Matthew J. Merrins, PhD

Matthew J. Merrins, PhD

University of Wisconsin-Madison

H-index: 28

North America-United States

About Matthew J. Merrins, PhD

Matthew J. Merrins, PhD, With an exceptional h-index of 28 and a recent h-index of 23 (since 2020), a distinguished researcher at University of Wisconsin-Madison, specializes in the field of Islet Biology, Metabolism, Type 2 Diabetes.

His recent articles reflect a diverse array of research interests and contributions to the field:

Glucose Regulation of β-Cell KATP Channels: It Is Time for a New Model!

LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells

1747-P: Islet Ca2+ Dynamics, Heterogeneity, and Consistency in Three Dimensions with Activators of Pyruvate Kinase

Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells

EP3 signaling is decoupled from the regulation of glucose-stimulated insulin secretion in β-cells compensating for obesity and insulin resistance

A plasma membrane-associated glycolytic metabolon is functionally coupled to KATP channels in pancreatic α and β cells from humans and mice

Novel regulators of islet function identified from genetic variation in mouse islet Ca2+ oscillations

Leucine suppresses glucagon secretion from pancreatic islets by directly modulating α-cell cAMP

Matthew J. Merrins, PhD Information

University

Position

Assistant Professor

Citations(all)

2412

Citations(since 2020)

1823

Cited By

1276

hIndex(all)

28

hIndex(since 2020)

23

i10Index(all)

36

i10Index(since 2020)

34

Email

University Profile Page

University of Wisconsin-Madison

Google Scholar

View Google Scholar Profile

Matthew J. Merrins, PhD Skills & Research Interests

Islet Biology

Metabolism

Type 2 Diabetes

Top articles of Matthew J. Merrins, PhD

Title

Journal

Author(s)

Publication Date

Glucose Regulation of β-Cell KATP Channels: It Is Time for a New Model!

Diabetes

Matthew J Merrins

Richard G Kibbey

2024/4/19

LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells

Cell Reports

Federica Cuozzo

Katrina Viloria

Ali H Shilleh

Daniela Nasteska

Charlotte Frazer-Morris

...

2024/4/23

1747-P: Islet Ca2+ Dynamics, Heterogeneity, and Consistency in Three Dimensions with Activators of Pyruvate Kinase

Diabetes

JENNIFER BRIGGS

ERLI JIN

MATTHEW J MERRINS

RICHARD K BENNINGER

2023/6/20

Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells

Cell reports

Weiwei Xu

MM Fahd Qadir

Daniela Nasteska

Paula Mota de Sa

Caroline M Gorvin

...

2023/5/30

EP3 signaling is decoupled from the regulation of glucose-stimulated insulin secretion in β-cells compensating for obesity and insulin resistance

Islets

Michael D Schaid

Jeffrey M Harrington

Grant M Kelly

Sophia M Sdao

Matthew J Merrins

...

2023/12/31

A plasma membrane-associated glycolytic metabolon is functionally coupled to KATP channels in pancreatic α and β cells from humans and mice

CELL REPORTS

Thuong Ho

Evgeniy Potapenko

Dawn B Davis

Matthew J Merrins

2023/4/25

Novel regulators of islet function identified from genetic variation in mouse islet Ca2+ oscillations

Elife

Christopher H Emfinger

Lauren E Clark

Brian Yandell

Kathryn L Schueler

Shane P Simonett

...

2023/10/3

Leucine suppresses glucagon secretion from pancreatic islets by directly modulating α-cell cAMP

bioRxiv

Emily R Knuth

Hannah R Foster

Erli Jin

Matthew J Merrins

2023/7/31

What the BTBR/J mouse has taught us about diabetes and diabetic complications

Mark P Keller

Kelly L Hudkins

Anath Shalev

Sushant Bhatnagar

Melkam A Kebede

...

2023/7/7

A glycolytic enzyme complex and creatine kinase locally and differentially regulate ATP-sensitive potassium (KATP) channels in pancreatic islet alpha and beta cells

Biophysical Journal

Thuong Ho

Evgeniy Potapenko

Matthew J Merrins

2022/2/11

Metabolic cycles and signals for insulin secretion

Matthew J Merrins

Barbara E Corkey

Richard G Kibbey

Marc Prentki

2022/7/5

316-OR: Genetic Deletion of Beta-Cell Pkm1, Pkm2, and Pck2 Identifies PEP as an Essential Signal for Compartmentalized KATP Closure and Cycling of the Insulin Secretory Pathway

Diabetes

Hannah R Foster

Thuong Ho

Evgeniy Potapenko

Rebecca L Cardone

Richard Kibbey

...

2022/6/1

Anaplerotic amino acids attenuate glucagon secretion by lowering cAMP

Biophysical Journal

Emily R Knuth

Erli Jin

Hannah Foster

Matthew J Merrins

2022/2/11

β Cell–specific deletion of Zfp148 improves nutrient-stimulated β cell Ca2+ responses

JCI insight

Christopher H Emfinger

Eleonora de Klerk

Kathryn L Schueler

Mary E Rabaglia

Donnie S Stapleton

...

2022/5/5

The isoforms of pyruvate kinase act as nutrient sensors for the β-cell KATP channel

bioRxiv

Hannah R Foster

Thuong Ho

Evgeniy Potapenko

Sophia M Sdao

Sophie L Lewandowski

...

2022/2/10

Genetic deletion of mitochondrial PEP carboxykinase (PCK2) in pancreatic α cells increases amino acid-stimulated Ca2+ influx and boosts the excitability of neighboring β-cells

Biophysical Journal

Erli Jin

Emily Knuth

Matthew J Merrins

2022/2/11

Genetic variation in mouse islet Ca2+ oscillations reveals novel regulators of islet function

bioRxiv

Christopher H Emfinger

Lauren E Clark

Kathryn L Schueler

Shane P Simonett

Donnie S Stapleton

...

2022/1/1

High-resolution glucose tracing and in situ imaging reveals regulated lactate production in human pancreatic β cells

bioRxiv

Federica Cuozzo

Katrina Viloria

Ali H Shilleh

Daniela Nasteska

Charlotte Frazer-Morris

...

2022/12/21

Pyruvate kinase and GLP-1 receptor signaling converge on cAMP production to enhance insulin secretion

Biophysical Journal

Sophie L Lewandowski

Hannah R Foster

Megan E Capozzi

Jonathan E Campbell

Matthew J Merrins

2022/2/11

β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveals their essential role as nutrient sensors for the KATP channel

Elife

Hannah R Foster

Thuong Ho

Evgeniy Potapenko

Sophia M Sdao

Shih Ming Huang

...

2022/8/23

See List of Professors in Matthew J. Merrins, PhD University(University of Wisconsin-Madison)