Marta Filizola
Icahn School of Medicine at Mount Sinai
H-index: 49
North America-United States
Top articles of Marta Filizola
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation | bioRxiv | Richard Quintana-Feliciano Jithesh Kottur Mi Ni Rikhi Ghosh Leslie Salas-Estrada | 2024 |
Allosteric communication across the μ-opioid receptor-Gi1 protein complex induced by ligands of varying efficacy | Biophysical Journal | Bianca Fiorillo Rikhia Ghosh Kirill Konovalov Davide Provasi Marta Filizola | 2024/2/8 |
Structural basis for partial agonism and allosteric modulation of the 5HT3AR | Biophysical Journal | Kevin C Felt Madeleine Stauffer Leslie Salas-Estrada Marta Filizola Sudha Chakrapani | 2024/2/8 |
Leveraging protein language models and graph convolutional neural networks for accurate prediction of ligand bioactivity in class AG protein-coupled receptors | Biophysical Journal | Davide Provasi Nicholas Riina Olivia Cullen Marta Filizola | 2024/2/8 |
Transfer learning of deep hybrid ligand-based and structure-based drug discovery schemes for improved prediction of opioid ligands’ bioactivity | Biophysical Journal | Davide Provasi Marta Filizola | 2024/2/8 |
Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT1eR and 5-HT1FR | Science Advances | Gregory Zilberg Alexandra K Parpounas Audrey L Warren Bianca Fiorillo Davide Provasi | 2024/4/17 |
Structural basis of allosteric modulation of metabotropic glutamate receptor activation and desensitization | Biophysical Journal | Alexa Strauss Alberto J Gonzalez-Hernandez Joon Lee Nohely Abreu Purushotham Selvakumar | 2024/2/8 |
Structural basis for partial agonism in 5-HT3A receptors (jan, 10.1038/s41594-023-01140-2, 2024) | Nature Structural & Molecular Biology | Kevin Felt Madeleine Stauffer Leslie Salas-Estrada Peter R Guzzo Dejian Xie | 2024/1/4 |
Structural basis for ligand modulation and partial agonism of the 5-HT3R | Biophysical Journal | Kevin C Felt Letty Leslie Ann A Salas Estrada Madeleine Stauffer Peter R Guzzo Dejian Xie | 2023/2/10 |
Deciphering downstream receptor signaling | Science | Marta Filizola Jonathan A Javitch | 2023/12/22 |
AI-assisted de novo design of selective κ-opioid receptor antagonists for the treatment of opioid addiction | Biophysical Journal | Letty Leslie Ann Salas Estrada Davide Provasi Joao Marcelo Lamim Ribeiro Bianca Fiorillo Marta Filizola | 2023/2/10 |
Enhancing Opioid Bioactivity Predictions through Integration of Ligand-Based and Structure-Based Drug Discovery Strategies with Transfer and Deep Learning Techniques | The Journal of Physical Chemistry B | Davide Provasi Marta Filizola | 2023/12/12 |
Computational characterization of the binding mode and mechanism of action of tricyclic small molecules at 5-HT1E and 5-HT1F receptors | Proteins: Structure, Function, and Bioinformatics | Jerome De Ruyck Guillaume Brysbaert Vincent Villeret Marc Aumercier Marc F Lensink | 2018/10 |
De Novo Design of κ-Opioid Receptor Antagonists Using a Generative Deep-Learning Framework | Journal of Chemical Information and Modeling | Leslie Salas-Estrada Davide Provasi Xing Qiu Husnu Ümit Kaniskan Xi-Ping Huang | 2023/8/9 |
Sox11 inhibitors for treating mantle cell lymphoma | 2023/8/3 | ||
Gαs slow conformational transition upon GTP binding and a novel Gαs regulator | Iscience | Donghoon Ahn Davide Provasi Nguyen Minh Duc Jun Xu Leslie Salas-Estrada | 2023/5/19 |
Structure-Based Discovery of a Novel Class of Small-Molecule Pure Antagonists of Integrin αVβ3 | J. Chem. Inf. Model. | and Marta Filizola Soumyo Sen Aleksandar Spasic Anjana Sinha Jialing Wang Martin Bush | 2022/10/24 |
Long-lived conformational changes in active Gsα revealed in atomistic detail by integrating HDX-MS with enhanced molecular dynamics simulations | Biophysical Journal | Davide Provasi Aleksandar Spasic Nguyen Minh Duc Yang Du Donghoon Ahn | 2022/2/11 |
Metadynamics simulations leveraged by statistical analyses and artificial intelligence-based tools to inform the discovery of G protein-coupled receptor ligands | Leslie Salas-Estrada Bianca Fiorillo Marta Filizola | 2022/12/23 | |
Implementation of an online reporting system to identify unprofessional behaviors and mistreatment directed at trainees at an academic medical center | JAMA Network Open | I Michael Leitman David Muller Sophie Miller Basil G Hanss Thomas F Catron | 2022/12/1 |
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