Ozgur Sahin

Ozgur Sahin

University of South Carolina

H-index: 33

North America-United States

About Ozgur Sahin

Ozgur Sahin, With an exceptional h-index of 33 and a recent h-index of 27 (since 2020), a distinguished researcher at University of South Carolina, specializes in the field of breast cancer, drug resistance, metastasis, signaling pathways, drug discovery.

His recent articles reflect a diverse array of research interests and contributions to the field:

Targeting TACC3 induces immunogenic cell death and enhances T-DM1 response in HER2-positive breast cancer

Transcriptome analysis of polyploid giant cancer cells and their progeny reveals a functional role for p21 in polyploidization and depolyploidization

Novel bi-thiazole LOX inhibitors to overcome chemotherapy resistance in triple negative breast cancer

Inhibition of TACC3 blocks the growth of highly aggressive breast cancers with centrosome amplification

Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer

Overcoming tamoxifen resistance by re-activating cAMP-Ca2+−ROS-ferroptosis axis in ER+ breast cancer

Cholesterol biogenesis is a PTEN‐dependent actionable node for the treatment of endocrine therapy‐refractory cancers

Abstract P4-08-20: Inhibition of TACC3 blocks the growth of highly aggressive breast cancers with centrosome amplification

Ozgur Sahin Information

University

Position

Associate Professor at

Citations(all)

17012

Citations(since 2020)

7767

Cited By

10416

hIndex(all)

33

hIndex(since 2020)

27

i10Index(all)

52

i10Index(since 2020)

43

Email

University Profile Page

University of South Carolina

Google Scholar

View Google Scholar Profile

Ozgur Sahin Skills & Research Interests

breast cancer

drug resistance

metastasis

signaling pathways

drug discovery

Top articles of Ozgur Sahin

Title

Journal

Author(s)

Publication Date

Targeting TACC3 induces immunogenic cell death and enhances T-DM1 response in HER2-positive breast cancer

Cancer Research

Mustafa Emre Gedik

Ozge Saatci

Nathaniel Oberholtzer

Meral Uner

Ozge Akbulut-Caliskan

...

2024/2/6

Transcriptome analysis of polyploid giant cancer cells and their progeny reveals a functional role for p21 in polyploidization and depolyploidization

Journal of Biological Chemistry

Shai White-Gilbertson

Ping Lu

Ozge Saatci

Ozgur Sahin

Joe R Delaney

...

2024/4/1

Novel bi-thiazole LOX inhibitors to overcome chemotherapy resistance in triple negative breast cancer

Cancer Research

Metin Cetin

Ozge Saatci

Abdol-Hossein Rezaeian

Ozge Akbulut

Nageswara Rao Chintada

...

2023/4/4

Inhibition of TACC3 blocks the growth of highly aggressive breast cancers with centrosome amplification

Cancer Research

Ozge Saatci

Ozge Akbulut

Metin Cetin

Vitali Sikirzhytski

Ozgur Sahin

2023/4/4

Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer

Nature Communications

Ozge Saatci

Metin Cetin

Meral Uner

Unal Metin Tokat

Ioulia Chatzistamou

...

2023/11/2

Overcoming tamoxifen resistance by re-activating cAMP-Ca2+−ROS-ferroptosis axis in ER+ breast cancer

Cancer Research

Rashedul Alam

Ozge Saatci

Meral Bugadyci Uner

Kim-Tuyen Huynh-Dam

Metin Cetin

...

2023/4/4

Cholesterol biogenesis is a PTEN‐dependent actionable node for the treatment of endocrine therapy‐refractory cancers

Cancer Science

Irmak Kaysudu

Taha Bugra Gungul

Sena Atici

Sevval Yilmaz

Engin Bayram

...

2023/11

Abstract P4-08-20: Inhibition of TACC3 blocks the growth of highly aggressive breast cancers with centrosome amplification

Cancer Research

Ozge Saatci

Ozge Akbulut

Metin Cetin

Vitali Sikirzhytski

Ozgur Sahin

2023/3/1

Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification

Cell Death & Differentiation

Ozge Saatci

Ozge Akbulut

Metin Cetin

Vitali Sikirzhytski

Meral Uner

...

2023/5

Abstract P6-10-18: Developing novel lysyl oxidase (LOX) inhibitors to overcome chemotherapy resistance in triple negative breast cancer

Cancer Research

Metin Cetin

Ozge Saatci

Ozge Akbulut

Chad Beneker

Abdol-Hossein Rezaeian

...

2023/3/1

Highly potent TACC3 inhibitor as a novel anticancer drug candidate

2023/4/11

Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis

Cell reports

Alhaji H Janneh

Mohamed Faisal Kassir

F Cansu Atilgan

Han Gyul Lee

Megan Sheridan

...

2022/12/6

miR-489 confines uncontrolled estrogen signaling through a negative feedback mechanism and regulates tamoxifen resistance in breast cancer

International Journal of Molecular Sciences

Mithil Soni

Ozge Saatci

Gourab Gupta

Yogin Patel

Manikanda Raja Keerthi Raja

...

2022/7/22

Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer

Breast cancer research and treatment

Ridho Assidicky

Unal Metin Tokat

Ibrahim Oguzhan Tarman

Ozge Saatci

Pelin Gulizar Ersan

...

2022/6

HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin

Oncogene

Marco Biondini

Alex Kiepas

Leeanna El-Houjeiri

Matthew G Annis

Brian E Hsu

...

2022/3/18

EGF-SNX3-EGFR axis drives tumor progression and metastasis in triple-negative breast cancers

Oncogene

Esra Cicek

Ayca Circir

Merve Oyken

Ozge Akbulut Caliskan

Didem Naz Dioken

...

2022/1/5

Abstract LT015: Overcoming chemotherapy resistance in triple negative breast cancer via targeting lysyl oxidase (LOX)

Cancer Research

Ozge Saatci

Ozge Akbulut

Abdol-Hossein Rezaeain

Carolyn Banister

Vitali Sikirzhytski

...

2021/3/1

Coordinated regulation of WNT/β-catenin, c-Met, and integrin signalling pathways by miR-193b controls triple negative breast cancer metastatic traits

BMC cancer

Chiara Giacomelli

Janine Jung

Astrid Wachter

Susanne Ibing

Rainer Will

...

2021/12

Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer

British journal of cancer

Mohammad Aarif Siddiqui

Paradesi Naidu Gollavilli

Vignesh Ramesh

Beatrice Parma

Annemarie Schwab

...

2021/1/5

Endocrine resistance in breast cancer: from molecular mechanisms to therapeutic strategies

Ozge Saatci

Kim-Tuyen Huynh-Dam

Ozgur Sahin

2021/12

See List of Professors in Ozgur Sahin University(University of South Carolina)