John Charles Chaput

John Charles Chaput

University of California, Irvine

H-index: 37

North America-United States

About John Charles Chaput

John Charles Chaput, With an exceptional h-index of 37 and a recent h-index of 31 (since 2020), a distinguished researcher at University of California, Irvine, specializes in the field of chemical biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Increasing the functional density of threose nucleic acid

Alternative Synthesis of α-l-Threofuranosyl Guanosine 3′-triphosphate

Compositions and methods for synthesis of phosphorylated molecules

Metabolic adjustments in response to ATP spilling by the small DX protein in a Streptomyces strain

Highly Parallelized Screening of Functionally Enhanced XNA Aptamers in Uniform Hydrogel Particles

Screening artificial nucleic acids by particle display

Engineering TNA polymerases through iterative cycles of directed evolution.

Functionally Enhanced XNA Aptamers Discovered by Parallelized Library Screening

John Charles Chaput Information

University

Position

Profess

Citations(all)

6219

Citations(since 2020)

3627

Cited By

3959

hIndex(all)

37

hIndex(since 2020)

31

i10Index(all)

95

i10Index(since 2020)

69

Email

University Profile Page

University of California, Irvine

Google Scholar

View Google Scholar Profile

John Charles Chaput Skills & Research Interests

chemical biology

Top articles of John Charles Chaput

Title

Journal

Author(s)

Publication Date

Increasing the functional density of threose nucleic acid

RSC Chemical Biology

Biju Majumdar

Daisy Sarma

Yutong Yu

Adriana Lozoya-Colinas

John C Chaput

2024

Alternative Synthesis of α-l-Threofuranosyl Guanosine 3′-triphosphate

Synlett

Daisy Sarma

Biju Majumdar

John C Chaput

2024/4

Compositions and methods for synthesis of phosphorylated molecules

2024/1/2

Metabolic adjustments in response to ATP spilling by the small DX protein in a Streptomyces strain

Frontiers in Cell and Developmental Biology

Cécile Apel

Marceau Levasseur

Clara Lejeune

Shaleen B Korch

Florence Guérard

...

2023/3/8

Highly Parallelized Screening of Functionally Enhanced XNA Aptamers in Uniform Hydrogel Particles

ACS Synthetic Biology

EJ Yik

E Medina

BM Paegel

John C Chaput

2023/7/6

Screening artificial nucleic acids by particle display

2023/2/28

Engineering TNA polymerases through iterative cycles of directed evolution.

Methods in Enzymology

Eric J Yik

Victoria A Maola

John C Chaput

2023/5/10

Functionally Enhanced XNA Aptamers Discovered by Parallelized Library Screening

Journal of the American Chemical Society

Adriana Lozoya-Colinas

Yutong Yu

John C Chaput

2023/11/14

Chemical evolution of an autonomous DNAzyme with allele-specific gene silencing activity

Nature communications

Kim Nguyen

Turnee N Malik

John C Chaput

2023/4/27

Parameterizing the Binding Properties of XNA Aptamers Isolated from a Low Stringency Selection

Biochemistry

Nandini Kundu

Cailen M McCloskey

Mohammad Hajjar

John C Chaput

2023/11/6

Advancing XNAzymes as Nucleic Acid Therapeutics

Yajun Wang

John C Chaput

2023/4/1

Stability and mechanism of threose nucleic acid toward acid-mediated degradation

Nucleic Acids Research

Erica M Lee

Noah A Setterholm

Mohammad Hajjar

Bhawna Barpuzary

John C Chaput

2023/10/13

Amplification-Free COVID-19 Detection by Digital Droplet REVEALR

ACS synthetic biology

Kefan Yang

John C Chaput

2023/3/22

Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small …

Journal of the American Chemical Society

Shigeo Matsuda

Saikat Bala

Jen-Yu Liao

Dhrubajyoti Datta

Atsushi Mikami

...

2023/8/28

REVEALR-based genotyping of SARS-CoV-2 variants of concern in clinical samples

Journal of the American Chemical Society

Kefan Yang

Daniel N Schuder

Arlene K Ngor

John C Chaput

2022/6/21

Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid

Nucleic acids research

Mohammad Hajjar

Nicholas Chim

Chao Liu

Piet Herdewijn

John C Chaput

2022/9/23

Reply to: On gene silencing by the X10-23 DNAzyme

Nature Chemistry

Robert C Spitale

John C Chaput

2022/8

Laser-induced confocal microscope and microfluidic device for dielectrophoretic fluorescence-activated droplet sorting

2020/11/5

Allele-specific RNA knockdown with a biologically stable and catalytically efficient XNAzyme

Journal of the American Chemical Society

Kim Nguyen

Yajun Wang

Whitney E England

John C Chaput

Robert C Spitale

2021/3/22

Modifying bioavailability of ATP and measuring metabolic response in HeLa cells

Cancer Research

Taha Muhammad

Ashley Brown

Selina Martinez

John C Chaput

Jeffrey Norris

...

2021/7/1

See List of Professors in John Charles Chaput University(University of California, Irvine)