Nathaniel A. Hathaway

About Nathaniel A. Hathaway

Nathaniel A. Hathaway, With an exceptional h-index of 18 and a recent h-index of 18 (since 2020), a distinguished researcher at University of North Carolina at Chapel Hill, specializes in the field of Mechanisms of mammalian genome regulation, chemical biology and drug discovery.

His recent articles reflect a diverse array of research interests and contributions to the field:

First-in-class chemical induced proximity system achieves dose-dependent control of TP53 activation in gastric cancer

VHL1 activation with a CRISPR-based gene activation platform causes increased MLKL expression and triggers necroptosis in renal cell carcinoma

Chemical epigenetic regulation of adeno-associated virus delivered transgenes

Relationship between lysine methyltransferase levels and heterochromatin gene repression in living cells and in silico

Dynamics of heterochromatin formation at submolecular resolution

Characterization of Hepatoma-Derived Growth Factor-Related Protein 2 Interactions with Heterochromatin

Bioorthogonal chemical epigenetic modifiers enable dose-dependent CRISPR targeted gene activation in mammalian cells

A simulation model of heterochromatin formation at submolecular detail

Nathaniel A. Hathaway Information

University

Position

Associate Professor, the UNC Eshelman School of Pharmacy, Chemical Biology and Medicinal Chemistry

Citations(all)

3483

Citations(since 2020)

1287

Cited By

2709

hIndex(all)

18

hIndex(since 2020)

18

i10Index(all)

21

i10Index(since 2020)

21

Email

University Profile Page

Google Scholar

Nathaniel A. Hathaway Skills & Research Interests

Mechanisms of mammalian genome regulation

chemical biology and drug discovery

Top articles of Nathaniel A. Hathaway

Title

Journal

Author(s)

Publication Date

First-in-class chemical induced proximity system achieves dose-dependent control of TP53 activation in gastric cancer

Cancer Research

Ryan M Kemper

Travis J Nelson

Nathaniel A Hathaway

Daniel J Crona

2024/3/22

VHL1 activation with a CRISPR-based gene activation platform causes increased MLKL expression and triggers necroptosis in renal cell carcinoma

Cancer Research

Manfred S Meng

Ryan M Kemper

Travis J Nelson

Nathaniel A Hathaway

Daniel James Crona

2024/3/22

Chemical epigenetic regulation of adeno-associated virus delivered transgenes

Human Gene Therapy

Jessica D Umaña

Sara R Wasserman

Liujiang Song

Arushi A Goel

Xufen Yu

...

2023/9/1

Relationship between lysine methyltransferase levels and heterochromatin gene repression in living cells and in silico

PNAS nexus

Xiaokang Yan

Michael R Williams

Ameriks D Barboza Castillo

Dmitri Kireev

Nathaniel A Hathaway

2023/4/1

Dynamics of heterochromatin formation at submolecular resolution

Biophysical Journal

Michael R Williams

Yan Xiaokang

Nathaniel Hathaway

Dmitri Kireev

2023/2/10

Characterization of Hepatoma-Derived Growth Factor-Related Protein 2 Interactions with Heterochromatin

Cancer Research

Gnanasekar Munirathinam

Aditya Shetty

Abhilash Samykutty

Gajalakshmi Dakshinamoorthy

Guoxing Zheng

...

2011/4/15

Bioorthogonal chemical epigenetic modifiers enable dose-dependent CRISPR targeted gene activation in mammalian cells

ACS Synthetic Biology

Dongbo Lu

Caroline A Foley

Shama V Birla

Austin J Hepperla

Jeremy M Simon

...

2022/3/18

A simulation model of heterochromatin formation at submolecular detail

Iscience

Michael R Williams

Yan Xiaokang

Nathaniel A Hathaway

Dmitri Kireev

2022/7/15

A peptidomimetic ligand targeting the chromodomain of MPP8 reveals HRP2’s association with the HUSH complex

ACS chemical biology

Jarod M Waybright

Sarah E Clinkscales

Kimberly D Barnash

Gabrielle R Budziszewski

Justin M Rectenwald

...

2021/8/20

Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks

Nucleic Acids Research

Wanjuan Feng

Dennis A Simpson

Jang-Eun Cho

Juan Carvajal-Garcia

Chelsea M Smith

...

2021/5/21

Epigenetic control of a local chromatin landscape

Anna M Chiarella

Dongbo Lu

Nathaniel A Hathaway

2020/1/31

Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery

Nature biotechnology

Anna M Chiarella

Kyle V Butler

Berkley E Gryder

Dongbo Lu

Tiffany A Wang

...

2020/1

LSH mediates gene repression through macroH2A deposition

Nature Communications

Kai Ni

Jianke Ren

Xiaoping Xu

Yafeng He

Richard Finney

...

2020/11/6

Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding

Nucleic acids research

Aleksandra Skrajna

Dennis Goldfarb

Katarzyna M Kedziora

Emily M Cousins

Gavin D Grant

...

2020/9/25

See List of Professors in Nathaniel A. Hathaway University(University of North Carolina at Chapel Hill)