Ondřej Benek

Ondřej Benek

Univerzita Hradec Králové

H-index: 15

Europe-Czech Republic

About Ondřej Benek

Ondřej Benek, With an exceptional h-index of 15 and a recent h-index of 15 (since 2020), a distinguished researcher at Univerzita Hradec Králové, specializes in the field of medicinal chemistry, drug development.

His recent articles reflect a diverse array of research interests and contributions to the field:

Nanomolar Benzothiazole-Based Inhibitors of 17β-HSD10 with Cellular Bioactivity

Development of Submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation

Physiologically relevant fluorescent assay for identification of 17β‐hydroxysteroid dehydrogenase type 10 inhibitors

Small‐molecule inhibitors of cyclophilin D as potential therapeutics in mitochondria‐related diseases

Effects of novel 17β-hydroxysteroid dehydrogenase type 10 inhibitors on mitochondrial respiration

RNase T1 Refolding Assay for Determining Mitochondrial Cyclophilin D Activity: A Novel In Vitro Method Applicable in Drug Research and Discovery

SEARCHING FOR NEW ANTIMICROBIAL AGENTS BY TARGETING BACTERIAL NAD METABOLISM: EVALUATION OF FRENTIZOLE DERIVATIVES SELECTED BY MOLECULAR DOCKING.

Friend or enemy? Review of 17β‐HSD10 and its role in human health or disease

Ondřej Benek Information

University

Position

postdoctoral fellow

Citations(all)

662

Citations(since 2020)

545

Cited By

292

hIndex(all)

15

hIndex(since 2020)

15

i10Index(all)

18

i10Index(since 2020)

17

Email

University Profile Page

Univerzita Hradec Králové

Google Scholar

View Google Scholar Profile

Ondřej Benek Skills & Research Interests

medicinal chemistry

drug development

Top articles of Ondřej Benek

Title

Journal

Author(s)

Publication Date

Nanomolar Benzothiazole-Based Inhibitors of 17β-HSD10 with Cellular Bioactivity

ACS Medicinal Chemistry Letters

Michaela Hanzlova

Marketa Sedlacek Miskerikova

Aneta Rotterova

Katarina Chalupova

Katarina Jurkova

...

2023/11/10

Development of Submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation

European Journal of Medicinal Chemistry

Ondrej Benek

Michaela Vaskova

Marketa Miskerikova

Monika Schmidt

Rudolf Andrys

...

2023/10/5

Physiologically relevant fluorescent assay for identification of 17β‐hydroxysteroid dehydrogenase type 10 inhibitors

Journal of Neurochemistry

Monika Schmidt

Michaela Vaskova

Aneta Rotterova

Pavlina Fiandova

Marketa Miskerikova

...

2023/10

Small‐molecule inhibitors of cyclophilin D as potential therapeutics in mitochondria‐related diseases

Annamaria Haleckova

Ondrej Benek

Lucie Zemanová

Rafael Dolezal

Kamil Musilek

2022/9

Effects of novel 17β-hydroxysteroid dehydrogenase type 10 inhibitors on mitochondrial respiration

Toxicology Letters

Zdeněk Fišar

Kamil Musílek

Ondřej Benek

Lukáš Hroch

Lucie Vinklářová

...

2021/3/15

RNase T1 Refolding Assay for Determining Mitochondrial Cyclophilin D Activity: A Novel In Vitro Method Applicable in Drug Research and Discovery

Biochemistry

Lucie Zemanova

Michaela Vaskova

Monika Schmidt

Jana Roubalova

Annamaria Haleckova

...

2020/4/10

SEARCHING FOR NEW ANTIMICROBIAL AGENTS BY TARGETING BACTERIAL NAD METABOLISM: EVALUATION OF FRENTIZOLE DERIVATIVES SELECTED BY MOLECULAR DOCKING.

Military Medical Science Letters/Vojenské Zdravotnické Listy

Michaela Hympanova

Tomas Kucera

Ondrej Benek

Jan Korabecny

Jan Marek

2020/4/1

Friend or enemy? Review of 17β‐HSD10 and its role in human health or disease

Lucie Vinklarova

Monika Schmidt

Ondrej Benek

Kamil Kuca

Frank Gunn‐Moore

...

2020/11

Benzothiazolyl ureas are low micromolar and uncompetitive inhibitors of 17β-HSD10 with implications to Alzheimer’s disease treatment

International Journal of Molecular Sciences

Monika Schmidt

Ondrej Benek

Lucie Vinklarova

Martina Hrabinova

Lucie Zemanova

...

2020/3/17

Exploring the chemical space of benzothiazole-based DNA gyrase B inhibitors

ACS medicinal chemistry letters

Žiga Skok

Michaela Barančoková

Ondřej Benek

Cristina Durante Cruz

Päivi Tammela

...

2020/10/15

Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile

European journal of medicinal chemistry

Katerina Sobolova

Martina Hrabinova

Vendula Hepnarova

Tomas Kucera

Tereza Kobrlova

...

2020/10/1

A perspective on multi-target drugs for Alzheimer’s disease

Ondrej Benek

Jan Korabecny

Ondrej Soukup

2020/7/1

See List of Professors in Ondřej Benek University(Univerzita Hradec Králové)