Peter Stathopulos

Peter Stathopulos

Western University

H-index: 41

North America-Canada

About Peter Stathopulos

Peter Stathopulos, With an exceptional h-index of 41 and a recent h-index of 31 (since 2020), a distinguished researcher at Western University, specializes in the field of structural biology, calcium signaling, NMR spectroscopy, protein-protein interactions.

His recent articles reflect a diverse array of research interests and contributions to the field:

Human Cx50 Isoleucine177 prevents heterotypic docking and formation of functional gap junction channels with Cx43

Acetylenic tricyclic bis-(cyano enone) interacts with Cys 374 of actin, a residue necessary for stress fiber formation and cell migration

The MCU and MCUb amino-terminal domains tightly interact: mechanisms for low conductance assembly of the mitochondrial calcium uniporter complex.

An AI-informed NMR structure reveals a LETM1 F-EF-hand for two-way mitochondrial calcium regulation.

ERMA (TMEM94) is a P-type ATPase transporter for Mg2+ uptake in the endoplasmic reticulum

Cx31. 1 can selectively intermix with co-expressed connexins to facilitate its assembly into gap junctions

Human Cx50 isoleucine177 is critical for heterotypic docking and formation of functional gap junction channels with Cx43

Inherited disease-linked arginine76/75 mutants in Cx50 and Cx45 showed impaired homotypic and heterotypic gap junction function, but not Cx43

Peter Stathopulos Information

University

Position

Assistant Professor of Physiology and Pharmacology

Citations(all)

19202

Citations(since 2020)

8631

Cited By

12313

hIndex(all)

41

hIndex(since 2020)

31

i10Index(all)

65

i10Index(since 2020)

55

Email

University Profile Page

Western University

Google Scholar

View Google Scholar Profile

Peter Stathopulos Skills & Research Interests

structural biology

calcium signaling

NMR spectroscopy

protein-protein interactions

Top articles of Peter Stathopulos

Title

Journal

Author(s)

Publication Date

Human Cx50 Isoleucine177 prevents heterotypic docking and formation of functional gap junction channels with Cx43

American Journal of Physiology-Cell Physiology

Robert S Wong

Honghong Chen

Yi X Li

Jessica L Esseltine

Peter B Stathopulos

...

2024/2/1

Acetylenic tricyclic bis-(cyano enone) interacts with Cys 374 of actin, a residue necessary for stress fiber formation and cell migration

Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

Eddie Chan

Brennan S Dirk

Tadashi Honda

Peter B Stathopulos

Jimmy D Dikeakos

...

2024/2/1

The MCU and MCUb amino-terminal domains tightly interact: mechanisms for low conductance assembly of the mitochondrial calcium uniporter complex.

iScience

Megan Noble

Danielle M Colussi

Murray Junop

Peter B Stathopulos

2024/4/10

An AI-informed NMR structure reveals a LETM1 F-EF-hand for two-way mitochondrial calcium regulation.

bioRxiv

Qi Tong Lin

Danielle M Colussi

Taylor Lake

Peter Stathopulos

2024

ERMA (TMEM94) is a P-type ATPase transporter for Mg2+ uptake in the endoplasmic reticulum

Molecular Cell

Neelanjan Vishnu

Manigandan Venkatesan

Travis R Madaris

Mridula K Venkateswaran

Kristen Stanley

...

2024/4/4

Cx31. 1 can selectively intermix with co-expressed connexins to facilitate its assembly into gap junctions

Journal of Cell Science

Stephanie E Leighton

Robert S Wong

Sergiu A Lucaciu

Alexandra Hauser

Danielle Johnston

...

2024/4/1

Human Cx50 isoleucine177 is critical for heterotypic docking and formation of functional gap junction channels with Cx43

Biophysical Journal

Robert S Wong

Honghong Chen

Yi X Li

Jessica L Esseltine

Peter B Stathopulos

...

2024/2/8

Inherited disease-linked arginine76/75 mutants in Cx50 and Cx45 showed impaired homotypic and heterotypic gap junction function, but not Cx43

Biochemical Journal

Tianhe Li

Honghong Chen

Xiaole Li

Peter B Stathopulos

Donglin Bai

2023/7/17

From passage to inhibition: Uncovering the structural and physiological inhibitory mechanisms of MCUb in mitochondrial calcium regulation

Danielle M Colussi

Peter B Stathopulos

2023/1

The human MRS2 magnesium-binding domain is a regulatory feedback switch for channel activity

Life Science Alliance

Sukanthathulse Uthayabalan

Neelanjan Vishnu

Muniswamy Madesh

Peter B Stathopulos

2023/4/1

Limiting Mrs2-dependent mitochondrial Mg2+ uptake induces metabolic programming in prolonged dietary stress

Cell reports

Travis R Madaris

Manigandan Venkatesan

Soumya Maity

Miriam C Stein

Neelanjan Vishnu

...

2023/3/28

Inherited disease-linked arginine76 or equivalent residue mutants in Cx50 and Cx45 showed impaired homotypic and heterotypic gap junction function, but not Cx43

Biophysical Journal

Tianhe Li

Honghong Chen

Xiaole Li

Peter B Stathopulos

Donglin Bai

2023/2/10

Aromatically stacking the odds in favour of increased ORAI1 activation.

Cell Calcium

Peter B Stathopulos

Mitsuhiko Ikura

2023/12/21

The leucine zipper EF-hand containing transmembrane protein-1 EF-hand is an atypical tripartite calcium, temperature, and pH sensor

Biophysical Journal

QiTong Lin

Peter B Stathopulos

2023/2/10

Annexin a5 compositions and methods

2023/11/23

Defining the SPCA2C interactome identifies unique links to store-operated calcium entry

bioRxiv

Petra Samardzija

Melissa A Fenech

Ryann Lang

McKenzie C Carter

Stephanie Chen

...

2023

An S-glutathiomimetic provides structural insights into stromal interaction molecule-1 regulation

Journal of Molecular Biology

Christian Sirko

Matthew J Novello

Peter B Stathopulos

2022/12/30

The hydrophobic residues in amino terminal domains of Cx46 and Cx50 are important for their gap junction channel ion permeation and gating

International Journal of Molecular Sciences

Roa’a Jaradat

Xiaole Li

Honghong Chen

Peter B Stathopulos

Donglin Bai

2022/10/1

The leucine zipper EF‐hand containing transmembrane protein‐1 EF‐hand is a tripartite calcium, temperature, and pH sensor

Protein Science

Qi‐Tong Lin

Rachel Lee

Allen L Feng

Michael S Kim

Peter B Stathopulos

2021/4

Molecular nature and physiological role of the mitochondrial calcium uniporter channel

B Rita Alevriadou

Akshar Patel

Megan Noble

Sagnika Ghosh

Vishal M Gohil

...

2021/4/1

See List of Professors in Peter Stathopulos University(Western University)