Jeffrey Holt
Harvard University
H-index: 48
North America-United States
Top articles of Jeffrey Holt
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
The natural history and genotype–phenotype correlations of TMPRSS3 hearing loss: an international, multi-center, cohort analysis | Human Genetics | Brett M Colbert Cris Lanting Molly Smeal Susan Blanton Derek M Dykxhoorn | 2024/4/30 |
TMC function, dysfunction, and restoration in mouse vestibular organs | Frontiers in Neurology | Evan M Ratzan John Lee Margot A Madison Hong Zhu Wu Zhou | 2024/4/4 |
TMEM63 proteins form monomeric high-threshold mechanosensitive ion channels | Biophysical Journal | Wang Zheng Shaun Rawson Swetha Murthy Maximilian H Ulbrich Marcos Sotomayor | 2024/2/8 |
Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels | eLife | Arnaud PJ Giese Wei-Hsiang Weng Katie S Kindt Hui Ho Vanessa Chang Jonathan S Montgomery | 2023/5/30 |
Materials and methods for delivering nucleic acids to cochlear and vestibular cells | 2022/1/20 | ||
Large gene vectors and delivery and uses thereof | 2023/3/23 | ||
TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels | Neuron | Wang Zheng Shaun Rawson Zhangfei Shen Elakkiya Tamilselvan Harper E Smith | 2023/10/18 |
Hearing preservation and spatial hearing outcomes after cochlear implantation in children with TMPRSS3 mutations | Otology & Neurotology | Z Ellen Peng Alejandro Garcia Shelly P Godar Jeffrey R Holt Daniel J Lee | 2023/1/1 |
Response to Letter to the Editor Regarding “Hearing Preservation and Spatial Hearing Outcomes after Cochlear Implantation in Children with TMPRSS3 Mutations” | Otology & Neurotology | Z Ellen Peng Alejandro Garcia Shelly P Godar Jeffrey R Holt Daniel J Lee | 2023/8/1 |
Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice | Science translational medicine | Barbara K Mathiesen Leo M Miyakoshi Christopher R Cederroth Evangelia Tserga Corstiaen Versteegh | 2023/6/28 |
Genotype-Phenotype Correlations in TMPRSS3 (DFNB10/DFNB8) with Emphasis on Natural History | Eric Nisenbaum Denise Yan A Eliot Shearer Evan de Joya Torin Thielhelm | 2023/12/5 | |
Molecular earplugs to protect the inner ear | Molecular Therapy-Methods & Clinical Development | Mary G Chaves Jeffrey R Holt | 2023/6/8 |
Efficient viral transduction in fetal and adult human inner ear explants with AAV9-PHP. B vectors | Biomolecules | Edward SA van Beelen Wouter H van der Valk Thijs O Verhagen John CMJ de Groot Margot A Madison | 2022/6/10 |
Methods and compositions for allele specific gene editing | 2022/4/14 | ||
pH regulates potassium conductance and drives a constitutive proton current in human TMEM175 | Science Advances | Wang Zheng Chen Shen Longfei Wang Shaun Rawson Wen Jun Xie | 2022/3/25 |
Compositions and methods for gene replacement | 2022/12/15 | ||
Optimized AAV vectors for TMC1 gene therapy in a humanized mouse model of DFNB7/11 | Biomolecules | Irina Marcovich Nicholas K Baer Olga Shubina-Oleinik Rachel Eclov Clayton W Beard | 2022/6/29 |
Sensory transduction is required for normal development and maturation of cochlear inner hair cell synapses | Elife | John Lee Kosuke Kawai Jeffrey R Holt Gwenaëlle SG Géléoc | 2021/11/4 |
The mechanosensory transduction machinery in inner ear hair cells | Wang Zheng Jeffrey R Holt | 2021/5/6 | |
Single and dual vector gene therapy with AAV9-PHP. B rescues hearing in Tmc1 mutant mice | Molecular Therapy | Jason Wu Paola Solanes Carl Nist-Lund Sofia Spataro Olga Shubina-Oleinik | 2021/3/3 |
