Mikael Widersten

Mikael Widersten

Uppsala Universitet

H-index: 36

Europe-Sweden

About Mikael Widersten

Mikael Widersten, With an exceptional h-index of 36 and a recent h-index of 14 (since 2020), a distinguished researcher at Uppsala Universitet, specializes in the field of Biochemistry, enzyme catalysis, protein evolution.

His recent articles reflect a diverse array of research interests and contributions to the field:

Structural enzymology studies with the substrate 3S‐hydroxybutanoyl‐CoA: bifunctional MFE1 is a less efficient dehydrogenase than monofunctional HAD

Engineered aldolases catalyzing stereoselective aldol reactions between aryl-substituted ketones and aldehydes

Structures of lactaldehyde reductase, FucO, link enzyme activity to hydrogen bond networks and conformational dynamics

Crystal structures and kinetic studies of a laboratory evolved aldehyde reductase explain the dramatic shift of its new substrate specificity

Facile synthesis of 2-hydroxyacetophenone from racemic styrene oxide catalyzed by engineered enzymes

Structure and mechanism of a cold-adapted bacterial lipase

The Role of Substrate-Coenzyme Crosstalk in Determining Turnover Rates in Rhodococcus ruber Alcohol Dehydrogenase

Engineering aldolases for asymmetric synthesis

Mikael Widersten Information

University

Position

Professor of Biochemistry

Citations(all)

5929

Citations(since 2020)

721

Cited By

5619

hIndex(all)

36

hIndex(since 2020)

14

i10Index(all)

70

i10Index(since 2020)

23

Email

University Profile Page

Uppsala Universitet

Google Scholar

View Google Scholar Profile

Mikael Widersten Skills & Research Interests

Biochemistry

enzyme catalysis

protein evolution

Top articles of Mikael Widersten

Title

Journal

Author(s)

Publication Date

Structural enzymology studies with the substrate 3S‐hydroxybutanoyl‐CoA: bifunctional MFE1 is a less efficient dehydrogenase than monofunctional HAD

FEBS Open Bio

Shruthi Sridhar

Tiila‐Riikka Kiema

Werner Schmitz

Mikael Widersten

Rik K Wierenga

2024/4

Engineered aldolases catalyzing stereoselective aldol reactions between aryl-substituted ketones and aldehydes

Catalysis Science & Technology

Eugenia Chukwu Cornelius

Michael Bartl

Louise J Persson

Ruisheng Xiong

Daniela Cederfelt

...

2023

Structures of lactaldehyde reductase, FucO, link enzyme activity to hydrogen bond networks and conformational dynamics

The FEBS journal

Alberto Zavarise

Shruthi Sridhar

Tiila‐Riikka Kiema

Rikkert K Wierenga

Mikael Widersten

2023/1

Crystal structures and kinetic studies of a laboratory evolved aldehyde reductase explain the dramatic shift of its new substrate specificity

IUCrJ

Shruthi Sridhar

Alberto Zavarise

T-R Kiema

Subhadra Dalwani

Tor Eriksson

...

2023/7/1

Facile synthesis of 2-hydroxyacetophenone from racemic styrene oxide catalyzed by engineered enzymes

Biotechnology letters

Isac Söderlund

Elias Tjärnhage

Emil Hamnevik

Mikael Widersten

2022/8

Structure and mechanism of a cold-adapted bacterial lipase

Biochemistry

Florian van der Ent

Bjarte A Lund

Linn Svalberg

Miha Purg

Ghislean Chukwu

...

2022/5/3

The Role of Substrate-Coenzyme Crosstalk in Determining Turnover Rates in Rhodococcus ruber Alcohol Dehydrogenase

ACS Catalysis

Thilak Reddy Enugala

Marina Corbella Morató

Shina CL Kamerlin

Mikael Widersten

2020/7/16

Engineering aldolases for asymmetric synthesis

Mikael Widersten

2020/1/1

See List of Professors in Mikael Widersten University(Uppsala Universitet)

Co-Authors

H-index: 52
Kamerlin SC*

Kamerlin SC*

Uppsala Universitet

H-index: 37
Per Berglund

Per Berglund

Kungliga Tekniska högskolan

H-index: 34
Fernanda Duarte

Fernanda Duarte

University of Oxford

H-index: 17
Michael C. Mossing

Michael C. Mossing

University of Mississippi

H-index: 15
Paul Bauer

Paul Bauer

Kungliga Tekniska högskolan

H-index: 12
Cecilia Blikstad

Cecilia Blikstad

University of California, Berkeley

academic-engine