Jian Yu

Jian Yu

University of Pittsburgh

H-index: 71

North America-United States

About Jian Yu

Jian Yu, With an exceptional h-index of 71 and a recent h-index of 43 (since 2020), a distinguished researcher at University of Pittsburgh, specializes in the field of cell death, stress adaptation, colon cancer, intestinal stem cell, inflammation.

His recent articles reflect a diverse array of research interests and contributions to the field:

Inhibition of multiple CDKs potentiates colon cancer chemotherapy via p73-mediated DR5 induction

Release of Interferon-β (IFN-β) from Probiotic Limosilactobacillus reuteri-IFN-β (LR-IFN-β) Mitigates Gastrointestinal Acute Radiation Syndrome (GI-ARS) following …

UNSEG: unsupervised segmentation of cells and their nuclei in complex tissue samples

mTOR inhibition suppresses Myc-driven polyposis by inducing immunogenic cell death

Targeting Myc-driven stress addiction in colorectal cancer

Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer

Lactobacillus reuteri Releasing IL-22 (LR-IL-22) Facilitates Intestinal Radioprotection for Whole-Abdomen Irradiation (WAI) of Ovarian Cancer

tRF3008A suppresses the progression and metastasis of colorectal cancer by destabilizing FOXK1 in an AGO-dependent manner

Jian Yu Information

University

Position

Professor of Pathology and Radiation Oncology

Citations(all)

26136

Citations(since 2020)

5606

Cited By

22656

hIndex(all)

71

hIndex(since 2020)

43

i10Index(all)

135

i10Index(since 2020)

119

Email

University Profile Page

University of Pittsburgh

Google Scholar

View Google Scholar Profile

Jian Yu Skills & Research Interests

cell death

stress adaptation

colon cancer

intestinal stem cell

inflammation

Top articles of Jian Yu

Title

Journal

Author(s)

Publication Date

Inhibition of multiple CDKs potentiates colon cancer chemotherapy via p73-mediated DR5 induction

Oncogene

Jingshan Tong

Xiao Tan

Suisui Hao

Kaylee Ermine

Xinyan Lu

...

2023/3/16

Release of Interferon-β (IFN-β) from Probiotic Limosilactobacillus reuteri-IFN-β (LR-IFN-β) Mitigates Gastrointestinal Acute Radiation Syndrome (GI-ARS) following …

Cancers

Diala F Hamade

Michael W Epperly

Renee Fisher

Wen Hou

Donna Shields

...

2023/3/8

UNSEG: unsupervised segmentation of cells and their nuclei in complex tissue samples

bioRxiv

Bogdan Kochetov

Phoenix Bell

Paulo S Garcia

Akram S Shalaby

Rebecca Raphael

...

2023/11/15

mTOR inhibition suppresses Myc-driven polyposis by inducing immunogenic cell death

Oncogene

Brian J Leibowitz

Guangyi Zhao

Wenxin Xia

Yuhan Wang

Hang Ruan

...

2023/6/9

Targeting Myc-driven stress addiction in colorectal cancer

Haris Saeed

Brian J Leibowitz

Lin Zhang

Jian Yu

2023/4/20

Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer

Molecular Biomedicine

Hang Ruan

Brian J Leibowitz

Yingpeng Peng

Lin Shen

Lujia Chen

...

2022/3/21

Lactobacillus reuteri Releasing IL-22 (LR-IL-22) Facilitates Intestinal Radioprotection for Whole-Abdomen Irradiation (WAI) of Ovarian Cancer

Radiation research

Diala F Hamade

Alexis Espinal

Jian Yu

Brian J Leibowitz

Renee Fisher

...

2022/7/1

tRF3008A suppresses the progression and metastasis of colorectal cancer by destabilizing FOXK1 in an AGO-dependent manner

Journal of Experimental & Clinical Cancer Research

Ying Han

Yinghui Peng

Shanshan Liu

Xinwen Wang

Changjing Cai

...

2022/1/22

Engineered PD-1/TIGIT dual-activating cell-membrane nanoparticles with dexamethasone act synergistically to shape the effector T cell/Treg balance and alleviate systemic lupus …

Biomaterials

Qianqian Guo

Chuanrong Chen

Zhihua Wu

Wei Zhang

Liting Wang

...

2022/6/1

Intestinal Radiation Protection and Mitigation by Second-Generation Probiotic Lactobacillus-reuteri Engineered to Deliver Interleukin-22

International Journal of Molecular Sciences

Alexis Espinal

Michael W Epperly

Amitava Mukherjee

Renee Fisher

Donna Shields

...

2022/5/17

Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer

Proceedings of the National Academy of Sciences

Suisui Hao

Jingshan Tong

Anupma Jha

Denise Risnik

Darleny Lizardo

...

2022/12/20

Method of preventing or treating treatment-induced gastrointestinal injury

2022/4/28

Role of Receptor Interacting Protein (RIP) kinases in cancer

Kaylee Ermine

Jian Yu

Lin Zhang

2022/11/1

CDK4/6 inhibition suppresses p73 phosphorylation and activates DR5 to potentiate chemotherapy and immune checkpoint blockade

Cancer research

Jingshan Tong

Xiao Tan

Xiangping Song

Man Gao

Denise Risnik

...

2022/4/1

Dual inhibition of BET and HAT/p300 suppresses colorectal cancer via DR5-and p53/PUMA-mediated cell death

Frontiers in Oncology

Chaoyuan Kuang

Jingshan Tong

Kaylee Ermine

Manbo Cai

Fujun Dai

...

2022/10/12

Non-steroidal anti-inflammatory drugs induce immunogenic cell death in suppressing colorectal tumorigenesis

Oncogene

Rochelle Fletcher

Jingshan Tong

Denise Risnik

Brian J Leibowitz

Yi-Jun Wang

...

2021/3/18

BET protein degradation triggers DR5-mediated immunogenic cell death to suppress colorectal cancer and potentiate immune checkpoint blockade

Oncogene

Jingshan Tong

Xiao Tan

Denise Risnik

Man Gao

Xiangping Song

...

2021/12/2

Interferon β drives intestinal regeneration after radiation

Science Advances

Brian J Leibowitz

Guangyi Zhao

Liang Wei

Hang Ruan

Michael Epperly

...

2021/10/6

M6A “Writer” Gene METTL14: A Favorable Prognostic Biomarker and Correlated With Immune Infiltrates in Rectal Cancer

Frontiers in Oncology

Changjing Cai

Jie Long

Qiaoqiao Huang

Ying Han

Yinghui Peng

...

2021/6/17

Immunogenic cell death in colon cancer prevention and therapy

Hang Ruan

Brian J Leibowitz

Lin Zhang

Jian Yu

2020/7

See List of Professors in Jian Yu University(University of Pittsburgh)