Li Lan

Li Lan

University of Pittsburgh

H-index: 48

North America-United States

About Li Lan

Li Lan, With an exceptional h-index of 48 and a recent h-index of 33 (since 2020), a distinguished researcher at University of Pittsburgh, specializes in the field of DNA/RNA, cancer, recombination, transcription.

His recent articles reflect a diverse array of research interests and contributions to the field:

Revisiting Aurora Kinase B: A promising therapeutic target for cancer therapy

The RNA m5C modification in R-loops as an off switch of Alt-NHEJ

The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy …

The Fanconi Anemia pathway protein complex FANCI/FANCD2 couples the DNA damage response to R-loop regulation through SRSF1-mediated mRNA export

Complex Formation between FANCD2 and the Splicing Factor SRSF1 Helps Prevent R-Loop Accumulation through mRNA Export Regulation

Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids

FMRP promotes transcription-coupled homologous recombination via facilitating TET1-mediated m5C RNA modification demethylation

DNA repair defects in cancer and therapeutic opportunities

Li Lan Information

University

Position

___

Citations(all)

6442

Citations(since 2020)

3317

Cited By

4857

hIndex(all)

48

hIndex(since 2020)

33

i10Index(all)

74

i10Index(since 2020)

68

Email

University Profile Page

University of Pittsburgh

Google Scholar

View Google Scholar Profile

Li Lan Skills & Research Interests

DNA/RNA

cancer

recombination

transcription

Top articles of Li Lan

Title

Journal

Author(s)

Publication Date

Revisiting Aurora Kinase B: A promising therapeutic target for cancer therapy

Naga Rajiv Lakkaniga

Zhengyu Wang

Yao Xiao

Anupreet Kharbanda

Li Lan

...

2024/3

The RNA m5C modification in R-loops as an off switch of Alt-NHEJ

Nature Communications

Haibo Yang

Emily M Lachtara

Xiaojuan Ran

Jessica Hopkins

Parasvi S Patel

...

2023/9/30

The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy …

Oncogene

Zhiping Li

Xuanmao Jiao

A Gordon Robertson

Gabriele Di Sante

Anthony W Ashton

...

2023/6/2

The Fanconi Anemia pathway protein complex FANCI/FANCD2 couples the DNA damage response to R-loop regulation through SRSF1-mediated mRNA export

Cancer Research

Anne Olazabal-Herrero

Fengshan Liang

Arijit Dutta

Yuxin Huang

Zhuobin Liang

...

2023/4/4

Complex Formation between FANCD2 and the Splicing Factor SRSF1 Helps Prevent R-Loop Accumulation through mRNA Export Regulation

Blood

Anne Olazabal Herrero

Fengshan Liang

Arijit Dutta

Yuxin Huang

Zhuobin Liang

...

2022/11/15

Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids

Eva Petermann

Li Lan

Lee Zou

2022/8

FMRP promotes transcription-coupled homologous recombination via facilitating TET1-mediated m5C RNA modification demethylation

Proceedings of the National Academy of Sciences

Haibo Yang

Yumin Wang

Yufei Xiang

Tribhuwan Yadav

Jian Ouyang

...

2022/3/22

DNA repair defects in cancer and therapeutic opportunities

Jessica L Hopkins

Li Lan

Lee Zou

2022/3/1

RNA transcripts stimulate homologous recombination by forming DR-loops

Nature

Jian Ouyang

Tribhuwan Yadav

Jia-Min Zhang

Haibo Yang

Esther Rheinbay

...

2021/6/10

Alternative lengthening of telomeres is a self-perpetuating process in ALT-associated PML bodies

Molecular cell

Jia-Min Zhang

Marie-Michelle Genois

Jian Ouyang

Li Lan

Lee Zou

2021/3/4

Ubiquitination-mediated degradation of TRDMT1 regulates homologous recombination and therapeutic response

NAR cancer

Xiaolan Zhu

Xiangyu Wang

Wei Yan

Haibo Yang

Yufei Xiang

...

2021/3/1

The Forkhead-like protein Dach1 governs sensitivity to WEE1 kinase and PARP inhibitors

Cancer Research

Zhiping Li

Xuanmao Jiao

A Gordon Robertson

Anthony W Ashton

Andrew Kossenkov

...

2021/7/1

m5C modification of mRNA serves a DNA damage code to promote homologous recombination

Nature communications

Hao Chen

Haibo Yang

Xiaolan Zhu

Tribhuwan Yadav

Jian Ouyang

...

2020/6/5

Resolution of ROS‐induced G‐quadruplexes and R‐loops at Transcriptionally Active Sites Is Dependent on BLM Helicase

FEBS letters

Jun Tan

Xiangyu Wang

Laiyee Phoon

Haibo Yang

Li Lan

2020/5

The DNA secondary structures at telomeres and genome instability

Jun Tan

Li Lan

2020/3/26

cGAS suppresses genomic instability as a decelerator of replication forks

Science advances

Hao Chen

Hao Chen

Jiamin Zhang

Yumin Wang

Antoine Simoneau

...

2020/10/14

An R-loop-initiated CSB–RAD52–POLD3 pathway suppresses ROS-induced telomeric DNA breaks

Nucleic acids research

Jun Tan

Meihan Duan

Tribhuwan Yadav

Laiyee Phoon

Xiangyu Wang

...

2020/2/20

The deacetylase SIRT6 promotes the repair of UV-induced DNA damage by targeting DDB2

Nucleic Acids Research

Anke Geng

Huanyin Tang

Jin Huang

Zhen Qian

Nan Qin

...

2020/9/18

Cigarette smoke exposure enhances transforming acidic coiled-coil–containing protein 2 turnover and thereby promotes emphysema

JCI insight

Rama K Mallampalli

Xiuying Li

Jun-Ho Jang

Tomasz Kaminski

Aki Hoji

...

2020/1/1

An ordered assembly of MYH glycosylase, SIRT6 protein deacetylase, and Rad9-Rad1-Hus1 checkpoint clamp at oxidatively damaged telomeres

Aging (Albany NY)

Jun Tan

Xiangyu Wang

Bor-Jang Hwang

Rex Gonzales

Olivia Konen

...

2020/9/9

See List of Professors in Li Lan University(University of Pittsburgh)