Nicholas Kirkby

Nicholas Kirkby

Imperial College London

H-index: 30

Europe-United Kingdom

About Nicholas Kirkby

Nicholas Kirkby, With an exceptional h-index of 30 and a recent h-index of 25 (since 2020), a distinguished researcher at Imperial College London, specializes in the field of Cardiovascular, Pharmacology, Eicosanoids.

His recent articles reflect a diverse array of research interests and contributions to the field:

L-arginine supplementation protects against thrombosis and renal dysfunction in mice treated with the cyclooxygenase-2 inhibitor parecoxib

Widening the prostacyclin paradigm: tissue fibroblasts are a critical site of production and antithrombotic protection

Renal function underpins the cyclooxygenase-2: asymmetric dimethylarginine axis in mouse and man

Pulmonary Hypertension-Associated Right Ventricular Cardiomyocyte Remodelling Reduces Treprostinil Function

COX-1-derived mediators in the functional interplay between bronchi and vessels

Using Renal-Specific Cyclo-Oxygenase-2-Deficient Mice to Understand the Pro-Thrombotic Effects of Non-Steroidal Anti-Inflammatory Drugs

Activation of prostacyclin (PGI2) IP receptors by treprostinil in the right atrium is associated with stronger fibroblast PKA response

The Effects of Celecoxib on Endothelial Function in Healthy Volunteers; A Double Blind, Placebo Controlled Randomised Trial

Nicholas Kirkby Information

University

Position

Research Fellow

Citations(all)

3290

Citations(since 2020)

1909

Cited By

2347

hIndex(all)

30

hIndex(since 2020)

25

i10Index(all)

52

i10Index(since 2020)

44

Email

University Profile Page

Imperial College London

Google Scholar

View Google Scholar Profile

Nicholas Kirkby Skills & Research Interests

Cardiovascular

Pharmacology

Eicosanoids

Top articles of Nicholas Kirkby

Title

Journal

Author(s)

Publication Date

L-arginine supplementation protects against thrombosis and renal dysfunction in mice treated with the cyclooxygenase-2 inhibitor parecoxib

Journal of Thrombosis and Haemostasis

Ricky Vaja

Maria Lopes-Pires

Fisnik Shala

Neringa Cypaite

Maria Vinokurova

...

2024/3/20

Widening the prostacyclin paradigm: tissue fibroblasts are a critical site of production and antithrombotic protection

Arteriosclerosis, Thrombosis, and Vascular Biology

Maria Vinokurova

Maria Elisa Lopes-Pires

Neringa Cypaite

Fisnik Shala

Paul C Armstrong

...

2024/1

Renal function underpins the cyclooxygenase-2: asymmetric dimethylarginine axis in mouse and man

Kidney International Reports

Plinio Ferreira

Ricky Vaja

Maria Lopes-Pires

Marilena Crescente

He Yu

...

2023/6/1

Pulmonary Hypertension-Associated Right Ventricular Cardiomyocyte Remodelling Reduces Treprostinil Function

Cells

Aleksandra Judina

Marili Niglas

Vladislav Leonov

Nicholas S Kirkby

Ivan Diakonov

...

2023/12/4

COX-1-derived mediators in the functional interplay between bronchi and vessels

Ida Cerqua

Elisabetta Granato

Antonietta Rossi

Maria Lopes Pires

Nicholas Kirkby

...

2023/9/9

Using Renal-Specific Cyclo-Oxygenase-2-Deficient Mice to Understand the Pro-Thrombotic Effects of Non-Steroidal Anti-Inflammatory Drugs

Circulation

Maria Lopes Pires

Plinio Ferreira

Fisnik Shala

Neringa Cypaite

Maria Vinokurova

...

2022/11/8

Activation of prostacyclin (PGI2) IP receptors by treprostinil in the right atrium is associated with stronger fibroblast PKA response

Journal of Molecular and Cellular Cardiology

Aleksandra Judina

Austin Endo

Lan Zhao

Marili Niglas

Peter Wright

...

2022/12/31

The Effects of Celecoxib on Endothelial Function in Healthy Volunteers; A Double Blind, Placebo Controlled Randomised Trial

Circulation

Ricky Vaja

Plinio Ferreira

Peter Collins

Matthew Rickman

Prakash P Punjabi

...

2022/11/8

Temporal in vivo platelet labeling in mice reveals age-dependent receptor expression and conservation of specific mRNAs

Blood Advances

Paul C Armstrong

Harriet E Allan

Nicholas S Kirkby

Clemens Gutmann

Abhishek Joshi

...

2022/12/13

SWATH proteomic analysis from the standard care versus celecoxib outcome trial identifies renal biomarkers are associated with early cardiovascular events amongst NSAID users

European Heart Journal

R Vaja

PM Ferreira

L Want

B Ahmetaj-Shala

H Gashaw

...

2022/10/1

Tissue fibroblasts are a critical source of prostacyclin and anti-thrombotic protection

bioRxiv

Jane A Mitchell

Maria Vinokurova

Maria Elisa Lopes-Pires

Fisnik Shala

Paul C Armstrong

...

2022/1/12

Renal Function Underpins Cox-2: Methylarginine Axis in Mouse and Man

Circulation

Plinio M Ferreira

Nicholas Kirkby

Ricky Vaja

Maria Lopes Pires

Marilena Crescente

...

2022/11/8

Identifying Sources of Prostacyclin Outside the Vascular Wall and Their Contribution to Cardiovascular Protection

Circulation

Maria Lopes Pires

Maria Vinokurova

Fisnik Shala

Blerina Ahmetaj-Shala

Paul C Armstrong

...

2022/11/8

Activation and Contraction of Human “Vascular” Smooth Muscle Cells Grown From Circulating Blood Progenitors

Frontiers in Cell and Developmental Biology

Blerina Ahmetaj-Shala

Isra Marei

Ryota Kawai

Stephen Rothery

Charis Pericleous

...

2021/8/23

Cyclooxygenases and the cardiovascular system

Jane A Mitchell

Nicholas S Kirkby

Blerina Ahmetaj-Shala

Paul C Armstrong

Marilena Crescente

...

2021/1/1

Differential effects of omega-3 fatty acids on lipopolysaccharide (LPS)-induced macrophage activation in combination with cox inhibition

Atherosclerosis

S Al-Asfoor

JA Mitchell

P Mason

NS Kirkby

HH Gashaw

2021/8/1

Endothelial cyclooxygenase-1 paradoxically drives local vasoconstriction and atherogenesis despite underpinning prostacyclin generation

Science Advances

Jane A Mitchell

Fisnik Shala

Maria Elisa Lopes Pires

Rachel Y Loy

Andrew Ravendren

...

2021/3/19

The COVID‐19 ibuprofen controversy: a systematic review of NSAIDs in adult acute lower respiratory tract infections

British Journal of Clinical Pharmacology

R Vaja

J Chan

P Ferreira

A Harky

LJ Rogers

...

2020

Platelet inhibition by P2Y12 antagonists is potentiated by adenosine signalling activators

British Journal of Pharmacology

Chih‐Chin Shih

Melissa V Chan

Nicholas S Kirkby

Ivana Vojnovic

Jane A Mitchell

...

2021/12

Studies on metal–organic framework (MOF) nanomedicine preparations of sildenafil for the future treatment of pulmonary arterial hypertension

Scientific Reports

Nura A Mohamed

Haissam Abou-Saleh

Yu Kameno

Isra Marei

Gilberto de Nucci

...

2021/2/22

See List of Professors in Nicholas Kirkby University(Imperial College London)