Luca Pinello
Harvard University
H-index: 46
North America-United States
Top articles of Luca Pinello
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
DNA-Diffusion: Leveraging Generative Models for Controlling Chromatin Accessibility and Gene Expression via Synthetic Regulatory Elements | bioRxiv | Lucas Ferreira DaSilva Simon Senan Zain Munir Patel Aniketh Janardhan Reddy Sameer Gabbita | 2024 |
CRISPR PERSIST-On enables heritable and fine-tunable human gene activation | bioRxiv | Yugyoung Esther Tak Jonathan Y Hsu Justine Shih Hayley T Schultz Ivy T Nguyen | 2024 |
Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification | medRxiv | Jayoung Ryu Sam Barkal Tian Yu Martin Jankowiak Yunzhuo Zhou | 2023/9/10 |
Statistical inference with a manifold-constrained RNA velocity model uncovers cell cycle speed modulations | bioRxiv | Alex R Lederer Maxine Leonardi Lorenzo Talamanca Antonio Herrera Colas Droin | 2024 |
Defining and benchmarking open problems in single-cell analysis | Malte Luecken Scott Gigante Daniel Burkhardt Robrecht Cannoodt Daniel Strobl | 2024/4/4 | |
Non-genetic determinants driving the evolutional trajectories of drug-tolerant-persisters in KRAS Non-small cell lung cancer | Cancer Research | Chendi Li Christopher J Graser Qian Qin Anahita Nimbalkar Usman Syed | 2024/3/22 |
Benchmarking computational methods to identify spatially variable genes and peaks | Biorxiv | Zhijian Li Zain M Patel Dongyuan Song Guanao Yan Jingyi Jessica Li | 2023 |
Modeling single-cell dynamics using stochastic generative models based on neural differential equations | Cancer Research | Michael E Vinyard Anders W Rasmussen Ruitong Li Luca Pinello Gad Getz | 2023/4/4 |
Loss-of-function lesions impact B-cell development and fitness but are insufficient to drive CLL in mouse models | Blood Advances | Elisa ten Hacken Shanye Yin Robert Redd María Hernández Sánchez Kendell Clement | 2023/8/22 |
Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells | BioRxiv | Jing Zeng My Anh Nguyen Pengpeng Liu Lucas Ferreira da Silva Linda Y Lin | 2023 |
Chromatin modification driving sub-clonal resistance to KRAS G12C combination therapies in KRAS mutant non-small cell lung cancer | Cancer Research | Chendi Li Qian Qin Mohammed Usman Syed Anahita Nimbalkar Barbara Karakyriakou | 2023/4/4 |
Systems and Methods for Stable and Heritable Alteration by Precision Editing (SHAPE) | 2023/8/3 | ||
Novel mechanism of MYC deregulation in Multiple Myeloma | bioRxiv | Mahshid Rahmat Kendell Clement Jean-Baptiste Alberge Romanos Sklavenitis-Pistofidis Rohan Kodgule | 2023 |
A molecular glue approach to control the half-life of CRISPR-based technologies | bioRxiv | Vedagopuram Sreekanth Max Jan Kevin T Zhao Donghyun Lim Jessie R Davis | 2023/3/20 |
Integrative dissection of gene regulatory elements at base resolution | Cell Genomics | Zeyu Chen Nauman Javed Molly Moore Jingyi Wu Gary Sun | 2023/6/14 |
Human genetic diversity alters off-target outcomes of therapeutic gene editing | Nature genetics | Samuele Cancellieri Jing Zeng Linda Yingqi Lin Manuel Tognon My Anh Nguyen | 2023/1 |
Precise DNA cleavage using CRISPR-SpRYgests | Nature biotechnology | Kathleen A Christie Jimmy A Guo Rachel A Silverstein Roman M Doll Megumu Mabuchi | 2023/3 |
SIMBA: single-cell embedding along with features | Nature Methods | Huidong Chen Jayoung Ryu Michael E Vinyard Adam Lerer Luca Pinello | 2023/5/29 |
Abstract B080: Non-genetic determinants driving sub-clonal resistance to KRAS G12C combination therapies in KRAS mutant non-small cell lung cancer | Molecular Cancer Therapeutics | Chendi Li Christopher J Graser Qian Qin Usman M Syed Barbara Karakyriakou | 2023/12/1 |
scDiffEq: drift-diffusion modeling of single-cell dynamics with neural stochastic differential equations | bioRxiv | Michael Edward Vinyard Anders Rasmussen Ruitong Li Gad Getz Luca Pinello | 2023 |
Co-Authors
