Michael McDonough
University of Oxford
H-index: 55
Europe-United Kingdom
Top articles of Michael McDonough
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Cardiac stress leads to regulation of Filamin C dimerisation via an ancient phosphorylation-modulated interaction with HSPB7 | bioRxiv | Zihao Wang Guodong Cao Miranda P Collier Xingyu Qiu Sophie Broadway-Stringer | 2024 |
Small Molecule Ligands of the BET-like Bromodomain, SmBRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development | Journal of Medicinal Chemistry | Matthias Schiedel Darius JB McArdle Gilda Padalino Anthony KN Chan Josephine Forde-Thomas | 2023/12/4 |
Structural basis for binding of the renal carcinoma target hypoxia‐inducible factor 2α to prolyl hydroxylase domain 2 | Proteins: Structure, Function, and Bioinformatics | William D Figg Jr Giorgia Fiorini Rasheduzzaman Chowdhury Yu Nakashima Anthony Tumber | 2023/11 |
Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation | ACS Chemical Biology | Adam M Thomas Marta Serafini Emma K Grant Edward AJ Coombs Joseph P Bluck | 2023/10/24 |
In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease | Nature Chemistry | Takashi Miura Tika R Malla C David Owen Anthony Tumber Lennart Brewitz | 2023/7 |
Inhibitors of metallo-beta-lactamases | 2021/5/13 | ||
Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors | Nature Chemistry | Jürgen Brem Tharindi Panduwawala Jon Ulf Hansen Joanne Hewitt Edgars Liepins | 2022/1 |
An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides | Nature communications | Ysobel R Baker Cameron Thorpe Jinfeng Chen Laura M Poller Lina Cox | 2022/7/12 |
Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5–RNA complexes | Nucleic Acids Research | Simranjeet Kaur Nok Yin Tam Michael A McDonough Christopher J Schofield Wei Shen Aik | 2022/4/22 |
Studies on the Reactions of Biapenem with VIM Metallo β-Lactamases and the Serine β-Lactamase KPC-2 | Antibiotics | Anka Lucic Tika R Malla Karina Calvopiña Catherine L Tooke Jürgen Brem | 2022/3/16 |
Inhibition of JMJD6 by 2‐Oxoglutarate Mimics | ChemMedChem | Md Sailful Islam Cyrille C Thinnes James P Holt‐Martyn Rasheduzzaman Chowdhury Michael A McDonough | 2022/1/5 |
In situ inhibitor synthesis and screening by fluorescence polarization: An efficient approach for accelerating drug discovery | Angewandte Chemie | Zhihong Li Yue Wu Shuai Zhen Kaijun Su Linjian Zhang | 2022/11/7 |
Human Oxygenase Variants Employing a Single Protein FeII Ligand Are Catalytically Active | Angewandte Chemie | Amelia Brasnett Inga Pfeffer Lennart Brewitz Rasheduzzaman Chowdhury Yu Nakashima | 2021/6/21 |
Inhibition of the oxygen-sensing asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor: a potential hypoxia response modulating strategy | Yue Wu Zhihong Li Michael A McDonough Christopher J Schofield Xiaojin Zhang | 2021/5/24 | |
Structure-based design of selective fat mass and obesity associated protein (FTO) inhibitors | Journal of Medicinal Chemistry | Shifali Shishodia Marina Demetriades Dong Zhang Nok Yin Tam Pratheesh Maheswaran | 2021/11/11 |
Faropenem reacts with serine and metallo-β-lactamases to give multiple products | European journal of medicinal chemistry | Anka Lucic Philip Hinchliffe Tika R Malla Catherine L Tooke Jürgen Brem | 2021/4/5 |
X-ray free-electron laser studies reveal correlated motion during isopenicillin N synthase catalysis | Science Advances | Patrick Rabe Jos JAG Kamps Kyle D Sutherlin James DS Linyard Pierre Aller | 2021/8/20 |
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes | Nature communications | Erna Davydova Tadahiro Shimazu Maren Kirstin Schuhmacher Magnus E Jakobsson Hanneke LDM Willemen | 2021/2/9 |
HIF-prolyl-hydroxylase 2 clinical inhibitor complex structure and XChem fragment-based screen obtained with succinate co-product used as a crystallisation tool | Acta Crystallographica Section A: Foundations and Advances | William D Figg Jr Michael A McDonough Yu Nakashima Rasheduzzaman Chowdhury Christopher J Schofield | 2021/8/14 |
Structural basis of prolyl hydroxylase domain inhibition by molidustat | ChemMedChem | William D Figg Jr Michael A McDonough Rasheduzzaman Chowdhury Yu Nakashima Zhihong Zhang | 2021/7/6 |
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