Laura Gathercole
Oxford Brookes University
H-index: 22
Europe-United Kingdom
Top articles of Laura Gathercole
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Androgens potently regulate sterol 12 [alpha]-hydroxylase (CYP8B1) expression in mouse and human liver | Endocrine Abstracts | Tom Potter Elena Gangitano Jenny Visser Laura Gathercole Jeremy Tomlinson | 2023/10/31 |
Female AKR1D1 knockout mice are protected against diet induced obesity and insulin resistance but not hepatic steatosis | Endocrine Abstracts | Maira Bailey Tom Potter Dean Larner Stuart Morgan Gareth Lavery | 2023/10/31 |
Localisation of the steroid 5 [beta]-reductase in hepatoma cells | Endocrine Abstracts | Tom Potter Jeremy Tomlinson Laura Gathercole | 2023/5/2 |
AKR1D1 knockdown identifies 7 [alpha]-hydroxy-3-oxo-4-cholestenoic acid (7-HOCA) as a driver of metabolic dysfunction and hepatocellular cancer risk in patients with non … | Endocrine abstracts | Nikolaos Nikolaou Anastasia Arvaniti Fabio Sanna Niall Dempster Laura Gathercole | 2022/5/7 |
7 [alpha]-hydroxy-3-oxo-4-cholestenoic acid (7-HOCA) is a novel AKR1D1 substrate driving metabolic dysfunction and hepatocellular cancer risk in patients with non-alcoholic … | Endocrine Abstracts | Nikolaos Nikolaou Anastasia Arvaniti Fabio Sanna Niall Dempster Laura Gathercole | 2022/10/27 |
The American lifestyle-induced obesity syndrome diet (ALIOS) in mice alters the diversity and composition of the gut microbiome | Endocrine Abstracts | Tom Potter Anastasia Arvaniti Shelley Harris Jeremy Tomlinson Laura Gathercole | 2022/10/27 |
Dysregulation of cytochrome P450 oxidoreductase (POR) in NAFLD and hepatocellular carcinoma; evidence from clinical, rodent and cellular models | Endocrine Abstracts | Nikolaos Nikolaou Laura Gathercole Shelley Harris Niall Dempster Ahmad Moolla | 2022/5/7 |
AKR1D1 knockout mice develop a sex-dependent metabolic phenotype | Journal of Endocrinology | Laura L Gathercole Nikolaos Nikolaou Shelley E Harris Anastasia Arvaniti Toryn M Poolman | 2022/6/1 |
Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents | Metabolism open | Jonathan M Hazlehurst Teegan Reina Lim Catriona Charlton Jack J Miller Laura L Gathercole | 2022/6/1 |
Differential localisation of the A-ring reductases in human hepatocytes: implications for substrate preference and utilisation | Endocrine Abstracts | Tom Potter Nikolaos Nikolaou Nellie Loh Jeremy Tomlinson Laura Gathercole | 2022/5/7 |
11β-HSD1 contributes to age-related metabolic decline in male mice | Journal of Endocrinology | Stuart A Morgan Laura L Gathercole Zaki K Hassan-Smith Jeremy Tomlinson Paul M Stewart | 2022/12/1 |
Akr1d1-/- mice have a sexually dimorphic metabolic phenotype with reduced fat mass, increased insulin sensitivity and hypertriglyceridemia in males | bioRxiv | Laura L Gathercole Nikolaos Nikolaou Anastasia Arvaniti Shelley E Harris Toryn M Poolman | 2021/2/2 |
5 [beta]-reductase is downregulated in patients with non-alcoholic fatty liver disease and hepatocellular carcinoma and controls metabolic and proliferative phenotype through … | Endocrine Abstracts | Nikolaos Nikolaou Anastasia Arvaniti Fabio Sanna Michael Saikali Niall Dempster | 2021/10/18 |
The american lifestyle induced obesity syndrome (ALIOS) diet induces an increase in intestinal permeability and exacerbates inflammation in female and male mice via the TLR4 … | Endocrine Abstracts | Arvaniti Anastasia Nikolaos Nikolaou Shelley Harris Roger Cox Daniele Corridoni | 2021/5/15 |
Differential activity and expression of human 5β-reductase (AKR1D1) splice variants | Journal of molecular endocrinology | Nathan Appanna Hylton Gibson Elena Gangitano Niall J Dempster Karen Morris | 2021/4/1 |
Liver and Biliary Tract Physiology/Pathophysiology: The American lifestyle-induced obesity syndrome diet in male and female rodents recapitulates the clinical and … | American Journal of Physiology-Gastrointestinal and Liver Physiology | Guangyan Wei Ping An Kahini A Vaid Imad Nasser Pinzhu Huang | 2020/1/1 |
Aldo-keto reductase (AKR) 1C1–a potential driver of cell cycle progression in hepatocellular carcinoma | Endocrine Abstracts | Nikolaos Nikolaou Anastasia Arvaniti Laura Gathercole Leanne Hodson Jeremy Tomlinson | 2020/8/21 |
Female AKR1D1 knockout mice have impaired intestinal health with evidence of gut dybiosis, increased gut permeability and an increased incidence of colon cancer | Endocrine Abstracts | Anastasia Arvaniti Shelley Harris Nikolaos Nikolaou Tom Potter Roger Cox | 2020/8/21 |
Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo | Journal of Endocrinology | Nikolaos Nikolaou Anastasia Arvaniti Nathan Appanna Anna Sharp Beverly A Hughes | 2020/5/1 |
