Nick Haining

Nick Haining

Harvard University

H-index: 54

North America-United States

About Nick Haining

Nick Haining, With an exceptional h-index of 54 and a recent h-index of 44 (since 2020), a distinguished researcher at Harvard University, specializes in the field of immunology, systems biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Modulating dsRNA editing, sensing, and metabolism to increase tumor immunity and improve the efficacy of cancer immunotherapy and/or modulators of intratumoral interferon

X-CHIME enables combinatorial, inducible, lineage-specific and sequential knockout of genes in the immune system

Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion

Overcoming resistance to immunotherapy due to loss of antigen presentation

Targeting mammalian SWI/SNF chromatin remodeling complexes to improve T cell-based cancer immunotherapies

Multiplexed shRNA cassettes targeting orthogonal pathways (FAS/PTPN2/TGFBR) enhance the potency of integrated circuit T cells (ICTs) in multiple solid tumor models

Modulating biomarkers to increase tumor immunity and improve the efficacy of cancer immunotherapy

In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer

Nick Haining Information

University

Position

Assistant Professor, Harvard Medical School

Citations(all)

22102

Citations(since 2020)

14036

Cited By

13448

hIndex(all)

54

hIndex(since 2020)

44

i10Index(all)

73

i10Index(since 2020)

64

Email

University Profile Page

Google Scholar

Nick Haining Skills & Research Interests

immunology

systems biology

Top articles of Nick Haining

Title

Journal

Author(s)

Publication Date

Modulating dsRNA editing, sensing, and metabolism to increase tumor immunity and improve the efficacy of cancer immunotherapy and/or modulators of intratumoral interferon

2024/1/16

X-CHIME enables combinatorial, inducible, lineage-specific and sequential knockout of genes in the immune system

Nature Immunology

Martin W LaFleur

Ashlyn M Lemmen

Ivy SL Streeter

Thao H Nguyen

Lauren E Milling

...

2024/1

Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion

Molecular cell

Elena Battistello

Kimberlee A Hixon

Dawn E Comstock

Clayton K Collings

Xufeng Chen

...

2023/4/20

Overcoming resistance to immunotherapy due to loss of antigen presentation

Cancer Research

Brian C Miller

Yacine Choutri

Rose Al Abosy

Amy Huang

Emily K Cox

...

2023/4/4

Targeting mammalian SWI/SNF chromatin remodeling complexes to improve T cell-based cancer immunotherapies

Cancer Research

Elena Battistello

Kimberlee Hixon

Dawn E Comstock

Clayton K Collings

Xufeng Chen

...

2023/4/4

Multiplexed shRNA cassettes targeting orthogonal pathways (FAS/PTPN2/TGFBR) enhance the potency of integrated circuit T cells (ICTs) in multiple solid tumor models

Cancer Research

Thomas J Gardner

Adam Litterman

Brenal K Singh

Luisa Silva

Mukund Hari

...

2023/4/4

Modulating biomarkers to increase tumor immunity and improve the efficacy of cancer immunotherapy

2020/9/24

In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer

Nature Immunology

Juan Dubrot

Peter P Du

Sarah Kate Lane-Reticker

Emily A Kessler

Audrey J Muscato

...

2022/10

Batf-mediated epigenetic control of effector CD8+ T cell differentiation

Science Immunology

Hsiao-Wei Tsao

James Kaminski

Makoto Kurachi

R. Anthony Barnitz

Michael A. DiIorio

...

2022/3/17

Multiplexed shRNAs targeting FAS and PTPN2 enhance CAR T persistence and anti-tumor efficacy

Cancer Research

John Gagnon

Adam J Litterman

Jason A Hall

Dina Polyak

Stanley Zhou

...

2022/6/15

Improved vector systems for cas protein and sgrna delivery, and uses therefor

2022/1/20

Retention of epigenetic and transcriptional memory among reprogrammed T cells (T-iPSCs) imparts selective advantage for T cell re-differentiation.

The Journal of Immunology

Robin L Williams

Alyssa Morrow

Jeremy Allred

Jakub Tolar

W Nicholas Haining

...

2022/5/1

PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment

Journal for ImmunoTherapy of Cancer

Natalie B Collins

Rose Al Abosy

Brian C Miller

Kevin Bi

Qihong Zhao

...

2022

Modulating ptpn2 to increase immune responses and perturbing gene expression in hematopoietic stem cell lineages

2022/3/17

When cancer cells become the enablers of an antitumor immune response

Cancer Discovery

Antoni Ribas

W Nicholas Haining

Ton NM Schumacher

2022/10/5

Modulating biomarkers such as spp to increase tumor immunity and improve the efficacy of cancer immunotherapy

2022/2/24

T-cell exhaustion state-specific gene expression regulators and uses thereof

2021/10/7

Epigenetic features of HIV-induced T-cell exhaustion persist despite early antiretroviral therapy

Frontiers in immunology

Genevieve E Martin

Debattama R Sen

Matthew Pace

Nicola Robinson

Jodi Meyerowitz

...

2021/6/4

In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma

Immunity

Juan Dubrot

Sarah Kate Lane-Reticker

Emily A Kessler

Austin Ayer

Gargi Mishra

...

2021/3/9

Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans

Nature immunology

Kathleen B Yates

Pierre Tonnerre

Genevieve E Martin

Ulrike Gerdemann

Rose Al Abosy

...

2021/8

See List of Professors in Nick Haining University(Harvard University)