P. D. Allen

P. D. Allen

Harvard University

H-index: 73

North America-United States

About P. D. Allen

P. D. Allen, With an exceptional h-index of 73 and a recent h-index of 27 (since 2020), a distinguished researcher at Harvard University, specializes in the field of Ryanodine receptor, malignant hyperthermia, molecular biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Cryo-EM analysis of the malignant hyperthermia-causing T4826I mutant of ryanodine receptor 1 and its interplay with pharmacological agents

Post-Anesthesia Cognitive Dysfunction in Mice Is Associated with an Age-Related Increase in Neuronal Intracellular [Ca2+]—Neuroprotective Effect of Reducing Intracellular …

Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1)

Polysomnogram outcomes in patients with laryngomalacia and obstructive sleep apnoea treated surgically versus non-surgically

Putative malignant hyperthermia mutation CaV1. 1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance

The mechanical properties of in situ canine skeletal muscle

Aberrations in T cell calcium signaling and mitochondrial function predict the presence of the gain-of-function mutation in the ryanodine receptor type 1

The Cav1. 1 p. T1009K variant is a novel pathogenic variant for malignant hyperthermia

P. D. Allen Information

University

Position

Professor of Anaesthesia, Emeritus, Harvard Medical School

Citations(all)

19195

Citations(since 2020)

3068

Cited By

17199

hIndex(all)

73

hIndex(since 2020)

27

i10Index(all)

200

i10Index(since 2020)

99

Email

University Profile Page

Google Scholar

P. D. Allen Skills & Research Interests

Ryanodine receptor

malignant hyperthermia

molecular biology

Top articles of P. D. Allen

Title

Journal

Author(s)

Publication Date

Cryo-EM analysis of the malignant hyperthermia-causing T4826I mutant of ryanodine receptor 1 and its interplay with pharmacological agents

Biophysical Journal

Yu S Chen

Maricela García-Castañeda

Paul D Allen

Filip Van Petegem

2024/2/8

Post-Anesthesia Cognitive Dysfunction in Mice Is Associated with an Age-Related Increase in Neuronal Intracellular [Ca2+]—Neuroprotective Effect of Reducing Intracellular …

Cells

Arkady Uryash

Alfredo Mijares

Carlos E Lopez

Jose A Adams

Paul D Allen

...

2024/1/31

Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1)

bioRxiv

Thomas T Joseph

Weiming Bu

Omid Haji-Ghassemi

Yu Seby Chen

Kellie Woll

...

2024

Polysomnogram outcomes in patients with laryngomalacia and obstructive sleep apnoea treated surgically versus non-surgically

The Journal of Laryngology & Otology

Nicolas J Casellas

Shalini Shah

Saiganesh Ravikumar

Nathan D Vandjelovic

John Faria

...

2024/4

Putative malignant hyperthermia mutation CaV1. 1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance

Journal of Biological Chemistry

Wei Feng

Jose R Lopez

Shane Antrobus

Jing Zheng

Arkady Uryash

...

2023/8/1

The mechanical properties of in situ canine skeletal muscle

Frontiers in Physiology

PD Allen

JK Barclay

2022/6/6

Aberrations in T cell calcium signaling and mitochondrial function predict the presence of the gain-of-function mutation in the ryanodine receptor type 1

Biophysical Journal

Lukun Yang

Elena N Dedkova

Paul D Allen

Mohsin S Jafri

Alla F Fomina

2022/2/11

The Cav1. 1 p. T1009K variant is a novel pathogenic variant for malignant hyperthermia

British Journal of Anaesthesia

Vikas Kaura

Xiaochen Liu

Christine Diggle

Paul D Allen

Philip M Hopkins

2022/2/1

Expression of Concern: RyR1 and RyR3 isoforms provide distinct intracellular Ca2+ signals in HEK 293 cells

Journal of cell science

Daniela Rossi

Ilenia Simeoni

Marcella Micheli

Martin Bootman

Peter Lipp

...

2022/12/15

Senescence Is Associated With Elevated Intracellular Resting [Ca2+] in Mice Skeletal Muscle Fibers. An in vivo Study

Frontiers in Physiology

Alfredo Mijares

Paul D Allen

Jose R Lopez

2021/1/12

Senescence Elevated Intracellular Is Associated Resting With [Ca2+] in Mice Skeletal Muscle Fibers. An in vivo Study

Calcium Homeostasis in Skeletal Muscle Function, Plasticity and Disease

Alfredo Mijares

Paul D Allen

Jose R Lopez

2021/5/28

T lymphocytes from malignant hyperthermia-susceptible mice display aberrations in intracellular calcium signaling and mitochondrial function

Cell Calcium

Lukun Yang

Elena N Dedkova

Paul D Allen

M Saleet Jafri

Alla F Fomina

2021/1/1

The Malignant Hyperthermia G2435R Mutation Causes Constitutive RYR1 Openings

Biophysical Journal

Thomas M Humberstone

Chris Lindsay

Abigail D Wilson

Elisa Venturi

Ahmed Alhussni

...

2021/2/12

Exposure-Response Relationship of Tranexamic Acid in Cardiac Surgery A Model-based Meta-analysis

ANESTHESIOLOGY

Jose Rafael Lopez

Arkady Uryash

Jose Adams

Philip M Hopkins

Paul D Allen

2021/2/1

Ryanodine receptor leak triggers fiber Ca2+ redistribution to preserve force and elevate basal metabolism in skeletal muscle

Science Advances

Cedric R Lamboley

Luke Pearce

Crystal Seng

Aldo Meizoso-Huesca

Daniel P Singh

...

2021/10/27

Microbiomics of irrigation with xylitol or Lactococcus lactis in chronic rhinosinusitis

Laryngoscope Investigative Otolaryngology

Paul A Lambert

Ann L Gill

Steven R Gill

Paul D Allen

Li‐Xing Man

2021/2

A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke

Nature communications

Toshiko Yamazawa

Takuya Kobayashi

Nagomi Kurebayashi

Masato Konishi

Satoru Noguchi

...

2021/7/13

Molecular modification of transient receptor potential canonical 6 channels modulates calcium dyshomeostasis in a mouse model relevant to malignant hyperthermia

ANESTHESIOLOGY

Brian M Ilfeld

James C Eisenach

Rodney A Gabriel

2021/2/1

Unravelling the unseen metabolic changes in patients with malignant hyperthermia

Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Vikas Kaura

Leon Chang

Paul D Allen

2021/6

Memory and Learning Deficits Are Associated With Ca2+ Dyshomeostasis in Normal Aging

Frontiers in Aging Neuroscience

Arkady Uryash

Valentina Flores

Jose A Adams

Paul D Allen

Jose R Lopez

2020/7/16

See List of Professors in P. D. Allen University(Harvard University)

Co-Authors

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