Jia Xu
Icahn School of Medicine at Mount Sinai
H-index: 16
North America-United States
Top articles of Jia Xu
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation | JCI insight | Karen Mendelson Tiphaine C Martin Christie B Nguyen Min Hsu Jia Xu | 2024/3/22 |
A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma | Cancer Research | Royce Zhou Jia Xu Tiphaine Martin Alexis Zachem John He | 2023/4/4 |
Novel Allosteric Inhibitor-Derived AKT Proteolysis Targeting Chimeras (PROTACs) Enable Potent and Selective AKT Degradation in KRAS/BRAF Mutant Cells | Journal of medicinal chemistry | Xufen Yu Jia Xu Kaitlyn M Cahuzac Ling Xie Yudao Shen | 2022/10/5 |
Abstract LB195: AKT degradation selectively inhibits the growth of PI3K/PTEN pathway mutant cancers with wild type KRAS and BRAF by destabilizing Aurora kinase B | Cancer Research | Jia Xu Xufen Yu Tiphaine C Martin Ankita Bansal Kakit Cheung | 2022/6/15 |
Discovery of Potent, Selective, and In Vivo Efficacious AKT Kinase Protein Degraders via Structure–Activity Relationship Studies | Journal of medicinal chemistry | Xufen Yu Jia Xu Yudao Shen Kaitlyn M Cahuzac Kwang-su Park | 2022/2/4 |
AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway–Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B | Cancer discovery | Jia Xu Xufen Yu Tiphaine C Martin Ankita Bansal Kakit Cheung | 2021/12/1 |
Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders | Journal of medicinal chemistry | Xufen Yu Jia Xu Ling Xie Li Wang Yudao Shen | 2021/12/2 |
Mir-20a-5p induced WTX deficiency promotes gastric cancer progressions through regulating PI3K/AKT signaling pathway | Journal of Experimental & Clinical Cancer Research | Jian Li Danli Ye Peng Shen Xiaorong Liu Peirong Zhou | 2020/12 |
