Jenifer Saffi

About Jenifer Saffi

Jenifer Saffi, With an exceptional h-index of 42 and a recent h-index of 24 (since 2020), a distinguished researcher at Universidade Federal de Ciências da Saúde de Porto Alegre, specializes in the field of DNA repair, Mutagenesis, Genetic Toxicology, Molecular Biology, Biochemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

Exploring the basis of heterogeneity of cancer aggressiveness among the mutated POLE variants

Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells

Laterality influence on gene expression of DNA damage repair in colorectal cancer

High Expression of MRE11A Is Associated with Shorter Survival and a Higher Risk of Death in CRC Patients

High Expression of MRE11A, the Gene Involved in the Resection Step During Homologous Recombination, Is Associated with Shorter Survival and a Higher Risk of Death in CRC Patients

Antioxidant and anticancer potential of the new Cu (II) complexes bearing imine-phenolate ligands with pendant amine N-donor groups

Synthesis, characterization, antioxidant potential, and cytotoxicity screening of new Cu (II) complexes with 4-(arylchalcogenyl)-1H-pyrazoles ligands

A novel 1-((3-(2-toluyl)-4, 5-dihydroisoxazol-5-yl) methyl)-4-(trifluoromethyl) pyrimidin-2 (1H)-one activates intrinsic mitochondria-dependent pathway and decreases …

Jenifer Saffi Information

University

Position

Biochemistry Professor/ Vice-Rector -

Citations(all)

5180

Citations(since 2020)

2200

Cited By

3811

hIndex(all)

42

hIndex(since 2020)

24

i10Index(all)

108

i10Index(since 2020)

71

Email

University Profile Page

Universidade Federal de Ciências da Saúde de Porto Alegre

Google Scholar

View Google Scholar Profile

Jenifer Saffi Skills & Research Interests

DNA repair

Mutagenesis

Genetic Toxicology

Molecular Biology

Biochemistry

Top articles of Jenifer Saffi

Title

Journal

Author(s)

Publication Date

Exploring the basis of heterogeneity of cancer aggressiveness among the mutated POLE variants

Janick Selves

Helena de Castro e Gloria

Anne-Cécile Brunac

Jenifer Saffi

Rosine Guimbaud

...

2024/1/1

Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells

Oncotarget

André Luiz Mendes Juchem

Cristiano Trindade

Juliana Bondan da Silva

Miriana da Silva Machado

Temenouga Nikolova Guecheva

...

2023

Laterality influence on gene expression of DNA damage repair in colorectal cancer

Scientific Reports

Juliano Oliveira-Silveira

Eduardo Filippi-Chiela

Jenifer Saffi

2023/9/25

High Expression of MRE11A Is Associated with Shorter Survival and a Higher Risk of Death in CRC Patients

Genes

Daniel de Barcellos Azambuja

Helena de Castro e Gloria

Gabriel e Silva Montenegro

Antonio Nocchi Kalil

Jean-Sébastien Hoffmann

...

2023/6/15

High Expression of MRE11A, the Gene Involved in the Resection Step During Homologous Recombination, Is Associated with Shorter Survival and a Higher Risk of Death in CRC Patients

Azambuja DdB

E Glória HdC

Montenegro GeS

AN Kalil

J Hoffmann

...

2023/5/16

Antioxidant and anticancer potential of the new Cu (II) complexes bearing imine-phenolate ligands with pendant amine N-donor groups

Pharmaceutics

Adriana Castro Pinheiro

Ianka Jacondino Nunes

Wesley Vieira Ferreira

Paula Pellenz Tomasini

Cristiano Trindade

...

2023/1/22

Synthesis, characterization, antioxidant potential, and cytotoxicity screening of new Cu (II) complexes with 4-(arylchalcogenyl)-1H-pyrazoles ligands

Journal of Inorganic Biochemistry

Adriana C Pinheiro

Franciele F Busatto

Bruna T Schaefer

Paula P Tomasini

Ianka J Nunes

...

2022/12/1

A novel 1-((3-(2-toluyl)-4, 5-dihydroisoxazol-5-yl) methyl)-4-(trifluoromethyl) pyrimidin-2 (1H)-one activates intrinsic mitochondria-dependent pathway and decreases …

European Journal of Pharmacology

Marcela Silva Dos Santos

Marcio Marçal Lobo

Simone Schneider Amaral

Nilo Zanatta

Cassiana Macagnan Viau

...

2021/5/15

Olaparib-mediated enhancement of 5-fluorouracil cytotoxicity in mismatch repair deficient colorectal cancer cells

BMC cancer

Helena de Castro e Gloria

Laura Jesuíno Nogueira

Patrícia Bencke Grudzinski

Paola Victória da Costa Ghignatti

Temenouga Nikolova Guecheva

...

2021/4/22

Functions of the CSB Protein at Topoisomerase 2 Inhibitors-Induced DNA Lesions

Frontiers in Cell and Developmental Biology

Franciele Faccio Busatto

Sofiane Y Mersaoui

Yilun Sun

Yves Pommier

Jean-Yves Masson

...

2021/10/22

Cell growth analysis and nucleotide excision repair modulation in breast cancer cells submitted to a protocol using doxorubicin and paclitaxel

Life Sciences

Franciele Faccio Busatto

Victoria Pereira Viero

Bruna Thaís Schaefer

Jenifer Saffi

2021/3/1

Efeito Cardioprotetor da Suplementação Materna com Resveratrol sobre a Toxicidade Induzida por Doxorrubicina em Cardiomiócitos de Neonatos

Arquivos Brasileiros de Cardiologia

Verônica Bidinotto Brito

Leopoldo Vinicius Martins Nascimento

Dinara Jaqueline Moura

Jenifer Saffi

2021/10/8

Promising breeding material of winter triticale in the conditions of the Middle Urals

BIO Web of Conferences

GN Potapova

NN Zezin

NL Zobnina

MS Ivanova

2021

Cardioprotective effect of maternal supplementation with resveratrol on toxicity induced by doxorubicin in offspring cardiomyocytes

Arquivos Brasileiros de Cardiologia

Verônica Bidinotto Brito

Leopoldo Vinicius Martins Nascimento

Dinara Jaqueline Moura

Jenifer Saffi

2021/10/8

Marcela Silva dos Santos, Marcio Marçal Lobo b, Simone Schneider Amaral c, Nilo Zanatta b

European Journal of Pharmacology

Cassiana Macagnan Viau

Jenifer Saffi

2021

Analyzing the opportunities to target DNA double-strand breaks repair and replicative stress responses to improve therapeutic index of colorectal cancer

Paula Pellenz Tomasini

Temenouga Nikolova Guecheva

Natalia Motta Leguisamo

Sarah Pericart

Anne-Cecile Brunac

...

2021/6/23

Synthesis, molecular structure and antioxidant activity of bis [L (μ2-chloro) copper (II)] supported by phenoxy/naphthoxy–imine ligands

Journal of inorganic biochemistry

Tamara Machado Dos Santos

Carolina Cristovao Martins

Danielle Tapia Bueno

Ianka Jacondino Nunes

Franciele Faccio Busatto

...

2020/9/1

The role of double‐strand break repair, translesion synthesis, and interstrand crosslinks in colorectal cancer progression—clinicopathological data and survival

Journal of Surgical Oncology

Gustavo A Laporte

Natalia M Leguisamo

Helena de Castro e Gloria

Daniel B Azambuja

Antonio N Kalil

...

2020/4

Cytotoxic mechanism of Bothrops jararaca venom mediated by mitochondrial depolarization

Adv Toxicol Toxic Effects

AM Morás

L Steffens

BE Nordio

J Saffi

DJ Moura

2020

See List of Professors in Jenifer Saffi University(Universidade Federal de Ciências da Saúde de Porto Alegre)

Co-Authors

H-index: 74
Jose Claudio Fonseca Moreira

Jose Claudio Fonseca Moreira

Universidade Federal do Rio Grande do Sul

H-index: 63
Leticia Costa-Lotufo

Leticia Costa-Lotufo

Universidade de São Paulo

H-index: 58
Carlos F M Menck

Carlos F M Menck

Universidade de São Paulo

H-index: 46
Arthur Fett-Neto

Arthur Fett-Neto

Universidade Federal do Rio Grande do Sul

H-index: 33
Diego Bonatto

Diego Bonatto

Universidade Federal do Rio Grande do Sul

H-index: 32
Dinara Jaqueline Moura

Dinara Jaqueline Moura

Universidade Federal de Ciências da Saúde de Porto Alegre

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