and Modeling | Süleyman Selim Çınaroğlu Philip C Biggin | 2023/9/28 |
