Jeffrey Aube

About Jeffrey Aube

Jeffrey Aube, With an exceptional h-index of 67 and a recent h-index of 35 (since 2020), a distinguished researcher at University of North Carolina at Chapel Hill, specializes in the field of Chemistry, medicinal chemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase

MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth

The Hybrid Antibiotic Thiomarinol A Overcomes Intrinsic Resistance in Escherichia coli Using a Privileged Dithiolopyrrolone Moiety

Selective d3 dopamine receptor agonists and methods of their use

Functional inhibition of the RNA‐binding protein HuR sensitizes triple‐negative breast cancer to chemotherapy

SETD2 maintains nuclear lamina stability to safeguard the genome

Mixed, nonclassical behavior in a classic allosteric protein

Type I interferons drive MAIT cell functions against bacterial pneumonia

Jeffrey Aube Information

University

Position

___

Citations(all)

14025

Citations(since 2020)

5138

Cited By

10779

hIndex(all)

67

hIndex(since 2020)

35

i10Index(all)

240

i10Index(since 2020)

129

Email

University Profile Page

Google Scholar

Jeffrey Aube Skills & Research Interests

Chemistry

medicinal chemistry

Top articles of Jeffrey Aube

Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase

Science Advances

2024/3/15

MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth

bioRxiv

2024/1/20

The Hybrid Antibiotic Thiomarinol A Overcomes Intrinsic Resistance in Escherichia coli Using a Privileged Dithiolopyrrolone Moiety

ACS Infectious Diseases

2024/1/16

Selective d3 dopamine receptor agonists and methods of their use

2023/10/5

Functional inhibition of the RNA‐binding protein HuR sensitizes triple‐negative breast cancer to chemotherapy

Molecular Oncology

2023/10

SETD2 maintains nuclear lamina stability to safeguard the genome

bioRxiv

2023/9/28

Mixed, nonclassical behavior in a classic allosteric protein

Proceedings of the National Academy of Sciences

2023/9/19

Type I interferons drive MAIT cell functions against bacterial pneumonia

Journal of Experimental Medicine

2023/7/26

Targeting RNA-binding protein HuR to inhibit the progression of renal tubular fibrosis

Journal of Translational Medicine

2023/6/30

Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas

ACS Medicinal Chemistry Letters

2023/6/26

ASSOCIATION BETWEEN PROMYELOCYTIC LEUKEMIA ZINC FINGER (PLZF) METHYLATION AND EXPRESSION AND CIRCULATING MUCOSAL ASSOCIATED INVARIANT T (MAIT) CELL FUNCTION IN PATIENTS WITH SEPSIS

STATEMENT OF DISSERTATION APPROVAL

2023/5

Abstract P1-13-08: Inhibition of RNA binding protein HuR function sensitizes the TNBC to chemotherapy

Cancer Research

2023/3/1

Small molecules targeting the RNA-binding protein HuR inhibit tumor growth in xenografts

Journal of medicinal chemistry

2023/1/23

HuR inhibition reduces post-ischemic cardiac remodeling by dampening acute inflammatory gene expression and the innate immune response

bioRxiv

2023/1/18

New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science

2021/9/30

Enhancing Mucosal-Associated Invariant T Cell Function and Expansion with Human Selective Serum

ImmunoHorizons

2023/1/1

HuR-dependent expression of Wisp1 is necessary for TGFβ-induced cardiac myofibroblast activity

Journal of molecular and cellular cardiology

2023/1/1

In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas

Journal of Medicinal Chemistry

2022/1/19

Use of a MAIT-activating ligand, 5-OP-RU, as a mucosal adjuvant in a murine model of Vibrio cholerae O1 vaccination

Pathogens and Immunity

2022

Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology

Alzheimer's & Dementia: Translational Research & Clinical Interventions

2022

See List of Professors in Jeffrey Aube University(University of North Carolina at Chapel Hill)

Co-Authors

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