Kyle K. Biggar

Kyle K. Biggar

Carleton University

H-index: 32

North America-Canada

About Kyle K. Biggar

Kyle K. Biggar, With an exceptional h-index of 32 and a recent h-index of 22 (since 2020), a distinguished researcher at Carleton University, specializes in the field of Protein biochemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

In vitro modulation of mTOR and mGlur5 influence α-synuclein accumulation

Machine learning-based exploration of enzyme-substrate networks: SET8-mediated methyllysine and its changing impact within cancer proteomes

Unraveling the battle for lysine: A review of the competition among post-translational modifications

Placental remote control of fetal metabolism: trophoblast mTOR signaling regulates liver IGFBP-1 phosphorylation and IGF-1 bioavailability

Protein Demethylases: The Characterization and Current Focus on the Development of Targeted Therapeutics

Characterization of KDM5 lysine demethylase family substrate preference and identification of novel substrates

Peptide-derived therapeutics targeting set8 for the treatment of cancer

A peptide array pipeline for the development of Spike-ACE2 interaction inhibitors

Kyle K. Biggar Information

University

Position

___

Citations(all)

3419

Citations(since 2020)

1973

Cited By

2334

hIndex(all)

32

hIndex(since 2020)

22

i10Index(all)

61

i10Index(since 2020)

54

Email

University Profile Page

Carleton University

Google Scholar

View Google Scholar Profile

Kyle K. Biggar Skills & Research Interests

Protein biochemistry

Top articles of Kyle K. Biggar

Title

Journal

Author(s)

Publication Date

In vitro modulation of mTOR and mGlur5 influence α-synuclein accumulation

Molecular Brain

Viktoria Xing

Kyle Biggar

Stephen SG Ferguson

Shawn Hayley

2024/2/15

Machine learning-based exploration of enzyme-substrate networks: SET8-mediated methyllysine and its changing impact within cancer proteomes

Kyle Biggar

Nashira Ridgeway

Anand Chopra

Valentina Lukinovic

Michal Feldman

...

2024/2/27

Unraveling the battle for lysine: A review of the competition among post-translational modifications

Ali H Shukri

Valentina Lukinović

François Charih

Kyle K Biggar

2023/9/24

Placental remote control of fetal metabolism: trophoblast mTOR signaling regulates liver IGFBP-1 phosphorylation and IGF-1 bioavailability

International Journal of Molecular Sciences

Fredrick J Rosario

Anand Chopra

Kyle Biggar

Theresa L Powell

Madhulika B Gupta

...

2023/4/14

Protein Demethylases: The Characterization and Current Focus on the Development of Targeted Therapeutics

Nashira H Ridgeway

Mullen Boulter

Matt Hoekstra

Kyle K Biggar

2023

Characterization of KDM5 lysine demethylase family substrate preference and identification of novel substrates

The Journal of Biochemistry

Matthew Hoekstra

Nashira H Ridgeway

Kyle K Biggar

2023/1

Peptide-derived therapeutics targeting set8 for the treatment of cancer

2022/6/16

A peptide array pipeline for the development of Spike-ACE2 interaction inhibitors

Peptides

Anand Chopra

Ali H Shukri

Hemanta Adhikary

Valentina Lukinović

Matthew Hoekstra

...

2022/10/21

Peptide-derived therapeutics targeting kdm5c for the treatment of cancer

2022/6/16

PeSA 2.0: A software tool for peptide specificity analysis implementing positive and negative motifs and motif-based peptide scoring

Computational Biology and Chemistry

Emine Topcu

Nashira H Ridgeway

Kyle K Biggar

2022/12/1

Assessing sequence-based protein–protein interaction predictors for use in therapeutic peptide engineering

Scientific Reports

François Charih

Kyle K Biggar

James R Green

2022/6/10

TWIST1 methylation by SETD6 selectively antagonizes LINC-PINT expression in glioma

Nucleic acids research

Lee Admoni-Elisha

Tzofit Elbaz

Anand Chopra

Guy Shapira

Mark T Bedford

...

2022/7/8

Insights into a cancer-target demethylase: substrate prediction through systematic specificity analysis for KDM3A

Biomolecules

Anand Chopra

William G Willmore

Kyle K Biggar

2022/4/27

Increased Colocalization and Interaction Between Decidual Protein Kinase A and Insulin-like Growth Factor–Binding Protein-1 in Intrauterine Growth Restriction

Journal of Histochemistry & Cytochemistry

Madhulika B Gupta

Kyle K Biggar

Cun Li

Peter W Nathanielsz

Thomas Jansson

2022/7

Evaluation of Jumonji C lysine demethylase substrate preference to guide identification of in vitro substrates

STAR protocols

Matthew Hoekstra

Anand Chopra

William G Willmore

Kyle K Biggar

2022/6/17

Assessing the in vitro Binding Affinity of Protein–RNA Interactions Using an RNA Pull-down Technique

Bio-protocol

Anand Chopra

Feras Balbous

Kyle K Biggar

2022/12/5

IGFBP-1 hyperphosphorylation in response to nutrient deprivation is mediated by activation of protein kinase Cα (PKCα)

Molecular and cellular endocrinology

Allan W Chen

Kyle Biggar

Karen Nygard

Sahil Singal

Tiffany Zhao

...

2021/10/1

Deconvoluting complex protein interaction networks through reductionist strategies in peptide biochemistry: Modern approaches and research questions

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Valentina Lukinović

Kyle K Biggar

2021/10/1

Mechanistic target of rapamycin Complex 1 signaling links hypoxia to increased IGFBP-1 phosphorylation in primary human decidualized endometrial stromal cells

Biomolecules

Pinki Nandi

Chloe E Jang

Kyle Biggar

Chidambra D Halari

Thomas Jansson

...

2021/9/18

Mechanisms linking hypoxia to phosphorylation of insulin-like growth factor binding protein-1 in baboon fetuses with intrauterine growth restriction and in cell culture

FASEB journal: official publication of the Federation of American Societies for Experimental Biology

Jenica Kakadia

Kyle Biggar

Bhawani Jain

Allan W Chen

Karen Nygard

...

2021/9

See List of Professors in Kyle K. Biggar University(Carleton University)

Co-Authors

H-index: 97
Kenneth B. Storey

Kenneth B. Storey

Carleton University

H-index: 54
Shawn Shun-Cheng Li

Shawn Shun-Cheng Li

Western University

H-index: 25
James R Green

James R Green

Carleton University

H-index: 24
Katrina J Sullivan

Katrina J Sullivan

Ottawa University

academic-engine