Paul Dalby

Paul Dalby

University College London

H-index: 37

Europe-United Kingdom

About Paul Dalby

Paul Dalby, With an exceptional h-index of 37 and a recent h-index of 22 (since 2020), a distinguished researcher at University College London, specializes in the field of Therapeutic protein engineering, ability and formulation. Enzyme engineering..

His recent articles reflect a diverse array of research interests and contributions to the field:

Two-substrate enzyme engineering using small libraries that combine the substrate preferences from two different variant lineages

Plasmin Cleavage of Beta-2-Glycoprotein I Alters its Structure and Ability to Bind to Pathogenic Antibodies

A transaminase-mediated aldol reaction and applications in cascades to styryl pyridines

Investigation of the Solid-State Interactions in Lyophilized Human G-CSF Using Hydrogen–Deuterium Exchange Mass Spectrometry

Machine learning integrating protein structure, sequence, and dynamics to predict the enzyme activity of bovine enterokinase variants

Time-resolved method of protein analysis

Enhancement of thermal stability of Bacillus subtilis 168 glycosyltransferase YjiC based on PoPMuSiC algorithm and its catalytic conversion of rare ginsenoside PPD

Lyophilization to enable distribution of ChAdOx1 and ChAdOx2 adenovirus-vectored vaccines without refrigeration

Paul Dalby Information

University

Position

___

Citations(all)

4229

Citations(since 2020)

1516

Cited By

3213

hIndex(all)

37

hIndex(since 2020)

22

i10Index(all)

80

i10Index(since 2020)

53

Email

University Profile Page

University College London

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Paul Dalby Skills & Research Interests

Therapeutic protein engineering

ability and formulation. Enzyme engineering.

Top articles of Paul Dalby

Title

Journal

Author(s)

Publication Date

Two-substrate enzyme engineering using small libraries that combine the substrate preferences from two different variant lineages

Scientific Reports

Arka Mukhopadhyay

Kersti Karu

Paul A Dalby

2024/1/14

Plasmin Cleavage of Beta-2-Glycoprotein I Alters its Structure and Ability to Bind to Pathogenic Antibodies

medRxiv

Hannah F Bradford

Christophe Lalaurie

Jayesh Gor

Xin Gao

Charis Pericleous

...

2024

A transaminase-mediated aldol reaction and applications in cascades to styryl pyridines

Catalysis Science & Technology

Yu Wang

Yiwen Li

Yeke Ni

Dejan-Krešimir Bučar

Paul A Dalby

...

2024

Investigation of the Solid-State Interactions in Lyophilized Human G-CSF Using Hydrogen–Deuterium Exchange Mass Spectrometry

Molecular Pharmaceutics

Victoria E Wood

Mark-Adam Kellerman

Kate Groves

Milena Quaglia

Elizabeth M Topp

...

2024/3/22

Machine learning integrating protein structure, sequence, and dynamics to predict the enzyme activity of bovine enterokinase variants

Journal of Chemical Information and Modeling

Niccolo Alberto Elia Venanzi

Andrea Basciu

Attilio Vittorio Vargiu

Alexandros Kiparissides

Paul A Dalby

...

2024/2/22

Time-resolved method of protein analysis

2023/1/5

Enhancement of thermal stability of Bacillus subtilis 168 glycosyltransferase YjiC based on PoPMuSiC algorithm and its catalytic conversion of rare ginsenoside PPD

Process Biochemistry

Hua Guo

Weina Li

Chenhui Zhu

Yanru Chen

Paul A Dalby

...

2023/9/1

Lyophilization to enable distribution of ChAdOx1 and ChAdOx2 adenovirus-vectored vaccines without refrigeration

npj Vaccines

Cheng Zhang

Adam Berg

Carina CD Joe

Paul A Dalby

Alexander D Douglas

2023/6/5

Challenges in scaling up AAV-based gene therapy manufacturing

Ziyu Jiang

Paul A Dalby

2023/4/30

pH-dependent crystal structures of a humanised therapeutic antibody Fab fragment: impact on molecular dynamics simulations and comparison to solution structures

Jiazhi Tang

Cheng Zhang

Nuria Codina Castillo

Christophe Lalaurie

Xin Gao

...

2023/4/18

Column-free optical deconvolution of intrinsic fluorescence for a monoclonal antibody and its product-related impurities

Journal of Chromatography A

Deniz Uçan

John E Hales

Samir Aoudjane

Nathan Todd

Paul A Dalby

2023/11/22

Enhanced thermal stability and reduced aggregation in an antibody Fab fragment at elevated concentrations

Molecular Pharmaceutics

Cheng Zhang

Jordan W Bye

Lok H Lui

Hongyu Zhang

John Hales

...

2023/4/11

Residue Effect-Guided Design: Engineering of S. Solfataricus β-Glycosidase to Enhance Its Thermostability and Bioproduction of Ginsenoside Compound K

Journal of Agricultural and Food Chemistry

Wenfeng Shen

Paul A Dalby

Zheng Guo

Weina Li

Chenhui Zhu

...

2023/10/9

Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E

Journal of Structural Biology

Christophe J Lalaurie

Andrew Splevins

Teresa S Barata

Karen A Bunting

Daniel R Higazi

...

2022/9/1

Assessing and Engineering Antibody Stability Using Experimental and Computational Methods

Cheng Zhang

Paul Anthony Dalby

2022/11/9

NMR Reveals Functionally Relevant Thermally Induced Structural Changes within the Native Ensemble of G-CSF

Molecular Pharmaceutics

Mark-Adam W Kellerman

Teresa Almeida

Timothy R Rudd

Paul Matejtschuk

Paul A Dalby

2022/8/10

Directed evolution for soluble and active periplasmic expression of bovine enterokinase in Escherichia coli

Scientific Reports

Weiluo Lee

Subhas Pradhan

Cheng Zhang

Niccolo AE Venanzi

Weina Li

...

2022/10/21

Engineering of enzymes using non-natural amino acids

Yiwen Li

Paul A Dalby

2022/8

The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer

bioRxiv

Jiazhi Tang

Cheng Zhang

Paul Dalby

Frank Kozielski

2022/6/21

Stability convergence in antibody coformulations

Molecular Pharmaceutics

Hongyu Zhang

Paul A Dalby

2022/10/20

See List of Professors in Paul Dalby University(University College London)