John Bushweller
University of Virginia
H-index: 52
North America-United States
Top articles of John Bushweller
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1 | Iscience | Daniel JL Coleman Peter Keane Paulynn S Chin Luke Ames Sophie Kellaway | 2024/4/19 |
RUNX2 inhibition alters PAX3:: FOXO1 driven fusion-positive rhabdomyosarcoma cell state and growth | Cancer Research | Elizabeth A Mendes Audrey L Chambers Samantha J Weitzel Michael Deel Aanandi Munshi | 2024/3/22 |
Combination therapies for treating cancer | 2022/9/7 | ||
N-MYC regulates cell survival via eIF4G1 in inv (16) acute myeloid leukemia | Science Advances | Philomina Sona Peramangalam Sridevi Surapally Anthony J Veltri Shikan Zheng Robert Burns | 2024/2/28 |
Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth | Cell Reports | Daniel JL Coleman Peter Keane Rosario Luque-Martin Paulynn S Chin Helen Blair | 2023/12/26 |
P444: SINGLE CELL RNASEQ UNCOVERING THE ROLE OF A LEUKEMIC DRIVER GENE FUSION CBFΒ:: MYH11 IN THE LEUKEMIC–NICHE SIGNALING | HemaSphere | Polina Derevyanko Alexandra V Dolgikh Minoo Ashtiani Anja Krippner-Heidenreich Ryan Nelson | 2023/8/1 |
The intrinsically disordered proteins MLLT3 (AF9) and MLLT1 (ENL)–multimodal transcriptional switches with roles in normal hematopoiesis, MLL fusion leukemia, and kidney cancer | Ashish Kabra John Bushweller | 2022/1/15 | |
3053–DEFINING THE GENE REGULATORY NETWORKS TARGETED BY RUNX1 AND FLT3 INHIBITORS | Experimental Hematology | Peter Cockerill Salam Assi Constanze Bonifer John Bushweller Paulynn Chin | 2022/1/1 |
Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability | Nature Communications | Jason P Wray Elitza M Deltcheva Charlotta Boiers Simon Е Richardson Jyoti Bikram Chhetri | 2022/11/21 |
Small-molecule inhibitors of the mll1 cxxc domain, an epigenetic reader of DNA methylation | ACS Medicinal Chemistry Letters | Hanuman P Kalmode Izabella Podsiadly Ashish Kabra Adam Boulton Prabhakar Reddy | 2022/7/7 |
KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancer | Science Advances | Kee-Beom Kim Ashish Kabra Dong-Wook Kim Yongming Xue Yuanjian Huang | 2022/2/16 |
Unique role and vulnerability of EP300 KIX domain in small-cell lung cancer | bioRxiv | Kee-Beom Kim Ashish Kabra Dong-Wook Kim Yongming Xue Pei-Chi Hou | 2021/6/3 |
TNF‐α signaling regulates RUNX1 function in endothelial cells | The FASEB Journal | Hannah AB Whitmore Dhanesh Amarnani Michael O'Hare Santiago Delgado‐Tirado Lucia Gonzalez‐Buendia | 2021/2 |
The epigenetic eraser LSD1 lies at the apex of a reversible erythroid to myeloid cell fate decision | bioRxiv | Lei Yu Greggory Myers Chia-Jui Ku Emily Schneider Yu Wang | 2021/1/14 |
The CBFβ-SMMHC/NRP1 Axis Regulates FLT3 and TGF-Beta Pathways in Inv (16) Acute Myeloid Leukemia | Blood | Mahesh Hegde Mohd Hafiz Ahmad Rui Li Anneliese Carrascoso Roger Mulet-Lazaro | 2021/11/23 |
An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation | Blood, The Journal of the American Society of Hematology | Lei Yu Greggory Myers Chia-Jui Ku Emily Schneider Yu Wang | 2021/11/4 |
Targeting runt-related transcription factor 1 prevents pulmonary fibrosis and reduces expression of severe acute respiratory syndrome coronavirus 2 host mediators | The American Journal of Pathology | Michael O'Hare Dhanesh Amarnani Hannah AB Whitmore Miranda An Claudia Marino | 2021/7/1 |
Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking | Oncotarget | Joshua T Rose Eliana Moskovitz Joseph R Boyd Jonathan A Gordon Nicole A Bouffard | 2020/6/6 |
RUNX transcription factor mediated control of breast cancer stem cells | Journal of cellular physiology | Andrew J Fritz Deli Hong Joseph Boyd Jason Kost Kristiaan H Finstaad | 2020/10 |
RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cells | Journal of cellular physiology | Andrew J Fritz Deli Hong Joseph Boyd Jason Kost Kristiaan H Finstaad | 2020/10 |
