Matthieu Schapira

Matthieu Schapira

University of Toronto

H-index: 54

North America-Canada

About Matthieu Schapira

Matthieu Schapira, With an exceptional h-index of 54 and a recent h-index of 37 (since 2020), a distinguished researcher at University of Toronto, specializes in the field of Epigenetics, Ubiquitin biology, Structural Bioinformatics, Computer Assisted Drug Design.

His recent articles reflect a diverse array of research interests and contributions to the field:

A resource to enable chemical biology and drug discovery of WDR Proteins

Emerging structure-based computational methods to screen the exploding accessible chemical space

Big data and benchmarking initiatives to bridge the gap from AlphaFold to drug design

Chemical Coverage of the Human Reactome

A chemical probe to modulate human GID4 Pro/N-degron interactions

Methods for computer-assisted PROTAC design.

Benchmarking PROTAC docking and virtual screening tools

Discovery of a novel DCAF1 ligand using a drug–target interaction prediction model: generalizing machine learning to new drug targets

Matthieu Schapira Information

University

Position

Associate Professor

Citations(all)

16075

Citations(since 2020)

7260

Cited By

11345

hIndex(all)

54

hIndex(since 2020)

37

i10Index(all)

114

i10Index(since 2020)

86

Email

University Profile Page

University of Toronto

Google Scholar

View Google Scholar Profile

Matthieu Schapira Skills & Research Interests

Epigenetics

Ubiquitin biology

Structural Bioinformatics

Computer Assisted Drug Design

Top articles of Matthieu Schapira

Title

Journal

Author(s)

Publication Date

A resource to enable chemical biology and drug discovery of WDR Proteins

bioRxiv

Cheryl H Arrowsmith

Suzanne Ackloo

Fengling Li

Magda Szewczyk

Almagul Seitova

...

2024

Emerging structure-based computational methods to screen the exploding accessible chemical space

Corentin Bedart

Conrad Veranso Simoben

Matthieu Schapira

2024/6/1

Big data and benchmarking initiatives to bridge the gap from AlphaFold to drug design

Nature Chemical Biology

Matthieu Schapira

Levon Halabelian

Cheryl H Arrowsmith

Rachel J Harding

2024/3/8

Chemical Coverage of the Human Reactome

bioRxiv

Haejin Angela Kwak

Lihua Liu

Claudia Tredup

Sandra Röhm

Panagiotis Prinos

...

2024

A chemical probe to modulate human GID4 Pro/N-degron interactions

bioRxiv

Dominic DG Owens

Matthew ER Maitland

Aliakbar Khalili Yazdi

Xiaosheng Song

Martin P Schwalm

...

2023/1/18

Methods for computer-assisted PROTAC design.

Evianne Rovers

Matthieu Schapira

2023/7/21

Benchmarking PROTAC docking and virtual screening tools

bioRxiv

Evianne Rovers

Matthieu Schapira

2023

Discovery of a novel DCAF1 ligand using a drug–target interaction prediction model: generalizing machine learning to new drug targets

Journal of Chemical Information and Modeling

Serah W Kimani

Julie Owen

Stuart R Green

Fengling Li

Yanjun Li

...

2023/6/23

Small Molecule Screen Identifies Non-Catalytic USP3 Chemical Handle

ACS omega

Mandeep K Mann

Esther Wolf

Madhushika Silva

Haejin Angela Kwak

Brian Wilson

...

2023/12/15

Target 2035–an update on private sector contributions

RSC Medicinal Chemistry

Suzanne Ackloo

Albert A Antolin

Jose Manuel Bartolome

Hartmut Beck

Alex Bullock

...

2023

Illuminating the druggable genome through patent bioactivity data

PeerJ

Maria P Magariños

Anna Gaulton

Eloy Félix

Tevfik Kiziloren

Ricardo Arcila

...

2023/5/2

A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening

Corentin Bedart

Grace Shimokura

Frederick G West

Tabitha E Wood

Robert A Batey

...

2023/12/8

RAS and PP2A activities converge on epigenetic gene regulation

Life science alliance

Anna Aakula

Mukund Sharma

Francesco Tabaro

Reetta Nätkin

Jesse Kamila

...

2023/5/1

Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors

bioRxiv

AkshatKumar Nigam

Matthew FD Hurley

Fengling Li

Eva Konkoǐová

Martin Klíma

...

2023/10/4

RAS and PP2A activities converge on phosphoregulation of epigenetic complexes in cancer

Cancer Research

Mukund Sharma

Anna Aakula

Francesco Tabaro

Henrik Honkanen

Jesse Kamila

...

2023/4/4

Discovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6

Journal of Medicinal Chemistry

Rachel J Harding

Ivan Franzoni

Mandeep K Mann

Magdalena M Szewczyk

Bijan Mirabi

...

2023/7/27

Structure-Based Survey of the Human Proteome for Opportunities in Proximity Pharmacology

bioRxiv

Evianne Rovers

Matthieu Schapira

2022/1/15

A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization

Nature chemical biology

David Dilworth

Ronan P Hanley

Renato Ferreira de Freitas

Abdellah Allali-Hassani

Mengqi Zhou

...

2022/1

Discovery of small molecule antagonists of human Retinoblastoma Binding Protein 4 (RBBP4)

bioRxiv

Sumera Perveen

Carlos A Zepeda-Velázquez

David McLeod

Richard Marcellus

Mohammed Mohammed

...

2022/1/5

ProxyBind: A compendium of binding sites for proximity-induced pharmacology

Computational and Structural Biotechnology Journal

Evianne Rovers

Lihua Liu

Matthieu Schapira

2022/1/1

See List of Professors in Matthieu Schapira University(University of Toronto)