Nicholas Levinson
University of Minnesota-Twin Cities
H-index: 16
North America-United States
Top articles of Nicholas Levinson
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Screening through lead optimization of high affinity, allosteric cyclin-dependent kinase 2 (CDK2) inhibitors as male contraceptives that reduce sperm counts in mice | Journal of medicinal chemistry | Erik B Faber Nan Wang Kristen John Luxin Sun Henry L Wong | 2023/1/26 |
Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding | Nature communications | Erik B Faber Luxin Sun Jian Tang Emily Roberts Sornakala Ganeshkumar | 2023/6/3 |
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors | bioRxiv | Damien M Rasmussen Manny M Semonis Joseph T Greene Joseph M Muretta Andrew R Thompson | 2023/4/19 |
Thermodynamic and allosteric basis of paradoxical activation in V600E BRAF cancers | Biophysical Journal | Damien Rasmussen Manny Semonis Nicholas Levinson | 2022/2/11 |
The discovery of high affinity and metabolically stable allosteric cyclin-dependent kinase 2 (CDK2) inhibitors from screening through lead optimization | Erik B Faber Nan Wang Kristen John Luxin Sun David Burban | 2022/8/18 | |
Development of allosteric, selective cyclin-dependent kinase 2 (CDK2) inhibitors that are negatively cooperative with cyclin binding and show potential as contraceptive agents | bioRxiv | Erik B Faber Jian Tang Emily Roberts Sornakala Ganeshkumar Luxin Sun | 2022/7/2 |
Targeting N-Myc in neuroblastoma cells with selective Aurora kinase A degraders | Cancer Research | Jian Tang Ramkumar Moorthy Ozlem Demir Zachary D Baker Jordan A Naumann | 2022/6/15 |
Targeting N-myc in neuroblastoma with selective aurora kinase A degraders | bioRxiv | Jian Tang Ramkumar Moorthy Özlem Demir Zachary D Baker Jordan A Naumann | 2022/4/10 |
Protein kinase allostery sensor and methods of making and using same | 2021/8/24 | ||
Allostery governs Cdk2 activation and differential recognition of CDK inhibitors | Nature chemical biology | Abir Majumdar David J Burban Joseph M Muretta Andrew R Thompson Tiffany A Engel | 2021/4 |
Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry | Nature communications | N Tavernier Y Thomas S Vigneron P Maisonneuve S Orlicky | 2021/3/26 |
Cooperativity between orthosteric inhibitors and allosteric inhibitor 8-anilino-1-naphthalene sulfonic acid (ANS) in cyclin-dependent kinase 2 | ACS chemical biology | Erik B Faber Defeng Tian David Burban Nicholas M Levinson Jon E Hawkinson | 2020/5/20 |
Discovery of CDK2 allosteric inhibitors for male contraception and anticancer therapy | American Chemical Society SciMeetings | Gunda Georg Erik Faber Jon Hawkinson Nan Wang David Burban | 2020/8/17 |
