Michele Cianci

About Michele Cianci

Michele Cianci, With an exceptional h-index of 32 and a recent h-index of 22 (since 2020), a distinguished researcher at Università Politecnica delle Marche, specializes in the field of Structural Enzymology, Transthyretin, Lipases, Lipid binding proteins, Crystallography and Cryo-EM.

His recent articles reflect a diverse array of research interests and contributions to the field:

Kinetic and structural details of urease inactivation by thiuram disulphides

Urease: structure, function, catalysis, and inhibition

3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity

Optimized ebselen-based inhibitors of bacterial ureases with nontypical mode of action

Understanding the mechanism of lipid–enzyme interactions in the limbus region of lipases at atomic resolution

Structural basis of human dimeric α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase inhibition with TES-1025

Molecular insights into the interaction between human nicotinamide phosphoribosyltransferase and Toll-like receptor 4

Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis

Michele Cianci Information

University

Position

Italy

Citations(all)

2870

Citations(since 2020)

1412

Cited By

2060

hIndex(all)

32

hIndex(since 2020)

22

i10Index(all)

51

i10Index(since 2020)

34

Email

University Profile Page

Università Politecnica delle Marche

Google Scholar

View Google Scholar Profile

Michele Cianci Skills & Research Interests

Structural Enzymology

Transthyretin

Lipases

Lipid binding proteins

Crystallography and Cryo-EM

Top articles of Michele Cianci

Title

Journal

Author(s)

Publication Date

Kinetic and structural details of urease inactivation by thiuram disulphides

Journal of Inorganic Biochemistry

Luca Mazzei

Arundhati Paul

Michele Cianci

Marta Devodier

Davide Mandelli

...

2024/1/1

Urease: structure, function, catalysis, and inhibition

Luca Mazzei

Francesco Musiani

Barbara Zambelli

Stefano Benini

Michele Cianci

...

2024

3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity

International Journal of Molecular Sciences

Thanalai Poonsiri

Davide Dell’Accantera

Valentina Loconte

Alessandro Casnati

Laura Cervoni

...

2023/12/29

Optimized ebselen-based inhibitors of bacterial ureases with nontypical mode of action

Journal of Medicinal Chemistry

Katarzyna Macegoniuk

Wojciech Tabor

Luca Mazzei

Michele Cianci

Mirosław Giurg

...

2023/1/20

Understanding the mechanism of lipid–enzyme interactions in the limbus region of lipases at atomic resolution

Acta Crystallographica Section A: Foundations and Advances

M Cianci

2022/8/23

Structural basis of human dimeric α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase inhibition with TES-1025

Frontiers in Molecular Biosciences

Michele Cianci

Nicola Giacchè

Lucia Cialabrini

Andrea Carotti

Paride Liscio

...

2022/4/7

Molecular insights into the interaction between human nicotinamide phosphoribosyltransferase and Toll-like receptor 4

Journal of Biological Chemistry

Massimiliano Gasparrini

Francesca Mazzola

Massimiliano Cuccioloni

Leonardo Sorci

Valentina Audrito

...

2022/3/1

Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis

Journal of Structural Biology

Gabriele Minazzato

Massimiliano Gasparrini

Annie Heroux

Natalia V Sernova

Dmitry A Rodionov

...

2022/12/1

Inhibition of Urease by Hydroquinones: A Structural and Kinetic Study

Chemistry–A European Journal

Luca Mazzei

Michele Cianci

Stefano Ciurli

2022/11/16

Principles of the mechanism of interfacial activation of a lipase: open and closed states and lipid–enzyme interactions in the limbus region of Candida antarctica Lipase B

Acta Crystallographica Section A: Foundations and Advances

M Cianci

2021/8/1

Kinetic and structural analysis of the inactivation of urease by mixed-ligand phosphine halide Ag (I) complexes

Journal of inorganic biochemistry

Luca Mazzei

Damiano Cirri

Michele Cianci

Luigi Messori

Stefano Ciurli

2021/5/1

Inhibition of Urease, a Ni‐Enzyme: The Reactivity of a Key Thiol With Mono‐and Di‐Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies

Angewandte Chemie

Luca Mazzei

Umberto Contaldo

Francesco Musiani

Michele Cianci

Greta Bagnolini

...

2021/3/8

Structure, dynamics, and function of SrnR, a transcription factor for nickel-dependent gene expression

Metallomics

Luca Mazzei

Francesco Musiani

Szymon Żerko

Wiktor Koźminski

Michele Cianci

...

2021/12

INTRODUCTION TO PROTEINS, Introduction to Proteins: Structure, Function, and Motion: Amit Kessel, Nir Ben-Tal, Abingdon, UK, CRC press, Taylor & Francis Group, 2020, 932 pp …

Michele Cianci

2021/1/2

Handbook of food enzymology: edited by John R. Whitaker, Alphons GJ Voragen, Dominic WS Wong, CRC Press, Taylor & Francis Group, 6000 Broken Sound Parkway, NW, Suite 300, Boca …

Michele Cianci

2021/10/2

Medicinal Au (I) compounds targeting urease as prospective antimicrobial agents: Unveiling the structural basis for enzyme inhibition

Dalton Transactions

Luca Mazzei

Lara Massai

Michele Cianci

Luigi Messori

Stefano Ciurli

2021

Interactions of tolcapone analogues as stabilizers of the amyloidogenic protein transthyretin

Bioorganic Chemistry

Valentina Loconte

Michele Cianci

Ilaria Menozzi

Davide Sbravati

Francesco Sansone

...

2020/10/1

Principles of lipid–enzyme interactions in the limbus region of the catalytic site of Candida antarctica Lipase B

International journal of biological macromolecules

Lucia Silvestrini

Michele Cianci

2020/9/1

Functional characterization of COG1713 (YqeK) as a novel diadenosine tetraphosphate hydrolase family

Journal of Bacteriology

Gabriele Minazzato

Massimiliano Gasparrini

Adolfo Amici

Michele Cianci

Francesca Mazzola

...

2020/4/27

Food Quality and Functionality

The First Outstanding 50 Years of “Università Politecnica delle Marche” Research Achievements in Life Sciences

Deborah Pacetti

Bruno Mezzetti

Francesca Balducci

Michele Balzano

Patricia Carloni

...

2020

See List of Professors in Michele Cianci University(Università Politecnica delle Marche)

Co-Authors

H-index: 99
Gerd Ulrich Nienhaus

Gerd Ulrich Nienhaus

Karlsruher Institut für Technologie

H-index: 78
Daniele Del Rio

Daniele Del Rio

Università degli Studi di Parma

H-index: 54
Stefano Ciurli

Stefano Ciurli

Università degli Studi di Bologna

H-index: 53
John R Helliwell

John R Helliwell

Manchester University

H-index: 37
beatrice vallone

beatrice vallone

Sapienza Università di Roma

H-index: 34
Francesco Musiani

Francesco Musiani

Università degli Studi di Bologna

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