Jeffrey D. Rothstein
Johns Hopkins University
H-index: 131
North America-United States
Top articles of Jeffrey D. Rothstein
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
Counter-regulation of RNA stability by UPF1 and TDP43 | bioRxiv | Nicolas Gomez Caroline Hsieh Xingli Li Megan Dykstra Jacob Waksmacki | 2024/2/4 |
G2C4 targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in human C9orf72 ALS/FTD induced pluripotent stem cell derived neurons | Acta neuropathologica | Jeffrey D Rothstein Victoria Baskerville Sampath Rapuri Emma Mehlhop Paymaan Jafar-Nejad | 2024/6 |
Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controls | Nature Communications | Stanislav Tsitkov Kelsey Valentine Velina Kozareva Aneesh Donde Aaron Frank | 2024/5/2 |
Apilimod dimesylate in C9orf72 amyotrophic lateral sclerosis: a randomized phase 2a clinical trial | Brain | Suma Babu Katharine A Nicholson Jeffrey D Rothstein Andrea Swenson Paul J Sampognaro | 2024/4/12 |
Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis | Elife | Kyounghee Min Batuhan Yenilmez Mark Kelly Dimas Echeverria Michael Elleby | 2024/4/2 |
Monocarboxylate transporters facilitate succinate uptake into brown adipocytes | Nature Metabolism | Anita Reddy Sally Winther Nhien Tran Haopeng Xiao Josefine Jakob | 2024/2/20 |
Nuclear pore dysfunction and disease: a complex opportunity | Charlotte M Fare Jeffrey D Rothstein | 2024/12/31 | |
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency | Scientific Data | Andrea D Matlock Vineet Vaibhav Ronald Holewinski Vidya Venkatraman Victoria Dardov | 2023/1/11 |
Methods for inhibiting chmp7 expression in neuronal cells for the treatment of neurodegenerative disorders | 2023/12/21 | ||
Highly variable molecular signatures of TDP-43 loss of function are associated with nuclear pore complex injury in a population study of sporadic ALS patient iPSNs | bioRxiv | Jeffrey D Rothstein Caroline Warlick Alyssa N Coyne | 2023 |
Phase 3B extension study evaluating superiority of daily vs approved on/off oral edaravone dosing in patients with amyotrophic lateral sclerosis | Journal of the Neurological Sciences | Jeffrey Rothstein Shari Desilva Lorne Zinman Marvin Chum Adriano Chio | 2023/12/1 |
Disease related changes in ATAC-Seq of more than 450 iPSC-derived motor neuron lines from ALS patients and controls | bioRxiv | Stanislav Tsitkov Kelsey Valentine Velina Kozareva Aneesh Donde Aaron Frank | 2023 |
Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias | Cell genomics | Karri Kaivola Ruth Chia Jinhui Ding Memoona Rasheed Masashi Fujita | 2023/6/14 |
Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects | Neuron | Michael J Workman Ryan G Lim Jie Wu Aaron Frank Loren Ornelas | 2023/4/19 |
Methods of treating or preventing conditions of dendritic and neural spine defects | 2022/2/10 | ||
Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins | Science translational medicine | Junli Gao Quinlan T Mewborne Amandeep Girdhar Udit Sheth Alyssa N Coyne | 2022/9/14 |
Nuclear pore dysfunction in neurodegeneration | Olivia Spead Benjamin L Zaepfel Jeffrey D Rothstein | 2022/7 | |
Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines | Nature neuroscience | Emily G Baxi Terri Thompson Jonathan Li Julia A Kaye Ryan G Lim | 2022/2 |
Nerve Regeneration Following Ablation Of Monocarboxylate Transporters 1, 2 And 4 From Schwann Cells | Journal Of The Peripheral Nervous System | Joseph Passero Atul Rawat Fang Yang Filipa Boucanova Luca Bartesaghi | 2022/7/1 |
Prevention of Nuclear Pore Injury in Sporadic and C9orf72 ALS/FTD: Antisense Inhibition of CHMP7 | Jeffrey D Rothstein | 2022/8/1 |