Jeffrey Aube

Jeffrey Aube

University of North Carolina at Chapel Hill

H-index: 67

North America-United States

About Jeffrey Aube

Jeffrey Aube, With an exceptional h-index of 67 and a recent h-index of 35 (since 2020), a distinguished researcher at University of North Carolina at Chapel Hill, specializes in the field of Chemistry, medicinal chemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth

The Hybrid Antibiotic Thiomarinol A Overcomes Intrinsic Resistance in Escherichia coli Using a Privileged Dithiolopyrrolone Moiety

Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase

HuR-dependent expression of Wisp1 is necessary for TGFβ-induced cardiac myofibroblast activity

Mixed, nonclassical behavior in a classic allosteric protein

Abstract P1-13-08: Inhibition of RNA binding protein HuR function sensitizes the TNBC to chemotherapy

Type I interferons drive MAIT cell functions against bacterial pneumonia

Small molecules targeting the RNA-binding protein HuR inhibit tumor growth in xenografts

Jeffrey Aube Information

University

Position

___

Citations(all)

14025

Citations(since 2020)

5138

Cited By

10779

hIndex(all)

67

hIndex(since 2020)

35

i10Index(all)

240

i10Index(since 2020)

129

Email

University Profile Page

University of North Carolina at Chapel Hill

Google Scholar

View Google Scholar Profile

Jeffrey Aube Skills & Research Interests

Chemistry

medicinal chemistry

Top articles of Jeffrey Aube

Title

Journal

Author(s)

Publication Date

MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth

bioRxiv

Olivia J Cheng

Eric J Lebish

Owen Jensen

Damian Jacenik

Shubhanshi Trivedi

...

2024/1/20

The Hybrid Antibiotic Thiomarinol A Overcomes Intrinsic Resistance in Escherichia coli Using a Privileged Dithiolopyrrolone Moiety

ACS Infectious Diseases

Rachel M Johnson

Kelin Li

Xiaoyan Chen

Gina L Morgan

Jeffrey Aubé

...

2024/1/16

Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase

Science Advances

Amrita Singh

Samantha Ottavi

Inna Krieger

Kyle Planck

Andrew Perkowski

...

2024/3/15

HuR-dependent expression of Wisp1 is necessary for TGFβ-induced cardiac myofibroblast activity

Journal of molecular and cellular cardiology

Lisa C Green

Samuel Slone

Sarah R Anthony

Adrienne R Guarnieri

Sharon Parkins

...

2023/1/1

Mixed, nonclassical behavior in a classic allosteric protein

Proceedings of the National Academy of Sciences

Paul J Sapienza

Jeffrey P Bonin

HP Dinusha Jinasena

Kelin Li

Henry Dieckhaus

...

2023/9/19

Abstract P1-13-08: Inhibition of RNA binding protein HuR function sensitizes the TNBC to chemotherapy

Cancer Research

Lanjing Wei

Qi Zhang

Cuncong Zhong

Jeffrey Aubé

Danny R Welch

...

2023/3/1

Type I interferons drive MAIT cell functions against bacterial pneumonia

Journal of Experimental Medicine

Juan Carlos López-Rodríguez

Steven J Hancock

Kelin Li

Stefania Crotta

Christopher Barrington

...

2023/7/26

Small molecules targeting the RNA-binding protein HuR inhibit tumor growth in xenografts

Journal of medicinal chemistry

Xiaoqing Wu

Remya Ramesh

Jinan Wang

Youguang Zheng

Ahlam M Armaly

...

2023/1/23

HuR inhibition reduces post-ischemic cardiac remodeling by dampening acute inflammatory gene expression and the innate immune response

bioRxiv

Samuel Slone

Sarah R Anthony

Lisa C Green

Michelle L Nieman

Perwez Alam

...

2023/1/18

Targeting RNA-binding protein HuR to inhibit the progression of renal tubular fibrosis

Journal of Translational Medicine

Zhimin Huang

Simeng Liu

Anna Tang

Xiaoqing Wu

Jeffrey Aube

...

2023/6/30

Selective d3 dopamine receptor agonists and methods of their use

2023/10/5

New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science

Christa E Müller

Finn K Hansen

Michael Gütschow

Craig W Lindsley

Dennis Liotta

2021/9/30

Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas

ACS Medicinal Chemistry Letters

Samantha Ottavi

Kelin Li

Jackson G Cacioppo

Andrew J Perkowski

Remya Ramesh

...

2023/6/26

Functional inhibition of the RNA‐binding protein HuR sensitizes triple‐negative breast cancer to chemotherapy

Molecular Oncology

Lanjing Wei

Qi Zhang

Cuncong Zhong

Lily He

Yuxia Zhang

...

2023/10

Enhancing Mucosal-Associated Invariant T Cell Function and Expansion with Human Selective Serum

ImmunoHorizons

Daniel Labuz

Jackson Cacioppo

Kelin Li

Jeffrey Aubé

Daniel T Leung

2023/1/1

ASSOCIATION BETWEEN PROMYELOCYTIC LEUKEMIA ZINC FINGER (PLZF) METHYLATION AND EXPRESSION AND CIRCULATING MUCOSAL ASSOCIATED INVARIANT T (MAIT) CELL FUNCTION IN PATIENTS WITH SEPSIS

STATEMENT OF DISSERTATION APPROVAL

D Labuz

O Cheng

R Campbell

T Blair

J Cacioppo

...

2023/5

SETD2 maintains nuclear lamina stability to safeguard the genome

bioRxiv

Abid Khan

James M Metts

Lucas C Collins

C Allie Mills

Kelin Li

...

2023/9/28

Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions

ACS infectious diseases

Ben Gold

Jun Zhang

Landys Lopez Quezada

Julia Roberts

Yan Ling

...

2022/2/22

Discovery and optimization of pyrrolopyrimidine derivatives as selective disruptors of the perinucleolar compartment, a marker of tumor progression toward metastasis

Journal of medicinal chemistry

Kevin J Frankowski

Samarjit Patnaik

Chen Wang

Noel Southall

Dipannita Dutta

...

2022/6/13

AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

Alzheimer's & Dementia: Translational Research & Clinical Interventions

Frances M Potjewyd

Joel K Annor‐Gyamfi

Jeffrey Aubé

Shaoyou Chu

Ivie L Conlon

...

2022

See List of Professors in Jeffrey Aube University(University of North Carolina at Chapel Hill)

Co-Authors

H-index: 143
BL Roth

BL Roth

University of North Carolina at Chapel Hill

H-index: 58
Dean Tantillo

Dean Tantillo

University of California, Davis

H-index: 52
Liang Xu, M.D., Ph.D.

Liang Xu, M.D., Ph.D.

University of Kansas

H-index: 51
Tom Prisinzano

Tom Prisinzano

University of Kentucky

H-index: 48
Fusao Takusagawa

Fusao Takusagawa

University of Kansas

H-index: 48
Dan A. Dixon

Dan A. Dixon

University of Kansas

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