Nicholas C. Wu

Nicholas C. Wu

University of Illinois at Urbana-Champaign

H-index: 44

North America-United States

About Nicholas C. Wu

Nicholas C. Wu, With an exceptional h-index of 44 and a recent h-index of 41 (since 2020), a distinguished researcher at University of Illinois at Urbana-Champaign, specializes in the field of Influenza virus, SARS-CoV-2, antibodies, protein evolution, structural biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike

Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site

Widespread impact of immunoglobulin V-gene allelic polymorphisms on antibody reactivity

Age-related seroprevalence trajectories of seasonal coronaviruses in children including neonates in Guangzhou, China

Defining and studying B cell receptor and TCR interactions

Mutational fitness landscape of human influenza H3N2 neuraminidase

Targeting neuraminidase: the next frontier for broadly protective influenza vaccines

An explainable language model for antibody specificity prediction using curated influenza hemagglutinin antibodies

Nicholas C. Wu Information

University

Position

___

Citations(all)

10116

Citations(since 2020)

9198

Cited By

4366

hIndex(all)

44

hIndex(since 2020)

41

i10Index(all)

86

i10Index(since 2020)

80

Email

University Profile Page

University of Illinois at Urbana-Champaign

Google Scholar

View Google Scholar Profile

Nicholas C. Wu Skills & Research Interests

Influenza virus

SARS-CoV-2

antibodies

protein evolution

structural biology

Top articles of Nicholas C. Wu

Title

Journal

Author(s)

Publication Date

Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike

Timothy JC Tan

Abby Odle

Ruipeng Lei

Kenneth A Matreyek

Stanley Perlman

...

2023

Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site

Cell Host & Microbe

Andrew J Thompson

Nicholas C Wu

Angeles Canales

Chika Kikuchi

Xueyong Zhu

...

2024/2/14

Widespread impact of immunoglobulin V-gene allelic polymorphisms on antibody reactivity

Cell Reports

Meng Yuan

Ziqi Feng

Huibin Lv

Natalie So

Ivana R Shen

...

2023/10/31

Age-related seroprevalence trajectories of seasonal coronaviruses in children including neonates in Guangzhou, China

International Journal of Infectious Diseases

Yasha Luo

Huibin Lv

Shilin Zhao

Yuanxin Sun

Chengyi Liu

...

2023/2/1

Defining and studying B cell receptor and TCR interactions

The Journal of Immunology

C Garrett Rappazzo

Monica L Fernández-Quintero

Andreas Mayer

Nicholas C Wu

Victor Greiff

...

2023/8/1

Mutational fitness landscape of human influenza H3N2 neuraminidase

Cell reports

Ruipeng Lei

Andrea Hernandez Garcia

Timothy JC Tan

Qi Wen Teo

Yiquan Wang

...

2023/1/31

Targeting neuraminidase: the next frontier for broadly protective influenza vaccines

Nicholas C Wu

Ali H Ellebedy

2023/12/15

An explainable language model for antibody specificity prediction using curated influenza hemagglutinin antibodies

bioRxiv

Yiquan Wang

Huibin Lv

Ruipeng Lei

Yuen-Hei Yeung

Ivana R Shen

...

2023

Imprinted anti-hemagglutinin and anti-neuraminidase antibody responses after childhood infections of A (H1N1) and A (H1N1) pdm09 influenza viruses

MBio

Pavithra Daulagala

Brian R Mann

Kathy Leung

Eric HY Lau

Louise Yung

...

2023/6/27

Stringent and complex sequence constraints of an IGHV1-69 broadly neutralizing antibody to influenza HA stem

Cell Reports

Qi Wen Teo

Yiquan Wang

Huibin Lv

Timothy JC Tan

Ruipeng Lei

...

2023/11/28

High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike

Nature Communications

Timothy JC Tan

Zongjun Mou

Ruipeng Lei

Wenhao O Ouyang

Meng Yuan

...

2023/4/10

Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase

Immunity

Ruipeng Lei

Wooseob Kim

Huibin Lv

Zongjun Mou

Michael J Scherm

...

2023/11/14

A TLR7-nanoparticle adjuvant promotes a broad immune response against heterologous strains of influenza and SARS-CoV-2

Nature materials

Qian Yin

Wei Luo

Vamsee Mallajosyula

Yang Bo

Jing Guo

...

2023/3

Interactions between Influenza A Virus Nucleoprotein and Gene Segment Untranslated Regions Facilitate Selective Modulation of Viral Gene Expression

Journal of virology

Meghan Diefenbacher

Timothy JC Tan

David LV Bauer

Beth M Stadtmueller

Nicholas C Wu

...

2022/5/25

Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase

Nature Communications

Ruipeng Lei

Timothy JC Tan

Andrea Hernandez Garcia

Yiquan Wang

Meghan Diefenbacher

...

2022/10/28

Unlocking capacities of genomics for the COVID-19 response and future pandemics

Nature Methods

Sergey Knyazev

Karishma Chhugani

Varuni Sarwal

Ram Ayyala

Harman Singh

...

2022/4

The evolutionary potential of influenza A virus hemagglutinin is highly constrained by epistatic interactions with neuraminidase

Cell Host & Microbe

Tongyu Liu

Yiquan Wang

Timothy JC Tan

Nicholas C Wu

Christopher B Brooke

2022/10/12

Neutralizing Antibodies to SARS‐CoV‐2 Selected from a Human Antibody Library Constructed Decades Ago

Advanced Science

Min Qiang

Peixiang Ma

Yu Li

Hejun Liu

Adam Harding

...

2022/1

Egg-adaptive mutations of human influenza H3N2 virus are contingent on natural evolution

PLoS pathogens

Weiwen Liang

Timothy JC Tan

Yiquan Wang

Huibin Lv

Yuanxin Sun

...

2022/9/26

Neutralizing Antibody Response to Sarbecovirus Is Delayed in Sequential Heterologous Immunization

Viruses

Huibin Lv

Ray TY So

Qi Wen Teo

Meng Yuan

Hejun Liu

...

2022/6/24

See List of Professors in Nicholas C. Wu University(University of Illinois at Urbana-Champaign)

Co-Authors

H-index: 65
Ren Sun

Ren Sun

University of California, Los Angeles

H-index: 19
Yushen Du

Yushen Du

University of California, Los Angeles

H-index: 14
Hangfei Qi

Hangfei Qi

University of California, Los Angeles

H-index: 8
Yiquan Wang

Yiquan Wang

University of Illinois at Urbana-Champaign

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