Leah E. Cowen

Leah E. Cowen

University of Toronto

H-index: 56

North America-Canada

About Leah E. Cowen

Leah E. Cowen, With an exceptional h-index of 56 and a recent h-index of 44 (since 2020), a distinguished researcher at University of Toronto, specializes in the field of Functional Genomics, Chemical Biology, Fungal Pathogenesis, Antifungal Drug Development & Resistance.

His recent articles reflect a diverse array of research interests and contributions to the field:

Advancements and challenges in antifungal therapeutic development

Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity

A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen Candida albicans

Selective control of parasitic nematodes using bioactivated nematicides

Potent Antifungal Activity of Penta-O-galloyl-β-d-Glucose against Drug-Resistant Candida albicans, Candida auris, and Other Non-albicans Candida Species

Functional genomic analysis of Candida albicans protein kinases reveals modulators of morphogenesis in diverse environments

Imidazopyridine Amides: Synthesis, Mycobacterium smegmatis CIII2CIV2 Supercomplex Binding, and In Vitro Antimycobacterial Activity

Multifactor transcriptional control of alternative oxidase induction integrates diverse environmental inputs to enable fungal virulence

Leah E. Cowen Information

University

Position

Professor & Chair Department of Molecular Genetics

Citations(all)

13121

Citations(since 2020)

7156

Cited By

9043

hIndex(all)

56

hIndex(since 2020)

44

i10Index(all)

110

i10Index(since 2020)

103

Email

University Profile Page

University of Toronto

Google Scholar

View Google Scholar Profile

Leah E. Cowen Skills & Research Interests

Functional Genomics

Chemical Biology

Fungal Pathogenesis

Antifungal Drug Development & Resistance

Top articles of Leah E. Cowen

Title

Journal

Author(s)

Publication Date

Advancements and challenges in antifungal therapeutic development

Emily Puumala

Sara Fallah

Nicole Robbins

Leah E Cowen

2024/1/31

Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity

Cell Chemical Biology

Emily Puumala

David Sychantha

Elizabeth Lach

Shawn Reeves

Sunna Nabeela

...

2024/2/20

A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen Candida albicans

Microbiology Spectrum

Sara Fallah

Dustin Duncan

Kyle D Reichl

Michael J Smith

Wenyu Wang

...

2024/2/20

Selective control of parasitic nematodes using bioactivated nematicides

Nature

Andrew R Burns

Rachel J Baker

Megan Kitner

Jessica Knox

Brittany Cooke

...

2023/6/1

Potent Antifungal Activity of Penta-O-galloyl-β-d-Glucose against Drug-Resistant Candida albicans, Candida auris, and Other Non-albicans Candida Species

ACS Infectious Diseases

Lewis Marquez

Yunjin Lee

Dustin Duncan

Luke Whitesell

Leah E Cowen

...

2023/8/22

Functional genomic analysis of Candida albicans protein kinases reveals modulators of morphogenesis in diverse environments

Iscience

Yunjin Lee

Saif Hossain

Jessie MacAlpine

Nicole Robbins

Leah E Cowen

2023/3/17

Imidazopyridine Amides: Synthesis, Mycobacterium smegmatis CIII2CIV2 Supercomplex Binding, and In Vitro Antimycobacterial Activity

ACS omega

Rana Abdelaziz

Justin M Di Trani

Henok Sahile

Lea Mann

Adrian Richter

...

2023/5/18

Multifactor transcriptional control of alternative oxidase induction integrates diverse environmental inputs to enable fungal virulence

Nature Communications

Zhongle Liu

Pauline Basso

Saif Hossain

Sean D Liston

Nicole Robbins

...

2023/7/27

Respiration supports intraphagosomal filamentation and escape of Candida albicans from macrophages

Mbio

Nicola T Case

Johannes Westman

Michael T Hallett

Jonathan Plumb

Aiman Farheen

...

2023/12/19

Diverse Plant-Parasitic Nematodes are Selectively Killed by Oxadiazole Thioether Pro-Nematicides

bioRxiv

Jessica Knox

Andrew R Burns

Brittany Cooke

Savina R Cammalleri

Megan Kitner

...

2023

1011 Potent antifungal activity of pentagalloyl glucose against drug-resistant candida albicans, candida auris, and other non-albicans candida species

Journal of Investigative Dermatology

L Marquez

Y Lee

D Duncan

L Whitesell

L Cowen

...

2023/5/1

Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity

Cell Chemical Biology

Kali R Iyer

Sheena C Li

Nicole M Revie

Jennifer W Lou

Dustin Duncan

...

2023/7/20

DYRK-family kinases regulate Candida albicans morphogenesis and virulence through the Ras1/PKA pathway

MBio

Jessie MacAlpine

Zhongle Liu

Saif Hossain

Luke Whitesell

Nicole Robbins

...

2023/12/19

Interactions Between Intracellular Fungal Pathogens and Host Phagocytes

Nicola T Case

Nicole Robbins

Leah E Cowen

2023/1/1

Bacterial‐fungal interactions and their impact on microbial pathogenesis

Jessie MacAlpine

Nicole Robbins

Leah E Cowen

2023/5

Molecular mechanisms governing antifungal drug resistance

Yunjin Lee

Nicole Robbins

Leah E Cowen

2023/7/17

Fungal modulators

2023/10/3

Ent2 Governs Morphogenesis and Virulence in Part through Regulation of the Cdc42 Signaling Cascade in the Fungal Pathogen Candida albicans

Mbio

Emma Lash

Victoria Prudent

Peter J Stogios

Alexei Savchenko

Suzanne M Noble

...

2023/4/25

Construction of Candida albicans strains with ATP-analog-sensitive protein kinase A and Hog1

Msphere

Zhongle Liu

Jessie MacAlpine

Nicole Robbins

Leah E Cowen

2023/4/11

Roles of Hsp90 in Candida albicans morphogenesis and virulence

Nicole Robbins

Leah E Cowen

2023/10/1

See List of Professors in Leah E. Cowen University(University of Toronto)