Jianhan Chen
University of Massachusetts Amherst
H-index: 38
North America-United States
Top articles of Jianhan Chen
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Backbone interactions and secondary structures in phase separation of disordered proteins | Shanlong Li Yumeng Zhang Jianhan Chen | 2024/2/13 | |
Re-balancing replica exchange with solute tempering for sampling dynamic protein conformations | Journal of Chemical Theory and Computation | Yumeng Zhang Xiaorong Liu Jianhan Chen | 2023/2/15 |
Toward accurate simulation of coupling between protein secondary structure and phase separation | Journal of the American Chemical Society | Yumeng Zhang Shanlong Li Xiping Gong Jianhan Chen | 2023/12/19 |
Hydrophobic gating in bundle-crossing ion channels: a case study of TRPV4 | Communications Biology | Jian Huang Jianhan Chen | 2023/2/10 |
Incorporating physics to overcome data scarcity in predictive modeling of protein function: A case study of BK channels | PLOS Computational Biology | Erik Nordquist Guohui Zhang Shrishti Barethiya Nathan Ji Kelli M White | 2023/9/15 |
Coupled binding and folding of disordered SPIN N-terminal region in myeloperoxidase inhibition | Frontiers in Molecular Biosciences | Yumeng Zhang Xiaorong Liu Jianhan Chen | 2023/2/9 |
Accurate Simulation of Coupling between Protein Secondary Structure and Liquid-Liquid Phase Separation | bioRxiv | Yumeng Zhang Shanlong Li Xiping Gong Jianhan Chen | 2023/8/23 |
Machine learning generation of dynamic protein conformational ensembles | Li-E Zheng Shrishti Barethiya Erik Nordquist Jianhan Chen | 2023/5/12 | |
Inner pore hydration free energy controls the activation of big potassium channels | Biophysical Journal | Erik B Nordquist Zhiguang Jia Jianhan Chen | 2023/4/4 |
Computationally-aided modeling of Hsp70–client interactions: past, present, and future | Erik B Nordquist Eugenia M Clerico Jianhan Chen Lila M Gierasch | 2022/8/30 | |
Using metadynamics to explore the free energy of dewetting in biologically relevant nanopores | The Journal of Physical Chemistry B | Erik B Nordquist Samantha A Schultz Jianhan Chen | 2022/8/23 |
Intrinsically disordered N-terminal domain (NTD) of p53 interacts with mitochondrial PTP regulator Cyclophilin D | Journal of Molecular Biology | Jing Zhao Xinyue Liu Alan Blayney Yumeng Zhang Lauren Gandy | 2022/5/15 |
An allosteric modulator activates BK channels by perturbing coupling between Ca2+ binding and pore opening | Nature communications | Guohui Zhang Xianjin Xu Zhiguang Jia Yanyan Geng Hongwu Liang | 2022/11/9 |
Activation of TMEM16F by inner gate charged mutations and possible lipid/ion permeation mechanisms | Biophysical Journal | Zhiguang Jia Jian Huang Jianhan Chen | 2022/9/20 |
Toward accurate coarse-grained simulations of disordered proteins and their dynamic interactions | Journal of chemical information and modeling | Yumeng Zhang Xiaorong Liu Jianhan Chen | 2022/9/9 |
Cancer-associated mutations perturb the disordered ensemble and interactions of the intrinsically disordered p53 transactivation domain | Journal of molecular biology | Lynn G Schrag Xiaorong Liu Indhujah Thevarajan Om Prakash Michal Zolkiewski | 2021/7/23 |
Specific PIP2 binding promotes calcium activation of TMEM16A chloride channels | Communications Biology | Zhiguang Jia Jianhan Chen | 2021/2/26 |
Accelerating atomistic simulations of proteins using multiscale enhanced sampling with independent tempering | Journal of computational chemistry | Xiaorong Liu Xiping Gong Jianhan Chen | 2021/2/15 |
EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction | Nature communications | Jing Zhao Alan Blayney Xiaorong Liu Lauren Gandy Weihua Jin | 2021/2/12 |
Physics-based modeling provides predictive understanding of selectively promiscuous substrate binding by Hsp70 chaperones | PLOS Computational Biology | Erik B Nordquist Charles A English Eugenia M Clerico Woody Sherman Lila M Gierasch | 2021/11/4 |
