Michael Laub

Michael Laub

Massachusetts Institute of Technology

H-index: 63

North America-United States

About Michael Laub

Michael Laub, With an exceptional h-index of 63 and a recent h-index of 46 (since 2020), a distinguished researcher at Massachusetts Institute of Technology,

His recent articles reflect a diverse array of research interests and contributions to the field:

Anti-viral defense by an ADP-ribosyltransferase that targets mRNA to block translation

Mechanism of phage sensing and abortion by toxin-antitoxin-chaperone systems

Protein design using structure-based residue preferences

A phage-encoded RNA-binding protein inhibits the antiviral activity of a toxin–antitoxin system

Selection of a de novo gene that can promote survival of Escherichiacoli by modulating protein homeostasis pathways

Toxic antiphage defense proteins inhibited by intragenic antitoxin proteins

Marginal specificity in protein interactions constrains evolution of a paralogous family

Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles

Michael Laub Information

University

Position

Professor of Biology and Howard Hughes Medical Institute

Citations(all)

18304

Citations(since 2020)

6725

Cited By

9717

hIndex(all)

63

hIndex(since 2020)

46

i10Index(all)

101

i10Index(since 2020)

94

Email

University Profile Page

Massachusetts Institute of Technology

Google Scholar

View Google Scholar Profile

Top articles of Michael Laub

Title

Journal

Author(s)

Publication Date

Anti-viral defense by an ADP-ribosyltransferase that targets mRNA to block translation

bioRxiv

Christopher N Vassallo

Christopher R Doering

Michael T Laub

2024

Mechanism of phage sensing and abortion by toxin-antitoxin-chaperone systems

bioRxiv

Toomas Mets

Tatsuaki Kurata

Karin Ernits

Marcus JO Johansson

Sophie Z Craig

...

2024

Protein design using structure-based residue preferences

Nature Communications

David Ding

Ada Y Shaw

Sam Sinai

Nathan Rollins

Noam Prywes

...

2024/2/22

A phage-encoded RNA-binding protein inhibits the antiviral activity of a toxin–antitoxin system

Nucleic Acids Research

Chantal K Guegler

Gabriella IC Teodoro

Sriram Srikant

Keerthana Chetlapalli

Christopher R Doering

...

2024/2/9

Selection of a de novo gene that can promote survival of Escherichiacoli by modulating protein homeostasis pathways

Nature Ecology & Evolution

Idan Frumkin

Michael T Laub

2023/12

Toxic antiphage defense proteins inhibited by intragenic antitoxin proteins

Proceedings of the National Academy of Sciences

Aoshu Zhong

Xiaofang Jiang

Alison B Hickman

Katherine Klier

Gabriella IC Teodoro

...

2023/8/1

Marginal specificity in protein interactions constrains evolution of a paralogous family

Proceedings of the National Academy of Sciences

Dia A Ghose

Kaitlyn E Przydzial

Emily M Mahoney

Amy E Keating

Michael T Laub

2023/5/2

Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles

Nature communications

Ross D Jones

Yili Qian

Katherine Ilia

Benjamin Wang

Michael T Laub

...

2022/3/31

A silent operon of Photorhabdus luminescens encodes a prodrug mimic of GTP

MBio

Negar Shahsavari

Boyuan Wang

Yu Imai

Miho Mori

Sangkeun Son

...

2022/6/28

Prophage-like gene transfer agents promote Caulobacter crescentus survival and DNA repair during stationary phase

PLoS biology

Kevin Gozzi

Ngat T Tran

Joshua W Modell

Tung BK Le

Michael T Laub

2022/11/3

Ancestral reconstruction of duplicated signaling proteins reveals the evolution of signaling specificity

Elife

Isabel Nocedal

Michael T Laub

2022/6/10

A functional selection reveals previously undetected anti-phage defence systems in the E. coli pangenome

Nature microbiology

Christopher N Vassallo

Christopher R Doering

Megan L Littlehale

Gabriella IC Teodoro

Michael T Laub

2022/10

ssDNA is an allosteric regulator of the C. crescentus SOS-independent DNA damage response transcription activator, DriD

Genes & Development

Kevin Gozzi

Raul Salinas

Viet D Nguyen

Michael T Laub

Maria A Schumacher

2022/5/1

Toxin-antitoxin systems as phage defense elements

Michele LeRoux

Michael T Laub

2022/9/8

Co-evolution of interacting proteins through non-contacting and non-specific mutations

Nature ecology & evolution

David Ding

Anna G Green

Boyuan Wang

Thuy-Lan Vo Lite

Eli N Weinstein

...

2022/5

The evolution of a counter-defense mechanism in a virus constrains its host range

Elife

Sriram Srikant

Chantal K Guegler

Michael T Laub

2022/8/4

Escherichia coli SymE is a DNA‐binding protein that can condense the nucleoid

Molecular microbiology

Mary K Thompson

Isabel Nocedal

Peter H Culviner

Tong Zhang

Kevin R Gozzi

...

2022/4

The DarTG toxin-antitoxin system provides phage defence by ADP-ribosylating viral DNA

Nature microbiology

Michele LeRoux

Sriram Srikant

Gabriella IC Teodoro

Tong Zhang

Megan L Littlehale

...

2022/7

Direct activation of a bacterial innate immune system by a viral capsid protein

Nature

Tong Zhang

Hedvig Tamman

Kyo Coppieters’t Wallant

Tatsuaki Kurata

Michele LeRoux

...

2022/12/1

Shutoff of host transcription triggers a toxin-antitoxin system to cleave phage RNA and abort infection

Molecular Cell

Chantal K Guegler

Michael T Laub

2021/6/3

See List of Professors in Michael Laub University(Massachusetts Institute of Technology)

Co-Authors

H-index: 96
Job Dekker

Job Dekker

University of Massachusetts Medical School

H-index: 80
Leonid Mirny

Leonid Mirny

Massachusetts Institute of Technology

H-index: 74
Christopher Voigt

Christopher Voigt

Massachusetts Institute of Technology

H-index: 61
Kerwyn Casey Huang

Kerwyn Casey Huang

Stanford University

H-index: 49
Bryan R. Lajoie

Bryan R. Lajoie

University of Massachusetts Medical School

H-index: 31
Maxim (Max) Imakaev

Maxim (Max) Imakaev

Massachusetts Institute of Technology

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