Marcellus Ubbink

Marcellus Ubbink

Universiteit Leiden

H-index: 48

Europe-Netherlands

About Marcellus Ubbink

Marcellus Ubbink, With an exceptional h-index of 48 and a recent h-index of 22 (since 2020), a distinguished researcher at Universiteit Leiden, specializes in the field of redox proteins, NMR, paramagnetism, enzyme, lactamase.

His recent articles reflect a diverse array of research interests and contributions to the field:

The effect of lipid composition on the thermal stability of nanodiscs

Conserved proline residues prevent dimerization and aggregation in the β‐lactamase BlaC

Positive epistasis drives clavulanic acid resistance in double mutant libraries of BlaC β-lactamase

Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase

Asp179 in the class A β‐lactamase from Mycobacterium tuberculosis is a conserved yet not essential residue due to epistasis

Mycobacterium tuberculosis β-lactamase variant reduces sensitivity to ampicillin/avibactam in a zebrafish-Mycobacterium marinum model of tuberculosis

Rigidified and hydrophilic DOTA-like lanthanoid ligands: Design, synthesis, and dynamic properties

The roles of highly conserved, non‐catalytic residues in class A β‐lactamases

Marcellus Ubbink Information

University

Position

Professor of Protein Chemistry

Citations(all)

7519

Citations(since 2020)

1859

Cited By

6580

hIndex(all)

48

hIndex(since 2020)

22

i10Index(all)

126

i10Index(since 2020)

60

Email

University Profile Page

Universiteit Leiden

Google Scholar

View Google Scholar Profile

Marcellus Ubbink Skills & Research Interests

redox proteins

NMR

paramagnetism

enzyme

lactamase

Top articles of Marcellus Ubbink

Title

Journal

Author(s)

Publication Date

The effect of lipid composition on the thermal stability of nanodiscs

Biochimica et Biophysica Acta (BBA)-Biomembranes

Tim GJ Knetsch

Marcellus Ubbink

2024/1/1

Conserved proline residues prevent dimerization and aggregation in the β‐lactamase BlaC

Protein Science

A Chikunova

MP Manley

CN Heijjer

CS Drenth

AJ Cramer‐Blok

...

2024/4

Positive epistasis drives clavulanic acid resistance in double mutant libraries of BlaC β-lactamase

Communications Biology

Marko Radojković

Marcellus Ubbink

2024/2/17

Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase

International Journal of Biological Macromolecules

Jing Sun

Aleksandra Chikunova

Aimee L Boyle

Patrick Voskamp

Monika Timmer

...

2023/10/1

Asp179 in the class A β‐lactamase from Mycobacterium tuberculosis is a conserved yet not essential residue due to epistasis

The FEBS Journal

Ilona van Alen

Aleksandra Chikunova

Danny B van Zanten

Amber A de Block

Monika Timmer

...

2023/10

Mycobacterium tuberculosis β-lactamase variant reduces sensitivity to ampicillin/avibactam in a zebrafish-Mycobacterium marinum model of tuberculosis

Scientific reports

Ilona van Alen

Mayra A Aguirre García

Janneke J Maaskant

Coenraad P Kuijl

Wilbert Bitter

...

2023/9/16

Rigidified and hydrophilic DOTA-like lanthanoid ligands: Design, synthesis, and dynamic properties

Inorganic Chemistry

Qing Miao

René Dekkers

Karthick Babu Sai Sankar Gupta

Mark Overhand

Rubin Dasgupta

...

2023/2/17

The roles of highly conserved, non‐catalytic residues in class A β‐lactamases

Protein Science

Aleksandra Chikunova

Marcellus Ubbink

2022/6

Paramagnetic chemical probes for studying biological macromolecules

Qing Miao

Christoph Nitsche

Henry Orton

Mark Overhand

Gottfried Otting

...

2022/1/27

Enhancing the population of the encounter complex affects protein complex formation efficiency

The FEBS Journal

Antonella Di Savino

Johannes M Foerster

G Matthias Ullmann

Marcellus Ubbink

2022/1

The resting oxidized state of small laccase analyzed with paramagnetic NMR spectroscopy

ChemPhysChem

Rubin Dasgupta

Karthick BSS Gupta

Huub JM de Groot

Marcellus Ubbink

2021/4/19

Partial opening of cytochrome P450cam (CYP101A1) is driven by allostery and putidaredoxin binding

Biochemistry

Simon P Skinner

Alec H Follmer

Marcellus Ubbink

Thomas L Poulos

Jeanine J Houwing-Duistermaat

...

2021/9/14

Two β-lactamase variants with reduced clavulanic acid inhibition display different millisecond dynamics

Antimicrobial Agents and Chemotherapy

Wouter Elings

Aleksandra Chikunova

Danny B van Zanten

Ralphe Drenth

Misbha Ud Din Ahmad

...

2021/7/16

Corrigendum: A Two‐Armed Probe for In‐Cell DEER Measurements on Proteins

Chemistry (Weinheim an der Bergstrasse, Germany)

Qing Miao

Enrico Zurlo

Donny de Bruin

Joeri AJ Wondergem

SP Skinner

...

2021/4/4

The G132S Mutation Enhances the Resistance of Mycobacterium tuberculosis β-Lactamase against Sulbactam

Biochemistry

Ilona van Alen

Aleksandra Chikunova

Adil A Safeer

Misbha Ud Din Ahmad

Anastassis Perrakis

...

2021/7/12

Protein dynamics influence the enzymatic activity of phospholipase A/Acyltransferases 3 and 4

Biochemistry

Soumya Deep Chatterjee

Juan Zhou

Rubin Dasgupta

Anneloes Cramer-Blok

Monika Timmer

...

2021/3/22

Dipolar dephasing for structure determination in a paramagnetic environment

Solid State Nuclear Magnetic Resonance

Rubin Dasgupta

Karthick BSS Gupta

Derek Elam

Marcellus Ubbink

Huub JM de Groot

2021/6/1

The charge distribution on a protein surface determines whether productive or futile encounter complexes are formed

Biochemistry

Antonella Di Savino

Johannes M Foerster

G Matthias Ullmann

Marcellus Ubbink

2021/3/1

Novel anti-repression mechanism of H-NS proteins by a phage protein

Nucleic Acids Research

Fredj Ben Bdira

Amanda M Erkelens

Liang Qin

Alexander N Volkov

Andrew M Lippa

...

2021/10/11

Tuning the transglycosylation reaction of a GH11 xylanase by a delicate enhancement of its thumb flexibility

ChemBioChem

Kim Marneth

Hans van den Elst

Anneloes Cramer‐Blok

Jeroen Codee

Hermen S Overkleeft

...

2021/5/14

See List of Professors in Marcellus Ubbink University(Universiteit Leiden)

Co-Authors

H-index: 95
Claudio Luchinat

Claudio Luchinat

Università degli Studi di Firenze

H-index: 87
Gottfried Otting

Gottfried Otting

Australian National University

H-index: 72
Christopher Howe

Christopher Howe

University of Cambridge

H-index: 66
Sung-Kun (Sean) Kim

Sung-Kun (Sean) Kim

Northeastern State University

H-index: 64
Geert J.P.L. Kops

Geert J.P.L. Kops

Universiteit Utrecht

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