L. David Sibley
Washington University in St. Louis
H-index: 121
North America-United States
Top articles of L. David Sibley
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Bicyclic pyrrolidine inhibitors of Toxoplasma gondii phenylalanine t-RNA synthetase with antiparasitic potency in vitro and brain exposure | bioRxiv | Chloe C Ence Taher Uddin Julien Borrel Payal Mittal Han Xie | 2024 |
Antigens for detecting toxoplasma infection by monitoring cellular immunity | 2022/8/25 | ||
Constitutive upregulation of transcription factors underlies permissive bradyzoite differentiation in a natural isolate of Toxoplasma gondii. | bioRxiv | Jing Xia Yong Fu Wanyi Huang L David Sibley | 2024 |
SKSR1 identified as key virulence factor in Cryptosporidium by genetic crossing | Lihua Xiao Wei He Lianbei Sun Tianyi Hou Zuiwei Yang | 2024/3/1 | |
Variant Surface Protein GP60 Contributes to Host Infectivity of Cryptosporidium parvum | bioRxiv | Muxiao Li Fuxian Yang Tianyi Hou Xiaoqing Gong Na Li | 2024 |
Susceptibility of Toxoplasma gondii to autophagy in human cells relies on multiple interacting parasite loci | Mbio | Nicholas Rinkenberger Alex Rosenberg Joshua B Radke Jaya Bhushan Tadakimi Tomita | 2024/1/16 |
Mendelian segregation and high recombination rates facilitate genetic analyses in Cryptosporidium parvum | bioRxiv | Abigail Kimball Lisa Funkhouser-Jones Wanyi Huang Rui Xu William H Witola | 2024 |
Multiple pathways for glucose phosphate transport and utilization support growth of Cryptosporidium parvum | Nature communications | Rui Xu Wandy L Beatty Valentin Greigert William H Witola L David Sibley | 2024/1/9 |
Genome-wide and targeted CRISPR screens identify RNF213 as a mediator of interferon gamma–dependent pathogen restriction in human cells | Proceedings of the National Academy of Sciences | Sumit K Matta Hinissan P Kohio Pallavi Chandra Adam Brown John G Doench | 2024/1/2 |
Long-term monolayer cultivation captures homeostatic and regenerative features of human colonic epithelial cells | bioRxiv | Satoru Fujii Yi Wang Shanshan Meng Ryan J Musich Scott T Espenschied | 2024 |
Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus | Gut microbes | Valentin Greigert Iti Saraav Juhee Son Yinxing Zhu Denise Dayao | 2024/12/31 |
A Combination of Four Nuclear Targeted Effectors Protects Toxoplasma Against Interferon Gamma Driven Human Host Cell Death During Acute Infection. | bioRxiv | Brittany Henry L David Sibley Alex Rosenberg | 2023 |
Autophagy gene-dependent intracellular immunity triggered by interferon-γ | Mbio | Michael R McAllaster Jaya Bhushan Dale R Balce Anthony Orvedahl Arnold Park | 2023/12/19 |
Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth | Cell reports | Lisa J Funkhouser-Jones Rui Xu Georgia Wilke Yong Fu Lawrence A Schriefer | 2023/7/25 |
Dendritic Cells and Cryptosporidium: From Recognition to Restriction | Iti Saraav L David Sibley | 2023/4/18 | |
Apical Secretory Glycoprotein Complex Contributes to Cell Attachment and Entry by Cryptosporidium parvum | Mbio | Marianna E Akey Rui Xu Soumya Ravindran Lisa Funkhouser-Jones L David Sibley | 2023/2/28 |
The Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments | Nature communications | Wenyan Wan Hui Dong De-Hua Lai Jiong Yang Kai He | 2023/2/22 |
Treatment of infections of toxoplasma gondii and closely related parasites | 2022/2/3 | ||
Immunologically active fragments of toxoplasma gondii | 2022/9/15 | ||
Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase | Nature communications | Joshua B Radke Bruno Melillo Payal Mittal Manmohan Sharma Amit Sharma | 2022/1/24 |
