Luhua Lai
Peking University
H-index: 68
Asia-China
Top articles of Luhua Lai
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Accelerating Discovery of Novel and Bioactive Ligands With Pharmacophore-Informed Generative Models | arXiv preprint arXiv:2401.01059 | Weixin Xie Jianhang Zhang Qin Xie Chaojun Gong Youjun Xu | 2024/1/2 |
DiffBindFR: An SE (3) Equivariant Network for Flexible Protein-Ligand Docking | Chemical Science | Jintao Zhu Zhonghui Gu Jianfeng Pei Luhua Lai | 2024 |
All-atom protein sequence design based on geometric deep learning | bioRxiv | Jiale Liu Zheng Guo Changsheng Zhang Luhua Lai | 2024 |
Discovery of 3-oxo-1, 2, 3, 4-tetrahydropyrido [1, 2-a] pyrazin derivatives as SARS-CoV-2 main protease inhibitors through virtual screening and biological evaluation | Bioorganic & Medicinal Chemistry Letters | Xiaodong Dou Qi Sun Yameng Liu Yangbin Lu Caifang Zhang | 2024/1/1 |
Photoaffinity labeling coupled with proteomics identify PDI-ADAM17 module is targeted by (−)-vinigrol to induce TNFR1 shedding and ameliorate rheumatoid arthritis in mice | Cell Chemical Biology | Yinhua Zhu Lu Wang Jing Li Yuan Zhao Xuerong Yu | 2024 |
DeepRLI: A Multi-objective Framework for Universal Protein--Ligand Interaction Prediction | arXiv preprint arXiv:2401.10806 | Haoyu Lin Shiwei Wang Jintao Zhu Yibo Li Jianfeng Pei | 2024/1/19 |
In silico protein function prediction: the rise of machine learning-based approaches | Jiaxiao Chen Zhonghui Gu Luhua Lai Jianfeng Pei | 2023/12/15 | |
Coevolution-based prediction of key allosteric residues for protein function regulation | Elife | Juan Xie Weilin Zhang Xiaolei Zhu Minghua Deng Luhua Lai | 2023/2/17 |
Small molecules in regulating protein phase separation: Regulating protein phase separation by small molecules | Acta Biochimica et Biophysica Sinica | Siyang Li Yanyan Wang Luhua Lai | 2023/7/7 |
DiffBind: A SE (3) Equivariant Network for Accurate Full-Atom Semi-Flexible Protein-Ligand Docking | arXiv preprint arXiv:2311.15201 | Jintao Zhu Zhonghui Gu Jianfeng Pei Luhua Lai | 2023/11/26 |
Graph Kernel Learning for Predictive Toxicity Models | Youjun Xu Chia-Han Chou Ningsheng Han Jianfeng Pei Luhua Lai | 2023/2/8 | |
Hierarchical graph transformer with contrastive learning for protein function prediction | Bioinformatics | Zhonghui Gu Xiao Luo Jiaxiao Chen Minghua Deng Luhua Lai | 2023/1/1 |
Rational drug design targeting intrinsically disordered proteins | Hanping Wang Ruoyao Xiong Luhua Lai | 2023/11 | |
QuoteTarget: A sequence‐based transformer protein language model to identify potentially druggable protein targets | Protein Science | Jiaxiao Chen Zhonghui Gu Youjun Xu Minghua Deng Luhua Lai | 2023/2 |
ssDNA accessibility of Rad51 is regulated by orchestrating multiple RPA dynamics | Nature Communications | Jiawei Ding Xiangting Li Jiangchuan Shen Yiling Zhao Shuchen Zhong | 2023/6/30 |
Designing Cyclic-Constrained Peptides to Inhibit Human Phosphoglycerate Dehydrogenase | Molecules | Xiaoyu Qing Qian Wang Hanyu Xu Pei Liu Luhua Lai | 2023/9/4 |
Intrinsic disorder and allosteric regulation | Qiaojing Huang Limin Chen Luhua Lai Zhirong Liu | 2023/1/1 | |
Toward In Silico Design of Protein–Protein Interaction Stabilizers | Jintao Zhu Luhua Lai Jianfeng Pei | 2023/5/9 | |
Visualizing single-molecule conformational transition and binding dynamics of intrinsically disordered proteins | Nature Communications | Wenzhe Liu Limin Chen Dongbao Yin Zhiheng Yang Jianfei Feng | 2023/8/25 |
How protein topology controls allosteric regulations | The Journal of Chemical Physics | Juan Xie Gaoxiang Pan Yibo Li Luhua Lai | 2023/3/14 |
Co-Authors
