Hidde Ploegh

Hidde Ploegh

Harvard University

H-index: 163

North America-United States

About Hidde Ploegh

Hidde Ploegh, With an exceptional h-index of 163 and a recent h-index of 75 (since 2020), a distinguished researcher at Harvard University, specializes in the field of biochemistry and immunology.

His recent articles reflect a diverse array of research interests and contributions to the field:

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

Author Correction: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

E2-type ubiquitin-conjugating enzymes probed with nanobody tools

Engineered ligands and uses thereof

Nanobody-targeted conditional antimicrobial therapeutics

MICA-specific nanobodies for diagnosis and immunotherapy of MICA+ tumors

Antagonistic nanobodies reveal mechanism of GSDMD pore formation and unexpected therapeutic potential

A large-scale volumetric correlated light and electron microscopy study localizes Alzheimer’s disease-related molecules in the hippocampus

Hidde Ploegh Information

University

Position

Senior Investigator, Program in Cellular and Molecular Medicine, Boston Children's Hospital

Citations(all)

109334

Citations(since 2020)

26936

Cited By

93003

hIndex(all)

163

hIndex(since 2020)

75

i10Index(all)

603

i10Index(since 2020)

391

Email

University Profile Page

Harvard University

Google Scholar

View Google Scholar Profile

Hidde Ploegh Skills & Research Interests

biochemistry and immunology

Top articles of Hidde Ploegh

Title

Journal

Author(s)

Publication Date

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

Nature

Yu-Hwa Huang

Chen Zhu

Yasuyuki Kondo

Ana C Anderson

Amit Gandhi

...

2016

Author Correction: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

Nature

Yu-Hwa Huang

Chen Zhu

Yasuyuki Kondo

Ana C Anderson

Amit Gandhi

...

2024/2/9

E2-type ubiquitin-conjugating enzymes probed with nanobody tools

Biophysical Journal

Pavana Suresh

Nanette Becht

Zhen-Yu Jim Sun

Novalia Pishesha

Hidde Ploegh

2024/2/8

Engineered ligands and uses thereof

2024/1/23

Nanobody-targeted conditional antimicrobial therapeutics

bioRxiv

Chayanon Ngambenjawong

Henry Ko

Novalia Pishesha

Hidde L Ploegh

Sangeeta N Bhatia

2024

MICA-specific nanobodies for diagnosis and immunotherapy of MICA+ tumors

Frontiers in Immunology

Elisha R Verhaar

Anouk Knoflook

Novalia Pishesha

Xin Liu

Willemijn JC van Keizerswaard

...

2024/3/14

Antagonistic nanobodies reveal mechanism of GSDMD pore formation and unexpected therapeutic potential

bioRxiv

Lisa DJ Schiffelers

Sabine Normann

Sophie C Binder

Elena Hagelauer

Anja Kopp

...

2023/4/21

A large-scale volumetric correlated light and electron microscopy study localizes Alzheimer’s disease-related molecules in the hippocampus

bioRxiv

Xiaomeng Han

Peter H Li

Shuohong Wang

Morgan Sanchez

Sneha Aggarwal

...

2023/10/26

18F labeling of proteins using sortases

2023/12/26

Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut

Cell Host & Microbe

Jason P Lynch

Coral González-Prieto

Analise Z Reeves

Sena Bae

Urmila Powale

...

2023/4/12

Nanobody (vhh) conjugates and uses there of

2023/7/27

Selective Targeting of Nanobody-Modified Gold Nanoparticles to Distinct Cell Types

ACS Applied Materials & Interfaces

Yoon Ho Lee

Himadri Medhi

Xin Liu

In Han Ha

Ki Tae Nam

...

2023/12/13

HYDROGEL-BASED STAMPING TECHNOLOGY FOR SOLUTION-FREE BLOOD CELL STAINING

ACS Applied Materials & Interfaces

Jae-Hyeok Choi

Lip Ket Chin

Bo Mee Woo

Younghoon Song

Min Jeong Seol

...

2021/4/19

An armed anti-immunoglobulin light chain nanobody protects mice against influenza A and B infections

Science Immunology

Xin Liu

Thomas Balligand

Claire Carpenet

Hidde L Ploegh

2023/6/23

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism

Proceedings of the National Academy of Sciences

Jin Gan

Adán Pinto-Fernández

Dennis Flierman

Jimmy JLL Akkermans

Darragh P O’Brien

...

2023/12/12

Multiplexed volumetric CLEM enabled by antibody derivatives provides new insights into the cytology of the mouse cerebellar cortex

Research Square

Xiaomeng Han

Xiaotang Lu

Peter H Li

Shuohong Wang

Richard Schalek

...

2023/5/21

ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages

bioRxiv

Timothy A Bates

Mila Trank-Greene

Xammy Nguyenla

Aidan Anastas

Sintayehu Gurmessa

...

2023/12/1

Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells

JCI insight

Suzanne E Engelen

Francesca A Ververs

Angela Markovska

B Christoffer Lagerholm

Jordan M Kraaijenhof

...

2023/5/5

Nanobody based imaging and targeting of ecm in disease and development

2023/11/2

Targeted delivery of immune-modulating vhh and vhh-fusion protein

2022/6/9

See List of Professors in Hidde Ploegh University(Harvard University)

Co-Authors

H-index: 174
Dan Littman

Dan Littman

New York University

H-index: 146
David Hafler

David Hafler

Yale University

H-index: 93
Matthew Bogyo

Matthew Bogyo

Stanford University

H-index: 46
Edda Fiebiger

Edda Fiebiger

Harvard University

H-index: 33
Eva Frickel

Eva Frickel

University of Birmingham

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