Max Jan
Harvard University
H-index: 19
North America-United States
Top articles of Max Jan
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Genetic retargeting of E3 ligases to enhance CAR T cell therapy | Cell Chemical Biology | Isabel C Lane Gabriele Kembuan Jeannie Carreiro Michael C Kann William Lin | 2024/2/15 |
Targeting solid tumor antigens with chimeric receptors: cancer biology meets synthetic immunology | Gabriele J Kembuan Joanna Y Kim Marcela V Maus Max Jan | 2024/2/13 | |
Proteolysis-targeting chimeras with reduced off-targets | Nature Chemistry | Tuan M Nguyen Vedagopuram Sreekanth Arghya Deb Praveen Kokkonda Praveen K Tiwari | 2024/2 |
Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma | Clinical Cancer Research | Marc Wehrli Samantha Guinn Filippo Birocchi Adam Kuo Yi Sun | 2024/4/2 |
Developing a lenalidomide-inducible safety switch for CAR T cell therapy | Cancer Research | Ditsa Sarkar William Lin Joanna Y Kim Nelson H Knudsen Isabel C Lane | 2024/3/22 |
Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7 | Leukemia | Michael C Kann Emily M Schneider Antonio J Almazan Isabel C Lane Amanda A Bouffard | 2024/3 |
Zinc finger degradation domains | 2023/5/18 | ||
A molecular glue approach to control the half-life of CRISPR-based technologies | bioRxiv | Vedagopuram Sreekanth Max Jan Kevin T Zhao Donghyun Lim Jessie R Davis | 2023/3/20 |
A Lenalidomide-Inducible Suicide Switch for Gene-and Cell-Based Therapy | Blood | William Lin Ditsa Sarkar Joanna Y Kim Nelson H Knudsen Isabel C Lane | 2023/11/28 |
Clonal hematopoiesis is associated with protection from Alzheimer’s disease | Nature Medicine | Hind Bouzid Julia A Belk Max Jan Yanyan Qi Chloé Sarnowski | 2023/7 |
CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours | Nature | Rebecca C Larson Michael C Kann Stefanie R Bailey Nicholas J Haradhvala Paula Montero Llopis | 2022/4/21 |
Lenalidomide switch control of CAR T-cell phenotype and function via degradable membrane-bound IL-7 | Cancer Research | Michael C Kann Alexander Tepper Harrison J Silva Isabel C Lane Amanda A Bouffard | 2022/6/15 |
Peptide tags for ligand induced degradation of fusion proteins | 2022/3/31 | ||
Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine | Science translational medicine | Mathieu Gigoux Morten O Holmström Roberta Zappasodi Joseph J Park Stephane Pourpe | 2022/6/15 |
Repurposing the damage repair protein methyl guanine methyl transferase as a ligand inducible fusion degron | ACS Chemical Biology | Gosia M Murawska Caspar Vogel Max Jan Xinyan Lu Matthias Schild | 2022/1/4 |
Mesothelin CAR T cells secreting FAP specific T cell engaging molecule (TEAM) target pancreatic cancer and its tumor microenvironment (TME) | Cancer Research | Marc Wehrli Adam Kuo Rebecca Larson Irene Scarfò Amanda Bouffard | 2022/6/15 |
Patients with Deleterious Germline Variants in STXBP2 Develop Toxicity after CAR-T Cell Therapy with Axicabtagene Ciloleucel | Blood | Mark B Leick Seunghun Han Kathleen ME Gallagher Harrison Silva Grace Martin | 2022/11/15 |
Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia | Cancer cell | Mark B Leick Harrison Silva Irene Scarfò Rebecca Larson Bryan D Choi | 2022/5/9 |
SEAKER cells coordinate cellular immunotherapy with localized chemotherapy | Isabel C Lane Max Jan | 2022/10/1 | |
Loss of IFNgR1 signaling glioblastoma drives resistance to CAR T cell binding avidity and cytotoxicity due to lower downstream expression of ICAM-1 | The Journal of Immunology | Rebecca Larson Michael Kann Stefanie Bailey Nicholas Haradhvala Kai Stewart | 2022/5/1 |
