Jens Luebeck

Jens Luebeck

University of California, San Diego

H-index: 17

North America-United States

About Jens Luebeck

Jens Luebeck, With an exceptional h-index of 17 and a recent h-index of 17 (since 2020), a distinguished researcher at University of California, San Diego, specializes in the field of ecDNA, bioinformatics, computational biology, gene amplification, cancer genomics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Oncogenic extrachromosomal DNA identification using whole-genome sequencing from formalin-fixed glioblastomas

CoRAL accurately resolves extrachromosomal DNA genome structures with long-read sequencing

Immortalization and transformation of primary cells mediated by engineered ecDNAs

Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change

Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma

Coordinated inheritance of extrachromosomal DNA species in human cancer cells

Epigenetic dysregulation from chromosomal transit in micronuclei

Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity

Jens Luebeck Information

University

Position

___

Citations(all)

1925

Citations(since 2020)

1821

Cited By

541

hIndex(all)

17

hIndex(since 2020)

17

i10Index(all)

18

i10Index(since 2020)

18

Email

University Profile Page

Google Scholar

Jens Luebeck Skills & Research Interests

ecDNA

bioinformatics

computational biology

gene amplification

cancer genomics

Top articles of Jens Luebeck

Oncogenic extrachromosomal DNA identification using whole-genome sequencing from formalin-fixed glioblastomas

Annals of Oncology

2024/3/15

CoRAL accurately resolves extrachromosomal DNA genome structures with long-read sequencing

bioRxiv

2024

Immortalization and transformation of primary cells mediated by engineered ecDNAs

bioRxiv

2023

Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change

bioRxiv

2023/12/13

Coordinated inheritance of extrachromosomal DNA species in human cancer cells

bioRxiv

2023/7/19

Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity

Proceedings of the National Academy of Sciences

2023/5/16

Transcriptional immune suppression and upregulation of double stranded DNA damage and repair repertoires in ecDNA-containing tumors

bioRxiv

2023/4/24

Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus

Nature

2023/4/27

METHODS AND COMPOSITIONS FOR DETECTING ecDNA

2022/11/17

FastViFi: Fast and accurate detection of (Hybrid) Viral DNA and RNA

NAR Genomics and Bioinformatics

2022/6

Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges

Cancer discovery

2021/1/1

Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA

Nature

2022/2/17

Extrachromosomal DNA in HPV-Mediated Oropharyngeal Cancer Drives Diverse Oncogene Transcription

Clinical Cancer Research

2021/12/15

FaNDOM: Fast nested distance-based seeding of optical maps

Patterns

2021/5/14

Reconstructing and Profiling Extrachromosomal DNA

2021

Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers

Nature genetics

2020/9

See List of Professors in Jens Luebeck University(University of California, San Diego)

Co-Authors

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