Nieng Yan

Nieng Yan

Princeton University

H-index: 67

North America-United States

About Nieng Yan

Nieng Yan, With an exceptional h-index of 67 and a recent h-index of 53 (since 2020), a distinguished researcher at Princeton University, specializes in the field of membrane transport, Cav/Nav channels, transporters, cholesterol metabolism.

His recent articles reflect a diverse array of research interests and contributions to the field:

Structural basis for human Cav3.2 inhibition by selective antagonists

Structure-guided discovery of protein and glycan components in native mastigonemes

Structural basis for different ω-agatoxin IVA sensitivities of the P-type and Q-type Cav2.1 channels

Dissection of the structure–function relationship of Nav channels

Structural biology of voltage-gated calcium channels

A structural atlas of druggable sites on Nav channels

Dual-pocket inhibition of Nav channels by the antiepileptic drug lamotrigine

Cryo-EM structure of human voltage-gated sodium channel Nav1.6

Nieng Yan Information

University

Position

___

Citations(all)

17365

Citations(since 2020)

9719

Cited By

11442

hIndex(all)

67

hIndex(since 2020)

53

i10Index(all)

114

i10Index(since 2020)

103

Email

University Profile Page

Princeton University

Google Scholar

View Google Scholar Profile

Nieng Yan Skills & Research Interests

membrane transport

Cav/Nav channels

transporters

cholesterol metabolism

Top articles of Nieng Yan

Title

Journal

Author(s)

Publication Date

Structural basis for human Cav3.2 inhibition by selective antagonists

Cell Research

Jian Huang

Xiao Fan

Xueqin Jin

Chen Lyu

Qinmeng Guo

...

2024/4/11

Structure-guided discovery of protein and glycan components in native mastigonemes

Cell

Junhao Huang

Hui Tao

Jikun Chen

Yang Shen

Jianlin Lei

...

2024/3/28

Structural basis for different ω-agatoxin IVA sensitivities of the P-type and Q-type Cav2.1 channels

Cell Research

Zhangqiang Li

Ye Cong

Tong Wu

Tongtong Wang

Xinyao Lou

...

2024/3/5

Dissection of the structure–function relationship of Nav channels

Proceedings of the National Academy of Sciences

Zhangqiang Li

Qiurong Wu

Gaoxingyu Huang

Xueqin Jin

Jiaao Li

...

2024/2/27

Structural biology of voltage-gated calcium channels

Xia Yao

Shuai Gao

Nieng Yan

2024/12/31

A structural atlas of druggable sites on Nav channels

Zhangqiang Li

Qiurong Wu

Nieng Yan

2024/12/31

Dual-pocket inhibition of Nav channels by the antiepileptic drug lamotrigine

Proceedings of the National Academy of Sciences

Jian Huang

Xiao Fan

Xueqin Jin

Liming Teng

Nieng Yan

2023/10/10

Cryo-EM structure of human voltage-gated sodium channel Nav1.6

Proceedings of the National Academy of Sciences

Xiao Fan

Jian Huang

Xueqin Jin

Nieng Yan

2023/1/31

Addressing preferred orientation in single-particle cryo-EM through AI-generated auxiliary particles

arXiv preprint arXiv:2309.14954

Hui Zhang

Dihan Zheng

Qiurong Wu

Nieng Yan

Zuoqiang Shi

...

2023/9/26

Cannabidiol inhibits Nav channels through two distinct binding sites

Nature Communications

Jian Huang

Xiao Fan

Xueqin Jin

Sooyeon Jo

Hanxiong Bear Zhang

...

2023/6/17

Structural mapping of Nav1.7 antagonists

Nature Communications

Qiurong Wu

Jian Huang

Xiao Fan

Kan Wang

Xueqin Jin

...

2023/6/3

High-speed AFM imaging of voltage gated sodium channel NaChBac and voltage application

Biophysical Journal

Motonori Imamura

Atsushi Miyagi

Shuai Gao

Nieng Yan

Simon Scheuring

2023/2/10

Structural basis for human Cav1. 2 inhibition by multiple drugs and the neurotoxin calciseptine

Cell

Shuai Gao

Xia Yao

Jiaofeng Chen

Gaoxingyu Huang

Xiao Fan

...

2023/11/22

Cryo-EM structure supports a role of AQP7 as a junction protein

Nature Communications

Peng Huang

Raminta Venskutonytė

Rashmi B Prasad

Hamidreza Ardalani

Sofia W de Maré

...

2023/2/3

Molecular basis for inhibiting human glucose transporters by exofacial inhibitors

Nature communications

Nan Wang

Shuo Zhang

Yafei Yuan

Hanwen Xu

Elisabeth Defossa

...

2022/5/12

Profile of Nieng Yan

Proceedings of the National Academy of Sciences

Sandeep Ravindran

2022/8/16

High-resolution structures of human Nav1. 7 reveal gating modulation through α-π helical transition of S6IV

Cell Reports

Gaoxingyu Huang

Dongliang Liu

Weipeng Wang

Qiurong Wu

Jiaofeng Chen

...

2022/4/26

INAUGURAL ARTICLE by a Recently Elected Academy Member: Unwinding and spiral sliding of S4 and domain rotation of VSD during the electromechanical coupling in Nav1. 7

Proceedings of the National Academy of Sciences of the United States of America

Tori M Hoehler

Dylan J Mankel

Peter R Girguis

Thomas M McCollom

Nancy Y Kiang

...

2023/6/6

Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels

Cell

Xia Yao

Shuai Gao

Jixin Wang

Zhangqiang Li

Jian Huang

...

2022/12/8

Structural advances in sterol-sensing domain-containing proteins

Xuelan Wu

Renhong Yan

Pingping Cao

Hongwu Qian

Nieng Yan

2022/1/7

See List of Professors in Nieng Yan University(Princeton University)

Co-Authors

H-index: 123
Yigong Shi

Yigong Shi

Tsinghua University

H-index: 55
Jiawei Wang

Jiawei Wang

Tsinghua University

H-index: 21
Shuai Gao

Shuai Gao

Princeton University

H-index: 14
Dong Deng

Dong Deng

Sichuan University

H-index: 9
Xiao Fan

Xiao Fan

Princeton University

H-index: 9
Xia Yao

Xia Yao

Princeton University

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