Joseph J. Falke

Joseph J. Falke

University of Colorado Boulder

H-index: 65

North America-United States

About Joseph J. Falke

Joseph J. Falke, With an exceptional h-index of 65 and a recent h-index of 25 (since 2020), a distinguished researcher at University of Colorado Boulder, specializes in the field of Biophysics & Biochemistry of Membrane-Based Signaling Pathways.

His recent articles reflect a diverse array of research interests and contributions to the field:

PDK1: PKCα heterodimer association-dissociation dynamics in single-molecule diffusion tracks on a target membrane

Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements

Learning diffusion coefficients, kinetic parameters, and the number of underlying states from a multi-state diffusion process: robustness results and application to PDK1/PKC …

Single-molecule studies reveal regulatory interactions between master kinases PDK1, AKT1, and PKC

HPLC method to resolve, identify and quantify guanine nucleotides bound to recombinant ras GTPase

Single Molecule Studies and Kinase Activity Measurements Reveal Regulatory Interactions between the Master Kinases Phosphoinositide-Dependent-Kinase-1 (PDK1), Protein Kinase B …

Ras–guanine nucleotide complexes: A UV spectral deconvolution method to analyze protein concentration, nucleotide stoichiometry, and purity

PDK1 Forms Homodimers on Supported Lipid Bilayers in a PIP3 Dependent Manner

Joseph J. Falke Information

University

Position

Director of Molecular Biophysics Prof. of Chemistry & Biochemistry

Citations(all)

14864

Citations(since 2020)

2839

Cited By

13098

hIndex(all)

65

hIndex(since 2020)

25

i10Index(all)

123

i10Index(since 2020)

54

Email

University Profile Page

University of Colorado Boulder

Google Scholar

View Google Scholar Profile

Joseph J. Falke Skills & Research Interests

Biophysics & Biochemistry of Membrane-Based Signaling Pathways

Top articles of Joseph J. Falke

Title

Journal

Author(s)

Publication Date

PDK1: PKCα heterodimer association-dissociation dynamics in single-molecule diffusion tracks on a target membrane

Biophysical Journal

Moshe T Gordon

Brian P Ziemba

Joseph J Falke

2023/6/6

Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements

Analytical biochemistry

Ian R Fleming

Jonathan P Hannan

George Hayden Swisher

Corey D Tesdahl

Justin G Martyr

...

2023/2/15

Learning diffusion coefficients, kinetic parameters, and the number of underlying states from a multi-state diffusion process: robustness results and application to PDK1/PKC …

arXiv preprint arXiv:2206.07999

Lewis R Baker

Moshe T Gordon

Brian P Ziemba

Victoria Gershuny

Joseph J Falke

...

2022/6/16

Single-molecule studies reveal regulatory interactions between master kinases PDK1, AKT1, and PKC

Biophysical Journal

Moshe T Gordon

Brian P Ziemba

Joseph J Falke

2021/12/21

HPLC method to resolve, identify and quantify guanine nucleotides bound to recombinant ras GTPase

Analytical Biochemistry

Jonathan P Hannan

G Hayden Swisher

Justin G Martyr

Nicholas J Cordaro

Annette H Erbse

...

2021/8/22

Single Molecule Studies and Kinase Activity Measurements Reveal Regulatory Interactions between the Master Kinases Phosphoinositide-Dependent-Kinase-1 (PDK1), Protein Kinase B …

bioRxiv

Moshe T Gordon

Brian P Ziemba

Joseph J Falke

2021/6/25

Ras–guanine nucleotide complexes: A UV spectral deconvolution method to analyze protein concentration, nucleotide stoichiometry, and purity

Analytical Biochemistry

G Hayden Swisher

Jonathan P Hannan

Nicholas J Cordaro

Annette H Erbse

Joseph J Falke

2021/4/1

PDK1 Forms Homodimers on Supported Lipid Bilayers in a PIP3 Dependent Manner

Biophysical Journal

Moshe T Gordon

Joseph J Falke

2021/2/12

The G-protein Rab5A activates VPS34 complex II, a class III PI3K, by a dual regulatory mechanism

Biophysical Journal

Thomas C Buckles

Yohei Ohashi

Shirley Tremel

Stephen H McLaughlin

Els Pardon

...

2020/12/1

Rapid exposure of macrophages to drugs resolves four classes of effects on the leading edge sensory pseudopod: Non-perturbing, adaptive, disruptive, and activating

Plos one

Thomas C Buckles

Brian P Ziemba

Danijel Djukovic

Joseph J Falke

2020/5/29

Regulatory Mechanisms of Ca2+, Receptor, Ras, and Lipid Signals that Control Actin Polymerization During Cell Migration

Biophysical Journal

Joseph J Falke

Brian P Ziemba

Thomas C Buckles

Roger L Williams

Glenn Masson

2020/2/7

Direct Detection and Characterization of a Phosphoinositide Dependent Kinase-1 (PDK1) Homodimer on a Target Membrane Surface Via Single Molecule Fluorescence

Biophysical Journal

Moshe T Gordon

Joseph J Falke

2020/2/7

Binding of Ras to PI3K: Measuring Binding Affinity, and the Effects of Disease-Linked H-Ras Mutations on Affinity

Biophysical Journal

G Hayden Swisher

Nicholas J Cordaro

Justin G Martyr

Annette H Erbse

Johnathon H Hannan

...

2020/2/7

See List of Professors in Joseph J. Falke University(University of Colorado Boulder)