Judy Hirst
University of Cambridge
H-index: 63
Europe-United Kingdom
Top articles of Judy Hirst
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4−/− mouse | The EMBO Journal | Zhan Yin Ahmed-Noor A Agip Hannah R Bridges Judy Hirst | 2024/1/16 |
Tamoxifen reduces mitochondrial respiration, oncogenic signaling and mutant allele burden in a myeloproliferative neoplasm subset | Zijian Fang Giuditta Fattori Thomas McKerrell Rebecca Boucher Aimee Jackson | 2023/3/30 | |
Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes | Cell Metabolism | Dusanka Milenkovic Jelena Misic Johannes F Hevler Thibaut Molinié Injae Chung | 2023/10/3 |
Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides | Science | Hannah R Bridges James N Blaza Zhan Yin Injae Chung Michael N Pollak | 2023/1/27 |
Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I | Science Advances | Daniel N Grba Injae Chung Hannah R Bridges Ahmed-Noor A Agip Judy Hirst | 2023/8/2 |
Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster | Elife | Ahmed-Noor A Agip Injae Chung Alvaro Sanchez-Martinez Alexander J Whitworth Judy Hirst | 2023/1/9 |
The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors | Biology Direct | Rachel E Hardy Injae Chung Yizhou Yu Samantha HY Loh Nobuhiro Morone | 2023/8/1 |
Structural basis of a regulatory switch in mammalian complex I | bioRxiv | Daniel N Grba John J Wright Zhan Yin William Fisher Judy Hirst | 2023 |
Structural insights into complex I deficiency and assembly from the disease-related ndufs4-/- mouse | bioRxiv | Zhan Yin Ahmed-Noor A Agip Hannah R Bridges Judy Hirst | 2023/7/17 |
Using light scattering to assess how phospholipid–protein interactions affect complex I functionality in liposomes | RSC Chemical Biology | Jana Eisermann John J Wright James DET Wilton-Ely Judy Hirst Maxie M Roessler | 2023 |
Mechanism of rotenone binding to respiratory complex I depends on ligand flexibility | Scientific Reports | Caroline S Pereira Murilo H Teixeira David A Russell Judy Hirst Guilherme M Arantes | 2023/4/25 |
Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis | Nature Communications | Zijian Fang Giuditta Corbizi Fattori Thomas McKerrell Rebecca H Boucher Aimee Jackson | 2023/11/25 |
Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy | Nature Communications | Injae Chung John J Wright Hannah R Bridges Bozhidar S Ivanov Olivier Biner | 2022/5/19 |
Membrane-domain mutations in respiratory complex I impede catalysis but do not uncouple proton pumping from ubiquinone reduction | PNAS nexus | Owen D Jarman Judy Hirst | 2022/11 |
Reverse electron transfer by respiratory complex I catalyzed in a modular proteoliposome system | Journal of the American Chemical Society | John J Wright Olivier Biner Injae Chung Nils Burger Hannah R Bridges | 2022/4/5 |
Cryo-EM structures of minimal supercomplexes from alphaproteobacteria provide insights into mechanisms for efficient respiration | Biochimica et Biophysica Acta (BBA)-Bioenergetics | Yaikhomba Mutum Ahmed-Noor A Agip Tristan I Croll Tobias E Spikes Judy Hirst | 2022/9/1 |
Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I | Journal of Biological Chemistry | Daniel N Grba James N Blaza Hannah R Bridges Ahmed-Noor A Agip Zhan Yin | 2022/3/1 |
CryoEM structures of respiratory complex I as a basis for understanding its function and mechanism | Biochimica et Biophysica Acta (BBA)-Bioenergetics | Judy Hirst | 2022/9/1 |
Cryo-EM structures reveal ubiquinone-10 binding to mitochondrial complex I and conformational transitions associated with Q-site occupancy | bioRxiv | Injae Chung John J Wright Hannah R Bridges Bozhidar S Ivanov Olivier Biner | 2022/2/12 |
Elucidating the structure of Paracoccus denitrificans complex I, a model system for the mammalian enzyme, using lipid nanodiscs | Biochimica et Biophysica Acta (BBA)-Bioenergetics | Bozhidar S Ivanov Mutum Yaikhomba Hannah R Bridges Owen D Jarman Daniel N Grba | 2022/9/1 |
