Marko Hyvönen

Marko Hyvönen

University of Cambridge

H-index: 37

Europe-United Kingdom

About Marko Hyvönen

Marko Hyvönen, With an exceptional h-index of 37 and a recent h-index of 28 (since 2020), a distinguished researcher at University of Cambridge, specializes in the field of TGF-beta signalling, structure-guided drug discovery, fragment-based drug discovery, protein engineering.

His recent articles reflect a diverse array of research interests and contributions to the field:

CK2 Inhibitors Targeting Inside and Outside the Catalytic Box

O148: Unlocking Enhanced Immunity in Pancreatic Ductal Adenocarcinoma: Activins Interplay with CAF-Stroma Mechanisms

Benzo [c][2, 6] naphthyridine derivatives, compositions and therapeutic uses thereof

A versatile Halo-and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding

Selective Aurora A-TPX2 interaction inhibitors have in vivo efficacy as targeted anti-mitotic agents

SARS-CoV-2 Spike protein peptides displayed in the Pyrococcus furiosus RAD system preserve epitopes antigenicity, immunogenicity, and virus-neutralizing …

Cover Feature: Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase (ChemBioChem 1/2023)

Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agents

Marko Hyvönen Information

University

Position

___

Citations(all)

6005

Citations(since 2020)

2284

Cited By

4606

hIndex(all)

37

hIndex(since 2020)

28

i10Index(all)

68

i10Index(since 2020)

62

Email

University Profile Page

University of Cambridge

Google Scholar

View Google Scholar Profile

Marko Hyvönen Skills & Research Interests

TGF-beta signalling

structure-guided drug discovery

fragment-based drug discovery

protein engineering

Top articles of Marko Hyvönen

Title

Journal

Author(s)

Publication Date

CK2 Inhibitors Targeting Inside and Outside the Catalytic Box

Sophie Day-Riley

Rebekah M West

Paul D Brear

Marko Hyvönen

David R Spring

2024/3/26

O148: Unlocking Enhanced Immunity in Pancreatic Ductal Adenocarcinoma: Activins Interplay with CAF-Stroma Mechanisms

British Journal of Surgery

Simon McCluney

Danielle Park

Daniel Miller

Robert Bloxham

Merima Mehic

...

2024/3

Benzo [c][2, 6] naphthyridine derivatives, compositions and therapeutic uses thereof

2024/1/9

A versatile Halo-and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding

Communications Biology

Jerome Jatzlau

Wiktor Burdzinski

Michael Trumpp

Leon Obendorf

Kilian Roßmann

...

2023/1/12

Selective Aurora A-TPX2 interaction inhibitors have in vivo efficacy as targeted anti-mitotic agents

Simon R Stockwell

Duncan E Scott

Gerhard Fischer

Estrella Guarino

Timothy PC

2023/3/22

SARS-CoV-2 Spike protein peptides displayed in the Pyrococcus furiosus RAD system preserve epitopes antigenicity, immunogenicity, and virus-neutralizing …

Scientific Reports

Victor Bolsanelli Cioffi

Maria Fernanda de Castro-Amarante

Aleksei Lulla

Robert Andreata-Santos

Mario Costa Cruz

...

2023/10/5

Cover Feature: Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase (ChemBioChem 1/2023)

ChemBioChem

Umberto Maria Battisti

Chunxia Gao

Oscar Nilsson

Fady Akladios

Aleksei Lulla

...

2023/1/3

Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agents

Simon R Stockwell

Duncan E Scott

Gerhard Fischer

Estrella Guarino

Timothy PC

2023/3/22

Development of isoselenazolium chlorides as selective pyruvate kinase isoform M2 inhibitors

European Journal of Medicinal Chemistry

Pavels Dimitrijevs

Marina Makrecka-Kuka

Agnieszka Bogucka

Marko Hyvönen

Teodors Pantelejevs

...

2023/9/5

Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase

ChemBioChem

Umberto Maria Battisti

Chunxia Gao

Oscar Nilsson

Fady Akladios

Aleksei Lulla

...

2023/1/3

Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators

European Journal of Medicinal Chemistry

Amalyn Nain-Perez

Oscar Nilsson

Aleksei Lulla

Liliana Håversen

Paul Brear

...

2023/3/15

Structure-Guided Chemical Optimization of Bicyclic Peptide (Bicycle) Inhibitors of Angiotensin-Converting Enzyme 2

Journal of Medicinal Chemistry

Maximilian AJ Harman

Steven J Stanway

Heather Scott

Yuliya Demydchuk

Gustavo Arruda Bezerra

...

2023/7/11

Profiling human hypothalamic neurons reveals a candidate combination drug therapy for weight loss

bioRxiv

Hsiao-Jou Cortina Chen

Andrian Yang

Simone Mazzaferro

Iman Mali

Olivier Cahn

...

2023

Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade

Nature Communications

Juan Carlos Yam-Puc

Zhaleh Hosseini

Emily C Horner

Pehuén Pereyra Gerber

Nonantzin Beristain-Covarrubias

...

2023/6/27

Evolution of protease activation and specificity via alpha-2-macroglobulin-mediated covalent capture

Nature Communications

Philipp Knyphausen

Mariana Rangel Pereira

Paul Brear

Marko Hyvönen

Lutz Jermutus

...

2023/2/11

A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase

Chemical Science

Teodors Pantelejevs

Pedro Zuazua-Villar

Oliwia Koczy

Andrew J Counsell

Stephen J Walsh

...

2023

Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2

Nature communications

Katherine U Gaynor

Marina Vaysburd

Maximilian AJ Harman

Anna Albecka

Phillip Jeffrey

...

2023/6/16

Microfluidics-enabled fluorescence-activated cell sorting of single pathogen-specific antibody secreting cells for the rapid discovery of monoclonal antibodies

bioRxiv

Katrin Fischer

Aleksei Lulla

Tsz So

Pehuen Pereyra-Gerber

Matthew IJ Raybould

...

2023

Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors

Nature Chemical Biology

Maria Reinecke

Paul Brear

Larsen Vornholz

Benedict-Tilmann Berger

Florian Seefried

...

2023/10/30

Development of small cyclic peptides targeting the CK2α/β interface

Chemical Communications

Eleanor L Atkinson

Jessica Iegre

Claudio D’Amore

Paul Brear

Mauro Salvi

...

2022

See List of Professors in Marko Hyvönen University(University of Cambridge)

Co-Authors

H-index: 129
Tom L Blundell

Tom L Blundell

University of Cambridge

H-index: 69
David R Spring

David R Spring

University of Cambridge

H-index: 59
Florian Hollfelder

Florian Hollfelder

University of Cambridge

H-index: 28
elena baraldi

elena baraldi

Università degli Studi di Bologna

H-index: 14
Paul Brear

Paul Brear

University of Cambridge

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