John Essigmann

John Essigmann

Massachusetts Institute of Technology

H-index: 76

North America-United States

About John Essigmann

John Essigmann, With an exceptional h-index of 76 and a recent h-index of 33 (since 2020), a distinguished researcher at Massachusetts Institute of Technology, specializes in the field of Toxicology, cancer research, biochemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

Stable Interstrand Cross-Links Generated from the Repair of 1,N6-Ethenoadenine in DNA by α-Ketoglutarate/Fe(II)-Dependent Dioxygenase ALKBH2

5-Chloro-2′-deoxycytidine Induces a Distinctive High-Resolution Mutational Spectrum of Transition Mutations In Vivo

A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress

Interaction of N-nitrosamines with binuclear copper complexes for luminescent detection

Molecular origins of mutational spectra produced by the environmental carcinogen N-nitrosodimethylamine and SN1 chemotherapeutic agents

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Establishing linkages among DNA damage, mutagenesis, and genetic diseases

7,8-Dihydro-8-oxo-1,N6-ethenoadenine: an exclusively Hoogsteen-paired thymine mimic in DNA that induces A→T transversions in Escherichia coli

John Essigmann Information

University

Position

___

Citations(all)

21952

Citations(since 2020)

3681

Cited By

19736

hIndex(all)

76

hIndex(since 2020)

33

i10Index(all)

178

i10Index(since 2020)

84

Email

University Profile Page

Massachusetts Institute of Technology

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John Essigmann Skills & Research Interests

Toxicology

cancer research

biochemistry

Top articles of John Essigmann

Title

Journal

Author(s)

Publication Date

Stable Interstrand Cross-Links Generated from the Repair of 1,N6-Ethenoadenine in DNA by α-Ketoglutarate/Fe(II)-Dependent Dioxygenase ALKBH2

Journal of the American Chemical Society

Jie Wang

Nathania A Takyi

Yun-Chung Hsiao

Qi Tang

Yi-Tzai Chen

...

2024/4/4

5-Chloro-2′-deoxycytidine Induces a Distinctive High-Resolution Mutational Spectrum of Transition Mutations In Vivo

Chemical Research in Toxicology

Marisa Chancharoen

Zhiyu Yang

Esha D Dalvie

Nina Gubina

Mathuros Ruchirawat

...

2024/2/23

A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress

Proceedings of the National Academy of Sciences

Bogdan I Fedeles

Rishi Bhardwaj

Yasunobu Ishikawa

Sakunchai Khumsubdee

Matteus Krappitz

...

2024/1/23

Interaction of N-nitrosamines with binuclear copper complexes for luminescent detection

Dalton Transactions

Haosheng Feng

Shao-Xiong Lennon Luo

Robert G Croy

John M Essigmann

Timothy M Swager

2023

Molecular origins of mutational spectra produced by the environmental carcinogen N-nitrosodimethylamine and SN1 chemotherapeutic agents

NAR cancer

Amanda L Armijo

Pennapa Thongararm

Bogdan I Fedeles

Judy Yau

Jennifer E Kay

...

2023/6/1

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Perspective

Sunkyung Kim

Jing Chen

Feiya Ou

Tian-Tian Liu

Suin Jo

...

2024/3/4

Establishing linkages among DNA damage, mutagenesis, and genetic diseases

Ashis K Basu

John M Essigmann

2022/7/26

7,8-Dihydro-8-oxo-1,N6-ethenoadenine: an exclusively Hoogsteen-paired thymine mimic in DNA that induces A→T transversions in Escherichia coli

Nucleic acids research

Andrey V Aralov

Nina Gubina

Cristina Cabrero

Vladimir B Tsvetkov

Anton V Turaev

...

2022/4/8

Metallocalix[4]arene Polymers for Gravimetric Detection of N-Nitrosodialkylamines

Journal of the American Chemical Society

Ru-Qiang Lu

Weize Yuan

Robert G Croy

John M Essigmann

Timothy M Swager

2021/11/18

Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

Cell reports

Jennifer E Kay

Joshua J Corrigan

Amanda L Armijo

Ilana S Nazari

Ishwar N Kohale

...

2021/3/16

Andrographolide, an antioxidant, counteracts paraquat-induced mutagenesis in mammalian cells

Preechaya Tajai

Tawit Suriyo

Nuchanart Rangkadilok

Bogdan I Fedeles

John M Essigmann

...

2021

Mutational spectra provide insight into the mechanisms bridging DNA damage to genetic disease

BI Fedeles

JM Essigmann

2020/11/11

Abstract IA04: Mutational spectra of environmental carcinogens as biomarkers for early detection of cancer

Cancer Prevention Research

Bogdan I Fedeles

Supawadee Chawanthayatham

Amanda L Armijo

Robert G Croy

John M Essigmann

2020/7/1

See List of Professors in John Essigmann University(Massachusetts Institute of Technology)