Jianbin Ruan

Jianbin Ruan

University of Connecticut

H-index: 25

North America-United States

About Jianbin Ruan

Jianbin Ruan, With an exceptional h-index of 25 and a recent h-index of 23 (since 2020), a distinguished researcher at University of Connecticut, specializes in the field of Structural Biology, Immunology.

His recent articles reflect a diverse array of research interests and contributions to the field:

A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis

NLRP inflammasomes in health and disease

Regulating GSDMB pore formation: to ignite or inhibit?

An ancient defense mechanism: Conservation of gasdermin-mediated pyroptosis

Structural basis for GSDMB pore formation and its targeting by IpaH7. 8

Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors

Mechanistic insights into gasdermin pore formation and regulation in pyroptosis

Gasdermin D pore structure reveals preferential release of mature interleukin-1

Jianbin Ruan Information

University

Position

University of Connecticut Health Center

Citations(all)

8175

Citations(since 2020)

6609

Cited By

3718

hIndex(all)

25

hIndex(since 2020)

23

i10Index(all)

29

i10Index(since 2020)

28

Email

University Profile Page

Google Scholar

Jianbin Ruan Skills & Research Interests

Structural Biology

Immunology

Top articles of Jianbin Ruan

A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis

Cell Reports

2024/4/23

Regulating GSDMB pore formation: to ignite or inhibit?

Cell Death & Differentiation

2023/6

Jianbin Ruan
Jianbin Ruan

H-Index: 19

An ancient defense mechanism: Conservation of gasdermin-mediated pyroptosis

Plos Biology

2023/5/4

Chengliang Wang
Chengliang Wang

H-Index: 29

Jianbin Ruan
Jianbin Ruan

H-Index: 19

Structural basis for GSDMB pore formation and its targeting by IpaH7. 8

Nature

2023/4/20

Mechanistic insights into gasdermin pore formation and regulation in pyroptosis

2022/2/28

Chengliang Wang
Chengliang Wang

H-Index: 29

Jianbin Ruan
Jianbin Ruan

H-Index: 19

Gasdermin D pore structure reveals preferential release of mature interleukin-1

Nature

2021/5/27

Intracellular immune sensing promotes inflammation via gasdermin D–driven release of a lectin alarmin

Nature immunology

2021/2

Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes

Nature communications

2021/1/8

Novel mode of filament formation in UPA-promoted CARD8 and NLRP1 Inflammasomes

bioRxiv

2020/6/27

Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS

Science immunology

2020/11/27

FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

Nature immunology

2020/7

See List of Professors in Jianbin Ruan University(University of Connecticut)

Co-Authors

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