John M Denu

John M Denu

University of Wisconsin-Madison

H-index: 87

North America-United States

About John M Denu

John M Denu, With an exceptional h-index of 87 and a recent h-index of 49 (since 2020), a distinguished researcher at University of Wisconsin-Madison, specializes in the field of Epigenetics, Biochemistry, Enzymology, Aging, Metabolism.

His recent articles reflect a diverse array of research interests and contributions to the field:

PD35-07 IDENTIFYING AND TARGETING UPREGULATED HISTONE MODIFYING ENZYMES INVOLVED IN PROSTATE CANCER CELL SURVIVAL AFTER ANDROGEN DEPRIVATION THERAPY

Protein restriction slows the development and progression of Alzheimer's disease in mice

Dietary restriction of individual amino acids stimulates unique molecular responses in mouse liver

Abstract B051: Alterations in SIRT2-H3K18Ac identify increased P300 activity in circulating tumor cells from patients with CRPC

Nucleic acid sequence contributes to remodeler-mediated targeting of histone H2A. Z

Abstract A060: Genetic alterations induce distinct histone post-translational modifications during the transition to castration-resistant prostate cancer

Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide‐Activated Sirtuin 7

Development of a multiplex assay to assess activated p300/CBP in circulating prostate tumor cells

John M Denu Information

University

Position

Wisconsin Institute for Discovery Professor of Biomolecular Chemistry

Citations(all)

33371

Citations(since 2020)

10053

Cited By

27262

hIndex(all)

87

hIndex(since 2020)

49

i10Index(all)

180

i10Index(since 2020)

144

Email

University Profile Page

University of Wisconsin-Madison

Google Scholar

View Google Scholar Profile

John M Denu Skills & Research Interests

Epigenetics

Biochemistry

Enzymology

Aging

Metabolism

Top articles of John M Denu

Title

Journal

Author(s)

Publication Date

PD35-07 IDENTIFYING AND TARGETING UPREGULATED HISTONE MODIFYING ENZYMES INVOLVED IN PROSTATE CANCER CELL SURVIVAL AFTER ANDROGEN DEPRIVATION THERAPY

The Journal of Urology

Tanaya Purohit

Emily Schmitt

Marcelo Bigarella

Kayla Bahr

Sean Sardeson

...

2024/5

Protein restriction slows the development and progression of Alzheimer's disease in mice

Research Square

Reji Babygirija

Michelle M Sonsalla

Jessica H Han

Isabella James

Cara L Green

...

2023/9/12

Dietary restriction of individual amino acids stimulates unique molecular responses in mouse liver

bioRxiv

Spencer Haws

Yang Liu

Cara Green

Reji Babygirija

Eric Armstrong

...

2023

Abstract B051: Alterations in SIRT2-H3K18Ac identify increased P300 activity in circulating tumor cells from patients with CRPC

Cancer Research

Mikolaj Filon

Bing Yang

Jennifer Schehr

Anupama Singh

Marcelo Bigarella

...

2023/6/2

Nucleic acid sequence contributes to remodeler-mediated targeting of histone H2A. Z

bioRxiv

Cynthia Converso

Leonidas Pierrakeas

Lirong Chan

Shalvi Chowdhury

Vyacheslav I Kuznetsov

...

2023

Abstract A060: Genetic alterations induce distinct histone post-translational modifications during the transition to castration-resistant prostate cancer

Cancer Research

Tanaya A Purohit

Joseph Gawdzik

Bing Yang

Eric A Armstrong

Peter W Lewis

...

2023/6/2

Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide‐Activated Sirtuin 7

Angewandte Chemie International Edition

Julie E Bolding

Alexander L Nielsen

Iben Jensen

Tobias N Hansen

Line A Ryberg

...

2023/10/24

Development of a multiplex assay to assess activated p300/CBP in circulating prostate tumor cells

Oncotarget

Mikolaj Filon

Bing Yang

Tanaya A Purohit

Jennifer Schehr

Anupama Singh

...

2023

Development and initial clinical testing of a multiplex assay evaluating histone modifier p300 acetylation in prostate cancer circulating tumor cells.

David Frazier Jarrard

Mikolaj Filon

Bing Yang

Jennifer L Schehr

Anupama Singh

...

2023/6/1

DOT1L is a barrier to histone acetylation during reprogramming to pluripotency

Science Advances

Coral K Wille

Xiaoya Zhang

Spencer A Haws

John M Denu

Rupa Sridharan

2023/11/17

Overexpression of the citrate transporters SLC13A5 and SLC25A1 leads to different phenotypes in the mouse

Journal of Biological Chemistry

Gonzalo Fernandez-Fuente

Katherine Overmyer

Alexis Lawton

Ildiko Kasza

Patricia Gallego-Muoz

...

2023/1/1

Sirtuin 6 protein deacylase (sirt6) activators

2023/3/2

The citrate transporters SLC13A5 and SLC25A1 elicit different metabolic responses and phenotypes in the mouse

Communications Biology

Gonzalo Fernandez-Fuente

Katherine A Overmyer

Alexis J Lawton

Ildiko Kasza

Samantha L Shapiro

...

2023/9/9

Acss2 Deletion Reveals Functional Versatility via Tissue-Specific Roles in Transcriptional Regulation

International Journal of Molecular Sciences

Narayanan Puthillathu Vasudevan

Dharmendra K Soni

John R Moffett

Jishnu KS Krishnan

Abhilash P Appu

...

2023/2/12

Intrinsic catalytic properties of histone H3 lysine-9 methyltransferases preserve monomethylation levels under low S-adenosylmethionine

Journal of Biological Chemistry

Spencer A Haws

Lillian J Miller

Diego Rojas La Luz

Vyacheslav I Kuznetsov

Raymond C Trievel

...

2023/7/1

Antagonistic H3K79me-H3K9ac crosstalk determines elongation at housekeeping genes to promote pluripotency

Biorxiv

Coral K Wille

Xiaoya Zhang

Spencer A Haws

John M Denu

Rupa Sridharan

2022/9/27

Sirt6 regulates lifespan in Drosophila melanogaster

Proceedings of the National Academy of Sciences

Jackson R Taylor

Jason G Wood

Evan Mizerak

Samuel Hinthorn

Julianna Liu

...

2022/2/1

Potent Activation of NAD+-Dependent Deacetylase Sirt7 by Nucleosome Binding

ACS chemical biology

Vyacheslav I Kuznetsov

Wallace H Liu

Mark A Klein

John M Denu

2022/8/8

SLC13A5/sodium-citrate co-transporter overexpression causes disrupted white matter integrity and an autistic-like phenotype

Brain Communications

Michael J Rigby

Nicola Salvatore Orefice

Alexis J Lawton

Min Ma

Samantha L Shapiro

...

2022/2/1

Histone Acid Extraction and High Throughput Mass Spectrometry to Profile Histone Modifications in Arabidopsis thaliana

Current Protocols

Ray Scheid

James A. Dowell

Dean Sanders

Jianjun Jiang

John M. Denu

...

2022/8/22

See List of Professors in John M Denu University(University of Wisconsin-Madison)