Lars Nitschke

About Lars Nitschke

Lars Nitschke, With an exceptional h-index of 47 and a recent h-index of 27 (since 2020), a distinguished researcher at Friedrich-Alexander-Universität Erlangen-Nürnberg, specializes in the field of B-cell immunology, autoimmunity, Siglecs.

His recent articles reflect a diverse array of research interests and contributions to the field:

P12. 08 Targeting tumor-reduced drug accessibility to counteract organ-specific resistance to anti-CD22 immunotoxins

The role of Siglec-G on B cells in autoimmune disease and leukemia

Structure and Signalling Function of the B-Cell Antigen Receptor and Its Coreceptors

The inhibitory receptor Siglec‐G controls the severity of chronic lymphocytic leukemia

IL-4 induces CD22 expression to restrain the effector program of self-reactive virtual memory T cells

Epistatic effects of siglec-G and DNase1 or DNase1l3 deficiencies in the development of systemic lupus erythematosus

B-cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia

Targeting Human CD22/Siglec-2 with Dimeric Sialosides as Novel Oligosaccharide Mimetics

Lars Nitschke Information

University

Position

Lehrstuhl Genetik

Citations(all)

6884

Citations(since 2020)

2170

Cited By

5581

hIndex(all)

47

hIndex(since 2020)

27

i10Index(all)

88

i10Index(since 2020)

62

Email

University Profile Page

Google Scholar

Lars Nitschke Skills & Research Interests

B-cell immunology

autoimmunity

Siglecs

Top articles of Lars Nitschke

P12. 08 Targeting tumor-reduced drug accessibility to counteract organ-specific resistance to anti-CD22 immunotoxins

2024/3/1

The role of Siglec-G on B cells in autoimmune disease and leukemia

Seminars in Arthritis and Rheumatism

2024/2/1

Lars Nitschke
Lars Nitschke

H-Index: 26

Structure and Signalling Function of the B-Cell Antigen Receptor and Its Coreceptors

2024/1/1

Lars Nitschke
Lars Nitschke

H-Index: 26

The inhibitory receptor Siglec‐G controls the severity of chronic lymphocytic leukemia

EMBO reports

2023/8/3

Lars Nitschke
Lars Nitschke

H-Index: 26

IL-4 induces CD22 expression to restrain the effector program of self-reactive virtual memory T cells

Research Square

2023/4/6

Epistatic effects of siglec-G and DNase1 or DNase1l3 deficiencies in the development of systemic lupus erythematosus

Frontiers in Immunology

2023/3/8

Lars Nitschke
Lars Nitschke

H-Index: 26

B-cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia

Haematologica

2022/8/8

Lars Nitschke
Lars Nitschke

H-Index: 26

Hassan Jumaa
Hassan Jumaa

H-Index: 35

Targeting Human CD22/Siglec-2 with Dimeric Sialosides as Novel Oligosaccharide Mimetics

Journal of Medicinal Chemistry

2022/7/26

Martin Frank
Martin Frank

H-Index: 18

Lars Nitschke
Lars Nitschke

H-Index: 26

Sialic acids on B cells are crucial for their survival and provide protection against apoptosis

Proceedings of the National Academy of Sciences

2022/6/21

Coordinated changes in glycosylation regulate the germinal center through CD22

Cell reports

2022/3/15

Jaesoo Jung
Jaesoo Jung

H-Index: 4

Lars Nitschke
Lars Nitschke

H-Index: 26

The inhibitory coreceptor CD22 restores B cell signaling by developmentally regulating Cd45−/− immunodeficient B cells

Science signaling

2022/3/1

Lars Nitschke
Lars Nitschke

H-Index: 26

Human CD22-transgenic, primary murine lymphoma challenges immunotherapies in organ-specific tumor microenvironments

International Journal of Molecular Sciences

2021/9/28

Lars Nitschke
Lars Nitschke

H-Index: 26

Siglec-h-deficient mice show enhanced type I IFN responses, but do not develop autoimmunity after influenza or LCMV infections

Frontiers in Immunology

2021/8/23

Lars Nitschke
Lars Nitschke

H-Index: 26

CD22 controls germinal center B cell receptor signaling, which influences plasma cell and memory B cell output

The Journal of Immunology

2021/8/15

Lars Nitschke
Lars Nitschke

H-Index: 26

Intravital quantification reveals dynamic calcium concentration changes across B cell differentiation stages

Elife

2021/3/22

Frank Kirchhoff
Frank Kirchhoff

H-Index: 44

Lars Nitschke
Lars Nitschke

H-Index: 26

A CD22–Shp1 phosphatase axis controls integrin β7 display and B cell function in mucosal immunity

Nature immunology

2021/3

The human sialic acid-binding immunoglobulin-like lectin Siglec-9 and its murine homolog Siglec-E control osteoclast activity and bone resorption

Bone

2021/2/1

Siglec-15 on osteoclasts is crucial for bone erosion in serum-transfer arthritis

The Journal of Immunology

2020/11/15

Lars Nitschke
Lars Nitschke

H-Index: 26

Humanized CD22 transgenic mouse model for in vivo analysis of anti‐CD22‐based immunotherapy

European Journal of Immunology

2020/11

Lars Nitschke
Lars Nitschke

H-Index: 26

P03. 20 A murine, myc-driven lymphoma model expressing human CD22 enables testing of targeted therapies and their effects on tumor immune microenvironment

2020/10/1

See List of Professors in Lars Nitschke University(Friedrich-Alexander-Universität Erlangen-Nürnberg)