David R Spring
University of Cambridge
H-index: 69
Europe-United Kingdom
Top articles of David R Spring
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Unlocking Amides: A General Method for the Self‐Immolative Release of Amide‐Containing Molecules | Angewandte Chemie | Thomas Wharton Felicity Crawshay‐Williams Tim Schober R Andres Floto David R Spring | 2024/3/27 |
CK2 Inhibitors Targeting Inside and Outside the Catalytic Box | Sophie Day-Riley Rebekah M West Paul D Brear Marko Hyvönen David R Spring | 2024/3/26 | |
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome | bioRxiv | Rohan Eapen Cynthia Okoye Christopher Stubbs Marianne Schimpl Thomas Tischer | 2024 |
Site-selective peptide functionalisation mediated via vinyl-triazine linchpins | Chemical Communications | Jack D Sydenham Hikaru Seki Sona Krajcovicova Linwei Zeng Tim Schober | 2024 |
Red-light modulated ortho-chloro azobenzene photoswitch for peptide stapling via aromatic substitution | RSC Chemical Biology | Mia Kapun F Javier Pérez-Areales Nicola Ashman Pamela JE Rowling Tim Schober | 2024 |
Identification of macrocyclic peptides which activate bacterial cylindrical proteases | RSC Medicinal Chemistry | Raoul Walther Linda M Westermann Sheiliza Carmali Sophie E Jackson Heike Brötz-Oesterhelt | 2023 |
The human proton pump inhibitors inhibit Mycobacterium tuberculosis rifampicin efflux and macrophage-induced rifampicin tolerance | Proceedings of the National Academy of Sciences | M Alexandra Lake Kristin N Adams Feilin Nie Elaine Fowler Amit K Verma | 2023/2/14 |
A cell-active peptide targeting the Nrf2/Keap1 protein-protein interaction | Soňa Krajčovičová Anders Gunnarsson Lisa Wissler Helena Käck Stefan Tangefjord | 2023/9/20 | |
Synthesis of sp 3-rich heterocyclic frameworks by a divergent synthesis strategy | Organic & Biomolecular Chemistry | SY Denedy A Thomas | 2023 |
Front Cover: Hybrid Androgen Receptor Inhibitors Outperform Enzalutamide and EPI‐001 in in vitro Models of Prostate Cancer Drug Resistance (ChemMedChem … | ChemMedChem | Radu Costin Bizga Nicolescu Zoe R Maylin Francisco Javier Pérez‐Areales Jessica Iegre Hardev S Pandha | 2023/1/17 |
Tryptophan in Multicomponent Petasis Reactions for Peptide Stapling and Late‐Stage Functionalisation | Angewandte Chemie International Edition | Sona Krajcovicova David R Spring | 2023/8/21 |
A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase | Chemical Science | Teodors Pantelejevs Pedro Zuazua-Villar Oliwia Koczy Andrew J Counsell Stephen J Walsh | 2023 |
Hybrid Androgen Receptor Inhibitors Outperform Enzalutamide and EPI‐001 in in vitro Models of Prostate Cancer Drug Resistance | ChemMedChem | Radu Costin Bizga Nicolescu Zoe R Maylin Francisco Javier Pérez‐Areales Jessica Iegre Hardev S Pandha | 2023/1/17 |
Development of constrained peptide inhibitors targeting an oncogenic E3 ubiquitin ligase | bioRxiv | Grasilda Zenkevičiūtė Wenshu Xu Jessica Iegre Hikaru Seki Yaw Sing Tan | 2023/4/27 |
Peroxide-cleavable linkers for antibody–drug conjugates | Chemical Communications | Nicola Ashman Jonathan D Bargh Stephen J Walsh Ryan D Greenwood Arnaud Tiberghien | 2023 |
A cell-active cyclic peptide targeting the Nrf2/Keap1 protein–protein interaction | Chemical Science | Jessica Iegre Sona Krajcovicova Anders Gunnarsson Lisa Wissler Helena Käck | 2023 |
Selective Aurora A-TPX2 interaction inhibitors have in vivo efficacy as targeted anti-mitotic agents | Simon R Stockwell Duncan E Scott Gerhard Fischer Estrella Guarino Timothy PC | 2023/3/22 | |
Disulfide re-bridging reagents for single-payload antibody-drug conjugates | Chemical Communications | Thomas A King Stephen J Walsh Mia Kapun Thomas Wharton Sona Krajcovicova | 2023 |
Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agents | Simon R Stockwell Duncan E Scott Gerhard Fischer Estrella Guarino Timothy PC | 2023/3/22 | |
Antibody dual-functionalisation enabled through a modular divinylpyrimidine disulfide rebridging strategy | Chemical Communications | Abigail R Hanby Stephen J Walsh Andrew J Counsell Nicola Ashman Kim T Mortensen | 2022 |
Co-Authors
